Zobrazeno 1 - 10
of 1 074
pro vyhledávání: '"Pfmdr1"'
Autor:
Marcel Tapsou Baina, Jean Claude Djontu, Jacques Dollon Mbama Ntabi, Claujens Chastel Mfoutou Mapanguy, Abel Lissom, Christevy Jeannhey Vouvoungui, Reauchelvy Kamal Boumpoutou, Alain Maxime Mouanga, Etienne Nguimbi, Francine Ntoumi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to analyze polymorphisms in Pfcrt, Pfmdr1, and Pfk13 genes’ markers of resistance to Artemisinin-based combination therapy (ACT), in Plasmodium falciparum isolates from southern Brazzaville, 15 years after the adoption of
Externí odkaz:
https://doaj.org/article/669e5b0ce8164fd5b4ca1bb160480d7c
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Polymorphisms of Plasmodium falciparum chloroquine resistance transporter (pfcrt), Plasmodium falciparum multi-drug resistance 1 (pfmdr1) and Plasmodium falciparum kelch 13-propeller (pfk13) genes are accepted as valid molecular m
Externí odkaz:
https://doaj.org/article/53527f220475407e92c4a4255cbb2391
Autor:
Catherine Bakari, Celine I. Mandara, Rashid A. Madebe, Misago D. Seth, Billy Ngasala, Erasmus Kamugisha, Maimuna Ahmed, Filbert Francis, Samwel Bushukatale, Mercy Chiduo, Twilumba Makene, Abdunoor M. Kabanywanyi, Muhidin K. Mahende, Reginald A. Kavishe, Florida Muro, Sigsbert Mkude, Renata Mandike, Fabrizio Molteni, Frank Chacky, Dunstan R. Bishanga, Ritha J. A. Njau, Marian Warsame, Bilali Kabula, Ssanyu S. Nyinondi, Naomi W. Lucchi, Eldin Talundzic, Meera Venkatesan, Leah F. Moriarty, Naomi Serbantez, Chonge Kitojo, Erik J. Reaves, Eric S. Halsey, Ally Mohamed, Venkatachalam Udhayakumar, Deus S. Ishengoma
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Therapeutic efficacy studies (TESs) and detection of molecular markers of drug resistance are recommended by the World Health Organization (WHO) to monitor the efficacy of artemisinin-based combination therapy (ACT). This study as
Externí odkaz:
https://doaj.org/article/bbdfbdb13b094de59208ee4c4414aa68
Publikováno v:
Infection and Drug Resistance, Vol Volume 17, Pp 221-227 (2024)
Abdalmoneim M Magboul,1 Bakri YM Nour,2 Abdelhakam G Tamomh,1 Rashad Abdul-Ghani,3,4 Sayed Mustafa Albushra,5 Hanan Babiker Eltahir6 1Department of Parasitology & Medical Entomology, Faculty of Medical Laboratory Sciences, University of El Imam El Ma
Externí odkaz:
https://doaj.org/article/21615307555d41df8a5f831043da06ba
Autor:
Amélé Nyedzie Wotodjo, Mary Aigbiremo Oboh, Souleymane Doucoure, Nafissatou Diagne, Fatoumata Diène-Sarr, Makhtar Niang, Jean-François Trape, Cheikh Sokhna, Alfred Amambua-Ngwa, Umberto D’Alessandro
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Background Thanks to the scale up of malaria control interventions, the malaria burden in Senegal has decreased substantially to the point that the National Malaria Control Programme plans to achieve malaria elimination by 2030. To guide suc
Externí odkaz:
https://doaj.org/article/884a5303a43043fc93cdfd8d8fd480ed
Autor:
Akansha Singh, Mrigendra P. Singh, Nazia Anwar Ali, Rajan Poriya, Harsh Rajvanshi, Sekh Nisar, Sneha Bhandari, Ram S. Sahu, Himanshu Jayswar, Ashok K. Mishra, Aparup Das, Harpreet Kaur, Anup R. Anvikar, Ananias A Escalante, Altaf A. Lal, Praveen K. Bharti
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background Resistance against artemisinin-based combination therapy is one of the challenges to malaria control and elimination globally. Mutations in different genes (Pfdhfr, Pfdhps, Pfk-13 and Pfmdr1) confer resistance to artesunate and su
Externí odkaz:
https://doaj.org/article/ec227102454446539466b1b27a96e424
Autor:
Farindira Vesti Rahmasari, Puji Budi Setia Asih, Ismail Ekoprayitno Rozi, Suradi Wangsamuda, Rifqi Risandi, Farahana Kresno Dewayanti, Dendi Hadi Permana, Lepa Syahrani, Helen Dewi Prameswari, Herdiana H. Basri, Maria Dorina G. Bustos, Prakaykaew Charunwatthana, Arjen M. Dondorp, Mallika Imwong, Din Syafruddin
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Background Dihydroartemisinin–piperaquine has been Indonesia’s first-line anti-malarial treatment since 2008. Annual therapeutic efficacy studies (TES) done in the last 12 years showed continued high treatment efficacy in uncomplicated P
Externí odkaz:
https://doaj.org/article/c6c5b3f6576744daad7a9eef6a723677
Autor:
Mainga Hamaluba, Juliana Wambua, Arjen M. Dondorp, Jennifer Musyoki, Caroline Ngetsa, Oksana Kharabora, Leonard Ndwiga, Zaydah de Laurent, Kevin Wamae, Kelvin Kimenyi, Gabriel Mwambingu, Peter Kalume, Philip Bejon, Jeffrey Bailey, Rob van der Pluijm, Lynette Ochola-Oyier, Jonathan Juliano, Victor Osoti
Publikováno v:
Wellcome Open Research, Vol 7 (2024)
Introduction Antimalarial therapeutic efficacy studies are routinely conducted in malaria-endemic countries to assess the effectiveness of antimalarial treatment strategies. Targeted amplicon sequencing (AmpSeq) uniquely identifies and quantifies gen
Externí odkaz:
https://doaj.org/article/54f1bc978ccb46b1ae6ec30ff6a0a2bd
Autor:
Geletta Tadele, Aminata Jawara, Mary Oboh, Eniyou Oriero, Sisay Dugassa, Alfred Amambua-Ngwa, Lemu Golassa
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background Pfcrt gene has been associated with chloroquine resistance and the pfmdr1 gene can alter malaria parasite susceptibility to lumefantrine, mefloquine, and chloroquine. In the absence of chloroquine (CQ) and extensive use of artemet
Externí odkaz:
https://doaj.org/article/b767154908934c0ca0f7e3c9d0dbc84b
Autor:
Mainga Hamaluba, Juliana Wambua, Arjen M. Dondorp, Jennifer Musyoki, Caroline Ngetsa, Oksana Kharabora, Leonard Ndwiga, Zaydah de Laurent, Kevin Wamae, Kelvin Kimenyi, Gabriel Mwambingu, Peter Kalume, Philip Bejon, Jeffrey Bailey, Rob van der Pluijm, Lynette Ochola-Oyier, Jonathan Juliano, Victor Osoti
Publikováno v:
Wellcome Open Research, Vol 7 (2023)
Introduction Antimalarial therapeutic efficacy studies are routinely conducted in malaria-endemic countries to assess the effectiveness of antimalarial treatment strategies. Targeted amplicon sequencing (AmpSeq) uniquely identifies and quantifies gen
Externí odkaz:
https://doaj.org/article/7c572512032142968047eeeffce301e6