Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Ph, Howarth"'
Publikováno v:
‘Finding Neverland’ – T2 inflammation and its absence.
Autor:
S Montefort, WR Roche, PH Howarth, R Djukanovic, C Gratziou, M Carroll, L Smith, KM Britten, D Haskard, TH Lee, al. et
Publikováno v:
European Respiratory Journal. 5:815-823
Bronchial lavage and biopsy studies suggest the involvement of eosinophils and T-lymphocytes in allergic inflammation in asthma. There is evidence suggesting that the expression of adhesion molecules on endothelial cells and of their receptors on leu
Publikováno v:
Europe PubMed Central
Allergic mucosal inflammation is characterized by the presence of cell infiltration, predominantly with IgE-sensitized mast cells and activated eosinophils, and appears to be regulated by the local production and release of several cytokines, particu
Autor:
Ratko Djukanovic, Ck, Lai, Jw, Wilson, Km, Britten, Sj, Wilson, Wr, Roche, Ph, Howarth, St, Holgate
Publikováno v:
Europe PubMed Central
We studied the role of atopy, as defined by positive skin tests to common inhalant allergens, in allergic bronchial inflammation. Endobronchial biopsies were taken via the fibreoptic bronchoscope in 13 symptomatic atopic asthmatics, 10 atopic nonasth
Autor:
Montefort S, Wr, Roche, Ph, Howarth, Ratko Djukanovic, Gratziou C, Carroll M, Smith L, Km, Britten, Haskard D, Th, Lee
Publikováno v:
Europe PubMed Central
Bronchial lavage and biopsy studies suggest the involvement of eosinophils and T-lymphocytes in allergic inflammation in asthma. There is evidence suggesting that the expression of adhesion molecules on endothelial cells and of their receptors on leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::45f887d855bd930cf691d59634e646c5
http://europepmc.org/abstract/med/1379941
http://europepmc.org/abstract/med/1379941
Autor:
Jabeen MF; Nuffield Department of Medicine, Experimental Medicine Division, Respiratory Medicine Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK., Sanderson ND; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK., Tinè M; Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy., Donachie G; Nuffield Department of Medicine, Experimental Medicine Division, Respiratory Medicine Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK., Barber C; Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories and NIHR Southampton Respiratory Biomedical Research Unit, Southampton University, Southampton, UK., Azim A; Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories and NIHR Southampton Respiratory Biomedical Research Unit, Southampton University, Southampton, UK., Lau LCK; Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories and NIHR Southampton Respiratory Biomedical Research Unit, Southampton University, Southampton, UK., Brown T; Portsmouth Hospitals NHS Trust, Portsmouth, UK., Pavord ID; Nuffield Department of Medicine, Experimental Medicine Division, Respiratory Medicine Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK., Chauhan A; Portsmouth Hospitals NHS Trust, Portsmouth, UK., Klenerman P; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.; Nuffield Department of Clinical Medicine, Peter Medawar Building for Pathogen Research and Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Street TL; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK., Marchi E; Nuffield Department of Medicine, Experimental Medicine Division, Respiratory Medicine Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.; Nuffield Department of Clinical Medicine, Peter Medawar Building for Pathogen Research and Translational Gastroenterology Unit, University of Oxford, Oxford, UK., Howarth PH; Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Sir Henry Wellcome Laboratories and NIHR Southampton Respiratory Biomedical Research Unit, Southampton University, Southampton, UK., Hinks TSC; Nuffield Department of Medicine, Experimental Medicine Division, Respiratory Medicine Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Nuffield Department of Clinical Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.
Publikováno v:
Allergy [Allergy] 2024 Nov; Vol. 79 (11), pp. 2966-2980. Date of Electronic Publication: 2024 Aug 11.
Autor:
Buchheit KM; Division of Allergy and Clinical Immunology, AERD Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Shaw D; Department of Respiratory Medicine and Thoracic Surgery, Institute for Lung Health, Glenfield Hospital, Leicester, UK., Chupp G; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA., Lehtimaki L; Faculty of Medicine and Health Technology, Allergy Centre, Tampere University Hospital, Tampere University, Tampere, Finland., Heffler E; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Personalized Medicine, Asthma and Allergy Clinic, IRCCS Humanitas Research Hospital, Milan, Italy., Finney-Hayward T; Global Medical Affairs, Respiratory Specialty Care, GSK, London, UK., Zangrilli J; Clinical Science, GSK, Collegeville, Pennsylvania, USA., Kwiatek J; US Medical Affairs, GSK, Collegeville, Pennsylvania, USA., Siddiqui S; National Heart and Lung Institute, NIHR Imperial Biomedical Research Centre, Imperial College London, London, UK., Roufosse F; Department of Internal Medicine, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium., Thamboo A; Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada., West N; School of Pharmacy and Medical Sciences, Griffith University, Southport, Queensland, Australia., Vichiendilokkul A; Clinical Science, GSK, Collegeville, Pennsylvania, USA., Hellings PW; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.; Upper Airways Disease Research Unit, University of Ghent, Ghent, Belgium., Peters A; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Howarth PH; Global Medical Affairs, Respiratory Specialty Care, GSK, London, UK.
