Zobrazeno 1 - 10 of 25 pro vyhledávání: '"PfENR"'
1
Akademický článek
Structure-Based Design and Pharmacophore-Based Virtual Screening of Combinatorial Library of Triclosan Analogues Active against Enoyl-Acyl Carrier Protein Reductase of Plasmodium falciparum with Favourable ADME Profiles
Autor: Cecile Bieri, Akori Esmel, Melalie Keita, Luc Calvin Owono Owono, Brice Dali, Eugene Megnassan, Stanislav Miertus, Vladimir Frecer
Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 8, p 6916 (2023)
Cost-effective therapy of neglected and tropical diseases such as malaria requires everlasting drug discovery efforts due to the rapidly emerging drug resistance of the plasmodium parasite. We have carried out computational design of new inhibitors o
Externí odkaz: https://doaj.org/article/911538bdf4a743fa8e8eccac0ceb914e
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2
Akademický článek
The Performance of a Molecular Dynamics Simulation for the Plasmodium falciparum Enoyl-acyl carrier-protein Reductase Enzyme using Amber and GTX 780 and 970 Double Graphical Processing Units
Autor: Heru Suhartanto, Arry Yanuar, Ari Wibisono, Denny Hermawan, Alhadi Bustamam
Publikováno v: International Journal of Technology, Vol 9, Iss 1, Pp 150-158 (2018)
The invention of graphical processing units (GPUs) has significantly improved the speed of long processes used in molecular dynamics (MD) to search for drug candidates to treat diseases, such as malaria. Previous work using a single GTX GPU showed co
Externí odkaz: https://doaj.org/article/94ba4070c59b47e68fcc176ca90cbca4
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3
Akademický článek
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4
Kniha
Structural determination of triclosan derivatives as inhibitors of Plasmodium falciparum enoyl reductase (PfENR)
Autor: Lucumi Moreno, Edinson
Malaria is a disease that causes more than 1 million deaths per year world wide and more than 400 million clinical cases. Due to the acquired resistance of Plasmodium falciparum to the drugs used to control the infection, searching for new anti-malar
Externí odkaz: http://hdl.handle.net/1969.1/4742
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5
Identification of Flavonoids as Inhibitors of Plasmodium falciparum Enoyl-ACP Reductase by Hierarchical Virtual Screening
Autor: Larissa de Mattos Oliveira, Diego Mota da Costa, Aníbal de Freitas Santos Jr., Dayse A. A. Silva, Manoelito C. dos Santos Jr., Clayton Q. Alves, Hugo Neves Brandão
Publikováno v: Journal of the Brazilian Chemical Society v.31 n.12 2020
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Journal of the Brazilian Chemical Society, Volume: 31, Issue: 12, Pages: 2544-2552, Published: 14 DEC 2020
Malaria, a parasitic infection caused by Plasmodium falciparum, is a serious global public health problem. The enzyme enoyl-acyl carrier protein (ACP) reductase present in a limiting step in the biosynthesis of fatty acids type II was used to search
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fbb67f40b33bac70c0b6ff143a6c3a
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020001202544
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6
The Performance of a Molecular Dynamics Simulation for the Plasmodium falciparum Enoyl-acyl carrier-protein Reductase Enzyme using Amber and GTX 780 and 970 Double Graphical Processing Units
Autor: Ari Wibisono, Denny Hermawan, Arry Yanuar, Alhadi Bustamam, Heru Suhartanto
Publikováno v: International Journal of Technology, Vol 9, Iss 1, Pp 150-158 (2018)
The invention of graphical processing units (GPUs) has significantly improved the speed of long processes used in molecular dynamics (MD) to search for drug candidates to treat diseases, such as malaria. Previous work using a single GTX GPU showed co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036b35a3ff4a51bdfb767f59e16eec29
http://ijtech.eng.ui.ac.id/article/view/1186
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7
Akademický článek
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8
Akademický článek
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9
Akademický článek
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10
Constituents From the Stem Bark of Cinnamomum zeylanicum Welw. (Lauraceae) and Their Inhibitory Activity Toward Plasmodium falciparum Enoyl-ACP Reductase Enzyme
Autor: Eric René Sieliatchom Nkanwen, , , , and, Maurice Ducret Awouafack, Jean Jules Kezetas Bankeu, Hippolyte Kamdem Wabo, Sufyan Awad Alkarim Mustafa, Muhammad Shaiq Ali, Marc Lamshöft, Muhammad Iqbal Choudhary, Michael Spiteller, Pierre Tane
Publikováno v: Records of Natural Products, Vol 7, Iss 4, Pp 296-301 (2013)
A trans cinnamic anhydride (1) isolated for the first time from a natural source, along with the known compounds: ferrulic acid (2), (E) p-hydroxy cinnamic acid (3), clovanediol (4), squalene (5), and α -bisabolene (6) were isolated from the stem ba
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::53f318b5f607057a8e8b2c10326fd6a8
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