Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity

Autor: Pfister, Simona P., Schären, Olivier P., Beldi, Luca, Printz, Andrea, Notter, Matheus D., Mukherjee, Mohana, Li, Hai, Limenitakis, Julien P., Werren, Joel P., Tandon, Disha, Cuenca, Miguelangel, Hagemann, Stefanie, Uster, Stephanie S., Terrazos, Miguel A., Gomez de Agüero, Mercedes, Schürch, Christian M., Coelho, Fernanda M., Curtiss, Roy, Slack, Emma, Balmer, Maria L., Hapfelmeier, Siegfried

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Pfister, Simona; Schären, Olivier P.; Beldi, Luca; Printz, Andrea; Notter, Matheus D.; Mukherjee, Mohana; Li, Hai; Limenitakis, Julien P.; Werren, Joel P.; Tandon, Disha; Cuenca Vera, Miguelangel; Hagemann, Stefanie Claudia; Uster, Stephanie S.; Terrazos, Miguel A.; Gomez de Agüero, Mercedes; Schürch, Christian M.; Matos Coelho, Fernanda; Curtiss, Roy; Slack, Emma; Balmer, Maria L.; ... (2020). Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity. Nature Communications, 11(1), p. 1978. Springer Nature 10.1038/s41467-020-15891-9
Nature Communications
Nature Communications, 11 (1)

There is the notion that infection with a virulent intestinal pathogen induces generally stronger mucosal adaptive immunity than the exposure to an avirulent strain. Whether the associated mucosal inflammation is important or redundant for effective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acff1aa335d4ec009e795257b0980b1
https://doaj.org/article/a504641b48c641b380390cd26e0b3e02

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D-Alanine-Controlled Transient Intestinal Mono-Colonization with Non-Laboratory-Adapted Commensal E. coli Strain HS

Autor: Cuenca, Miguelangel, Pfister, Simona P., Buschor, Stefanie, Bayramova, Firuza, Hernandez, Sara B., Cava, Felipe, Kuru, Erkin, Van Nieuwenhze, Michael S., Brun, Yves V., Coelho, Fernanda M., Hapfelmeier, Siegfried

Soon after birth the mammalian gut microbiota forms a permanent and collectively highly resilient consortium. There is currently no robust method for re-deriving an already microbially colonized individual again-germ-free. We previously developed the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::658796ea04594448a34c7a33e7be1364