Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Ph-chromosome"'
Autor:
Alessandro Laganà, Matteo Totaro, Maria Laura Bisegna, Loredana Elia, Stefania Intoppa, marco Beldinanzi, Mabel Matarazzo, Mariangela di Trani, Alessandro Costa, Raffaele Maglione, Biancamaria Mandelli, Sabina Chiaretti, Maurizio Martelli, Maria Stefania De Propris
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
Background: B-lineage acute lymphoblastic leukemias (B-ALL) harboring the t(9;22)(q34;q11)/BCR::ABL1rearrangement, represent a category with previously dismal prognosis whose management and outcome dramatically changed thanks to the use of tyrosine k
Externí odkaz:
https://doaj.org/article/e29c4b9f93a64e38ba922c03229d13d1
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTMyelodysplastic syndromes (MDS) refer to a set of clonal hematopoietic disorders with fusion transcript as disease progression. Breakpoint cluster region/abelson (BCR::ABL) fusion mostly occurs during the progressive phase from MDS to higher
Externí odkaz:
https://doaj.org/article/380c001401df4db782bb01a6cea55458
Akademický článek
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Autor:
Yuan Kong, Yi-Lin Wu, Yang Song, Min-Min Shi, Xie-Na Cao, Hong-Yan Zhao, Ya-Zhen Qin, Yue-Yun Lai, Hao Jiang, Qian Jiang, Xiao-Jun Huang
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-13 (2017)
Abstract Background As one of the major treatment obstacles in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL), relapse of Ph+ALL may result from the persistence of leukemia-propagating cells (LPCs). Research using a xenograft
Externí odkaz:
https://doaj.org/article/9d5a67f8c60c473ba3b131eb3c03b5d5
Autor:
Daigo Hashimoto, Nanase Okazaki, Masahiro Onozawa, Junichi Sugita, Daisuke Hidaka, Shinichi Fujisawa, Atsushi Yasumoto, Keito Suto, Naoki Miyashita, Hiroyuki Ohigashi, Yoshihiro Matsuno, Takanori Teshima
Publikováno v:
Internal Medicine. 61:1049-1054
Right neck swelling and pain occurred in a 49-year-old man. A Blood count showed a slight increase in platelet count without leukemoid reaction. After a biopsy of the cervical mass and bone marrow aspiration, a diagnosis of extramedullary blast crisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e30a163cf7166e7c7fbf95550126a9
https://doi.org/10.2169/internalmedicine.8319-21
https://doi.org/10.2169/internalmedicine.8319-21
CML is caused by a genetic change (mutation) in the stem cells produced by the bone marrow.The mutation causes the stem cells to produce too many underdeveloped white blood cells. It also leads to a reduction in the number of other blood cells, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2138d3f767b4758927893fd571367d62
Akademický článek
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Akademický článek
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Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 55, Iss 2, Pp 196-201 (2012)
Background: The conventional cytogenetic approach to demonstrate Philadelphia (Ph) chromosome at times does not yield enough number of metaphases or are of suboptimal quality. Further, the rapid molecular tests have completely pushed this simple tech
Externí odkaz:
https://doaj.org/article/1051e288f2df48388f34056e8ab812b7
Autor:
Dilhan Kuru, Yelda Tarkan Argüden, Muhlis Cem Ar, Ayşe Çırakoğlu, Şeniz Öngören, Şükriye Yılmaz, Ahmet Emre Eşkazan, Ayhan Deviren, Teoman Soysal, Seniha Hacıhanefioğlu, Birsen Ülkü
Publikováno v:
Turkish Journal of Hematology, Vol 28, Iss 03, Pp 186-192 (2011)
Objective: The Philadelphia (Ph) chromosome, consisting of the t(9;22)(q34;q11) translocation, is observed in ~90% of patients with chronic myeloid leukemia (CML). Variant Ph translocations are observed in 5%-10% of CML patients. In variant transloca
Externí odkaz:
https://doaj.org/article/2ecd7491b74f46fe8ad1a70931bb2d19