Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients – the study design of the LIBERAL-Trial

Autor: Meybohm, Patrick, Lindau, Simone, Treskatsch, Sascha, Francis, Roland, Spies, Claudia, Velten, Markus, Wittmann, Maria, Gueresir, Erdem, Stoppe, Christian, Kowark, Ana, Coburn, Mark, Selleng, Sixten, Baschin, Marcel, Jenichen, Gregor, Meersch, Melanie, Ermert, Thomas, Zarbock, Alexander, Kranke, Peter, Kredel, Markus, Helf, Antonia, Laufenberg-Feldmann, Rita, Ferner, Marion, Wittenmeier, Eva, Gürtler, Karl-Heinz, Kienbaum, Peter, De Abreu, Marcel Gama, Sander, Michael, Bauer, Michael, Seyfried, Timo, Gruenewald, Matthias, Choorapoikayil, Suma, Mueller, Markus M., Seifried, Erhard, Brosteanu, Oana, Bogatsch, Holger, Hasenclever, Dirk, Zacharowski, Kai, LIBERAL Collaboration Group, Baron, David, Grottke, Oliver, Hill, Aileen, Van Waesberghe, Julia, Ziemann, Sebastian, Tingart, Markus, Van Essen, Julius, Spring, Oliver, Pirzer, Raphael, Jaschinski, Ulrich, Heller, Axel R., Ertmer, Martin, Falk, Elke, Pickerodt, Philipp, Schiemann, Alexander, Schmidt, Katrin, Tafelski, Sascha, Trauzeddel, Ralf-Felix, Perka, Carsten, Ehrentraut, Heide, Fingehut, Louise, Hopf, Andreas, Guttenthaler, Vera, Neumann, Claudia, Osberghaus, Isabelle, Schuss, Patrick, Winkler, Anja, Kohlhof, Hendrik, Wirtz, Dieter C., Kalb, Robert, Hinterberg, Jonas, Schäfer, Maximilian, Koch, Thea, Piekarski, Florian, Tanner, Linda, Berg, Kira, Wiedenbeck, Carolin, Maushagen, Isabell, Zeisset, Daniela, Fuellenbach, Christoph, Westphal, Sabine, Pfeiffer, Sophia, Schnitzbauer, Andreas, Marzi, Ingo, Becker, Andreas, Ghanaati, Shahram, Schmitz-Rixen, Thomas, Brixner, Verena, Geisen, Christof, Herrmann, Eva, Edinger, Fabian, Koch, Christian, Kunzemann, Christian, Leicht, Dominik, Markmann, Melanie, Ruhrmann, Sophie, Schneck, Emanuel, Schulte, Dargmar, Gründling, Matthias, Brenig, Iris, Gerber, Manuela, Selleng, Kathleen, Wodrig, Sandra, Bloos, Frank, Bloos, Petra, Haucke, Anja, Knuhr-Kohlberg, Karina, Kolanos, Steffi, Schwope, Katrin, Thomas, Daniel, Buchholz, Corinna, Heller, Birte, Renner, Jochen, Schulz-Ruhtenberg, Nina, Elke, Gunnar, Fischer, Susanne, Hofbauer, Sabine, Straub, Peter, Zimmer, Sophie, Küllmar, Mira, Rosenow, Nadine, Massoth, Christina, Weiss, Raphael, Bitzinger, Diane, Pfister, Karin, Guzman, Ines, Kranke, Eva-Maria, Roewer, Norbert, Woeckel, Achim, Helmer, Philipp

Publikováno v: Trials 20(1), 101 (2019). doi:10.1186/s13063-019-3200-3
Trials, Vol 20, Iss 1, Pp 1-10 (2019)
Trials

Background Perioperative anaemia leads to impaired oxygen supply with a risk of vital organ ischaemia. In healthy and fit individuals, anaemia can be compensated by several mechanisms. Elderly patients, however, have less compensatory mechanisms beca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22c41068cafceebd9dd7975d54f0a7a
https://doi.org/10.21203/rs.2.55/v3