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Novel Uveal Melanoma Patient-Derived Organoid Models Recapitulate Human Disease to Support Translational Research.

Autor: Dalvin LA; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States.; Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota, United States.; School of Medicine, Deakin University, Geelong, Victoria, Australia.; Institute for Mental and Physical Health and Clinical Translation (IMPACT), Deakin University, Geelong, Victoria, Australia., Andrews-Pfannkoch CM; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Miley DR; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Hogenson TL; Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota, United States., Erickson SA; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Malpotra S; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Anderson KJ; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Omer ME; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Almada LL; Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota, United States., Zhang C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States., Li H; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, United States., Salomao DR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States., Shields CL; Wills Eye Hospital, Philadelphia, Pennsylvania, United States., Lally SE; Wills Eye Hospital, Philadelphia, Pennsylvania, United States., Malsch RM; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Armitage JA; School of Medicine, Deakin University, Geelong, Victoria, Australia.; Institute for Mental and Physical Health and Clinical Translation (IMPACT), Deakin University, Geelong, Victoria, Australia., Holmes HL; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States., Romero MF; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States., Fautsch MP; Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States., Markovic SN; Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota, United States.; Department of Immunology, Mayo Clinic, Rochester, Minnesota, United States., Fernandez-Zapico ME; Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota, United States.

Publikováno v: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2024 Nov 04; Vol. 65 (13), pp. 60.