Publikováno v:
Allergy [Allergy] 2024 Oct; Vol. 79 (10), pp. 2662-2679.
Autor:
Rupani H; Department of Respiratory Medicine, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, Hampshire, UK., Busse WW; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA., Howarth PH; Global Medical, Global Specialty and Primary Care, GSK, Brentford, Middlesex, UK., Bardin PG; Monash Lung Sleep Allergy and Immunology, Monash University and Medical Centre and Hudson Institute, Melbourne, Victoria, Australia., Adcock IM; Airway Disease Section, National Heart and Lung Institute, Imperial College London, London, UK., Konno S; Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Jackson DJ; Guy's Severe Asthma Centre, Guy's and St Thomas' Hospitals, London, UK.; School of Immunology and Microbial Sciences, King's College London, London, UK.
Publikováno v:
Allergy [Allergy] 2024 Oct; Vol. 79 (10), pp. 2589-2604. Date of Electronic Publication: 2024 Aug 01.
Autor:
Djukanović R; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton and National Institute for Health and Care Research Southampton Biomedical Research Centre, Southampton, United Kingdom., Brinkman P; Department of Respiratory Medicine, Amsterdam University Medical Center, University of Amsterdam, the Netherlands., Kolmert J; Institute of Environmental Medicine, Karolinska Institutet, and the Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Gomez C; Institute of Environmental Medicine, Karolinska Institutet, and the Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Schofield J; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton and National Institute for Health and Care Research Southampton Biomedical Research Centre, Southampton, United Kingdom.; Biological Sciences, University of Southampton, Southampton, United Kingdom., Brandsma J; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton and National Institute for Health and Care Research Southampton Biomedical Research Centre, Southampton, United Kingdom., Shapanis A; Biological Sciences, University of Southampton, Southampton, United Kingdom., Skipp PJS; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton and National Institute for Health and Care Research Southampton Biomedical Research Centre, Southampton, United Kingdom.; Biological Sciences, University of Southampton, Southampton, United Kingdom., Postle A; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton and National Institute for Health and Care Research Southampton Biomedical Research Centre, Southampton, United Kingdom., Wheelock C; Institute of Environmental Medicine, Karolinska Institutet, and the Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Dahlen SE; Institute of Environmental Medicine, Karolinska Institutet, and the Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Sterk PJ; Department of Respiratory Medicine, Amsterdam University Medical Center, University of Amsterdam, the Netherlands., Brown T; Portsmouth Hospitals University National Health Service Trust, Queen Alexandra Hospital, Portsmouth, United Kingdom., Jackson DJ; Guy's Severe Asthma Centre, School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Mansur A; University of Birmingham and Heartlands Hospital, University Hospitals Birmingham National Health Service Foundation Trust, Birmingham, United Kingdom., Pavord I; Oxford Respiratory National Institute for Health and Care Research Biomedical Research Centre, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Patel M; Respiratory Medicine and R&D, University Hospitals Plymouth National Health Service Trust, Plymouth, United Kingdom., Brightling C; Institute for Lung Health and Leicester National Institute for Health and Care Research Biomedical Research Centre, University of Leicester, Leicester, United Kingdom., Siddiqui S; Institute for Lung Health and Leicester National Institute for Health and Care Research Biomedical Research Centre, University of Leicester, Leicester, United Kingdom., Bradding P; Institute for Lung Health and Leicester National Institute for Health and Care Research Biomedical Research Centre, University of Leicester, Leicester, United Kingdom., Sabroe I; Clinical Research Facility, Sheffield Teaching Hospitals National Health Service Foundation Trust, Sheffield, United Kingdom., Saralaya D; Bradford Institute for Health Research and the National Patient Recruitment Centre, Bradford, United Kingdom., Chishimba L; Clinical Sciences, Liverpool University Hospitals National Health Service Foundation Trust, Liverpool, United Kingdom., Porter J; University College London Respiratory and National Institute for Health and Care Research University College London Hospitals Biomedical Research Centre, London, United Kingdom., Robinson D; University College London Respiratory and National Institute for Health and Care Research University College London Hospitals Biomedical Research Centre, London, United Kingdom., Fowler S; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom.; Manchester Academic Health Science Centre and National Institute for Health and Care Research Manchester Biomedical Research Centre, Manchester University Hospitals National Health Service Foundation Trust, Manchester, United Kingdom., Howarth PH; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton and National Institute for Health and Care Research Southampton Biomedical Research Centre, Southampton, United Kingdom., Little L; Southampton Clinical Trials Unit, University of Southampton, and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom., Oliver T; Southampton Clinical Trials Unit, University of Southampton, and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom., Hill K; Southampton Clinical Trials Unit, University of Southampton, and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom., Stanton L; Southampton Clinical Trials Unit, University of Southampton, and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom., Allen A; Southampton Clinical Trials Unit, University of Southampton, and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom., Ellis D; Southampton Clinical Trials Unit, University of Southampton, and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom., Griffiths G; Southampton Clinical Trials Unit, University of Southampton, and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom., Harrison T; Nottingham Respiratory National Institute for Health and Care Research Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom., Akenroye A; Division of Allergy and Clinical Immunology and.; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Lasky-Su J; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Heaney L; Wellcome-Wolfson Institute for Experimental Medicine, Belfast, Northern Ireland; and., Chaudhuri R; Gartnavel General Hospital and School of Infection & Immunity, University of Glasgow, Glasgow, United Kingdom., Kurukulaaratchy R; School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton and National Institute for Health and Care Research Southampton Biomedical Research Centre, Southampton, United Kingdom.
