Zobrazeno 1 - 10
of 510
pro vyhledávání: '"Pg, Pelicci"'
Publikováno v:
ecancermedicalscience
The Melanoma Independent Board (MIB) held its first conference from 21 to 22 October, 2013, in Rome, Italy. Like the MIB itself, the conference brought together specialists from all aspects of cancer care: doctors, patient associations, journalists,
Autor:
Ff, Ferrara, Fazi F, Bianchini A, Padula F, Gelmetti V, Minucci S, Mancini M, Pg, Pelicci, Lo Coco F, Clara NERVI
Publikováno v:
Scopus-Elsevier
Publons
Europe PubMed Central
Publons
Europe PubMed Central
Histone deacetylase (HDAC)-dependent transcriptional repression of the retinoic acid (RA)-signaling pathway underlies the differentiation block of acute promyelocytic leukemia. RA treatment relieves transcriptional repression and triggers differentia
Autor:
Bonati A, Carmelo Carlo-Stella, Lunghi P, Albertini R, Pinelli S, Migliaccio E, Sammarelli G, Savoldo B, Tabilio A, Pp, Dall Aglio, Pg, Pelicci
Publikováno v:
Europe PubMed Central
The BCR/ABL fusion protein is a constitutively active tyrosine kinase that is responsible for the pathogenesis of chronic myelogenous leukemia (CML). Clinically, CML is characterized by a chronic phase (CP) that eventually terminates into a blast cri
Publikováno v:
Europe PubMed Central
PML/RARalpha is the leukemogenetic protein of acute promyelocytic leukemia (APL). Treatment with retinoic acid (RA) induces degradation of PML/RARalpha, differentiation of leukaemic blasts, and disease remission. However, RA resistance arises during
Autor:
Jl, Cordell, Ka, Pulford, Bigerna B, Roncador G, Alison Banham, Colombo E, Pg, Pelicci, Dy, Mason, Falini B
Publikováno v:
Europe PubMed Central
In anaplastic large-cell lymphoma (ALCL), the (2;5) chromosomal translocation creates a fusion gene encoding the 80-kD NPM-ALK hybrid protein. This report describes three new monoclonal antibodies, two of which recognize, by Western blotting, the N-t
Autor:
Clara NERVI, Ff, Ferrara, Fanelli M, Rippo MR, Tomassini B, Pf, Ferrucci, Ruthardt M, Gelmetti V, Gambacorti-Passerini C, Diverio D, Grignani F, Pg, Pelicci, Testi R
Publikováno v:
Europe PubMed Central
All-trans-retinoic acid (RA) treatment induces morphological remission in acute promyelocytic leukemia (APL) patients carrying the t(15;17) and expressing the PML/RARalpha product by inducing terminal differentiation of the leukemic clone. RA treatme
Autor:
Pelicci G, Giordano S, Zhen Z, Ae, Salcini, Lanfrancone L, Alberto BARDELLI, Panayotou G, Md, Waterfield, Ponzetto C, Pg, Pelicci
Publikováno v:
University of Copenhagen
Europe PubMed Central
Europe PubMed Central
The receptor of Hepatocyte Growth Factor-Scatter Factor (HGF) is a tyrosine kinase which regulates cell motility and growth. After ligand-induced tyrosine phosphorylation, the HGF receptor associates with the Shc adaptor, via the SH2 domain. Site-dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8b5ff8f63c9890a5073f3abe38c29f8c
http://hdl.handle.net/2318/43169
http://hdl.handle.net/2318/43169
Autor:
Fagioli M, Grignani F, Pier Francesco Ferrucci, Alcalay M, Mencarelli A, Nicoletti I, Pg, Pelicci
Publikováno v:
Europe PubMed Central
Acute promyelocytic leukaemia is characterized by an expansion of haematopoietic precursors arrested at the promyelocytic stage (1). The differentiation block can be reversed by retinoic acid, which induces blast differentiation both in vitro (2) and
Autor:
Franco Aversa, Pg, Pelicci, Terenzi A, Carotti A, Felicini R, Mencarelli A, Donti E, Latini P, Aristei C, Mf, Martelli
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::62be8252fe696a942100772806324dfe
http://hdl.handle.net/11391/982186
http://hdl.handle.net/11391/982186
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
cDNA clones of the human c-fes mRNA were isolated. Nucleotide analysis showed that c-fes mRNA contains a 2514 nucleotide open reading frame, which could encode for a 93 kDa protein, and both 5' and 3' v-fes nonhomologous sequences. Primer extension e