Publikováno v:
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2024 Aug 01; Vol. 210 (3), pp. 288-297.
Autor:
Yasinska V; Clinical Lung and Allergy Research, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Gómez C; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Kolmert J; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Ericsson M; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.; Clinical Pharmacology, Karolinska University Hospital, Stockholm, Sweden.; Laboratoire AntiDopage Français, Université Paris-Saclay, Châtenay-Malabry, France., Pohanka A; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.; Clinical Pharmacology, Karolinska University Hospital, Stockholm, Sweden., James A; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Andersson LI; Clinical Lung and Allergy Research, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Sparreman-Mikus M; Clinical Lung and Allergy Research, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Sousa AR; Respiratory and Speciality Group, GSK, Clinical Sciences, Stockley Park, UK., Riley JH; Respiratory and Speciality Group, GSK, Clinical Sciences, Stockley Park, UK., Bates S; Respiratory and Speciality Group, GSK, Clinical Sciences, Stockley Park, UK., Bakke PS; Institute of Clinical Science, University of Bergen, Bergen, Norway., Zounemat Kermani N; National Heart and Lung Institute and Data Science Institute, Imperial College London, London, UK., Caruso M; Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy., Chanez P; Assistance Publique des Hôpitaux de Marseille, Clinique des Bronches, Allergies et Sommeil, Aix Marseille Université, Marseille, France., Fowler SJ; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK.; Manchester Academic Health Science Centre and NIHR Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Geiser T; Department of Pulmonary Medicine, University Hospital, University of Bern, Bern, Switzerland., Howarth PH; Faculty of Medicine, Southampton University, Southampton, UK.; NIHR Southampton Respiratory Biomedical Research Center, University Hospital Southampton, Southampton, UK., Horváth I; Department of Public Health, Semmelweis University, Budapest, Hungary.; National Koranyi Institute for Pulmonology, Budapest, Hungary., Krug N; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany., Montuschi P; National Heart and Lung Institute and Data Science Institute, Imperial College London, London, UK.; Department of Pharmacology, Faculty of Medicine, Catholic University of the Sacred Heart, Rome, Italy., Sanak M; Department of Internal Medicine, Jagiellonian University Medical College, Krakow, Poland., Behndig A; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Shaw DE; Nottingham NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK., Knowles RG; Knowles Consulting, Stevenage Bioscience Catalyst, Stevenage, UK., Dahlén B; Clinical Lung and Allergy Research, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Maitland-van der Zee AH; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Sterk PJ; Department of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Djukanovic R; Faculty of Medicine, Southampton University, Southampton, UK.; NIHR Southampton Respiratory Biomedical Research Center, University Hospital Southampton, Southampton, UK., Adcock IM; National Heart and Lung Institute and Data Science Institute, Imperial College London, London, UK., Chung KF; National Heart and Lung Institute and Data Science Institute, Imperial College London, London, UK., Wheelock CE; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Dahlén SE; Clinical Lung and Allergy Research, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.; Department of Respiratory Medicine, Karolinska University Hospital, Stockholm, Sweden.; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Wikström Jonsson E; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.; Clinical Pharmacology, Karolinska University Hospital, Stockholm, Sweden.
Publikováno v:
ERJ open research [ERJ Open Res] 2023 Oct 02; Vol. 9 (5). Date of Electronic Publication: 2023 Oct 02 (Print Publication: 2023).