Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Peyton J. Tebon"'
Autor:
Peyton J. Tebon, Bowen Wang, Alexander L. Markowitz, Ardalan Davarifar, Brandon L. Tsai, Patrycja Krawczuk, Alfredo E. Gonzalez, Sara Sartini, Graeme F. Murray, Huyen Thi Lam Nguyen, Nasrin Tavanaie, Thang L. Nguyen, Paul C. Boutros, Michael A. Teitell, Alice Soragni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract High throughput drug screening is an established approach to investigate tumor biology and identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not accurately reflect the biology of human tumors. More clini
Externí odkaz:
https://doaj.org/article/cdb49d87278049f08e97471afd0ff5af
Autor:
Bowen Wang, Peyton J. Tebon, Alexander L. Markowitz, Graeme F. Murray, Huyen Nguyen, Nasrin Tavanaie, Thang L. Nguyen, Paul C. Boutros, Alice Soragni, Michael A. Teitell
Publikováno v:
Interferometry XXI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::412ecbf686633a93704b7d0a26e08371
https://doi.org/10.1117/12.2632405
https://doi.org/10.1117/12.2632405
Autor:
Bowen Wang, Peyton J. Tebon, Alexander L. Markowitz, Graeme F. Murray, Huyen Thi Lam Nguyen, Nasrin Tavanaie, Thang L. Nguyen, Paul C. Boutros, Alice Soragni, Michael A. Teitell
Publikováno v:
Conference on Lasers and Electro-Optics.
We develop a method to apply a high-throughput quantitative phase imaging-based assay to functional biomass accumulation measurements of 3D tumor organoids with single-organoid resolution, and demonstrate its utility for drug screening and therapy se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e81719493e27d8579a78e020bc9a3fad
https://doi.org/10.1364/cleo_at.2022.atu5i.5
https://doi.org/10.1364/cleo_at.2022.atu5i.5
Autor:
Peyton J. Tebon, Bowen Wang, Alexander L. Markowitz, Ardalan Davarifar, Patrycja Krawczuk, Graeme Murray, Huyen Thi Lam Nguyen, Nasrin Tavanaie, Thang L. Nguyen, Paul C. Boutros, Michael A. Teitell, Alice Soragni
High-throughput drug screening is an established approach to investigate tumor biology and identify therapeutic leads. Traditional platforms for high-throughput screening use two-dimensional cultures of immortalized cell lines which do not accurately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ff57eb5b117e3bcd315fb7c927b6dbc
https://doi.org/10.1101/2021.10.03.462896
https://doi.org/10.1101/2021.10.03.462896
Autor:
Ahmad Al Shihabi, Peyton J. Tebon, Jomjit Chantharasamee, Huyen T. Nguyen, Sara Sartini, Ardalan Davarifar, Nasrin Tavanaie, Scott D. Nelson, Noah Federman, Jane Yanagawa, Alice Soragni
Publikováno v:
Cancer Research. 82:3078-3078
Bone and soft tissue sarcomas span a spectrum of over one hundred histologic subtypes. Developing clinical trials and identifying effective therapies remains a challenge given the rarity of these tumors and scarcity of available tumor models. Patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e36aaa25fd6d88d20ee51aa46b42d6d9
https://doi.org/10.1158/1538-7445.am2022-3078
https://doi.org/10.1158/1538-7445.am2022-3078
Autor:
Peyton J. Tebon, Bowen Wang, Alexander L. Markowitz, Graeme Murray, Ardalan Davarifar, Huyen T. Nguyen, Nasrin Tavanaie, Thang L. Nguyen, Paul C. Boutros, Michael A. Teitell, Alice Soragni
Publikováno v:
Cancer Research. 82:3081-3081
As interest grows in using tumor organoids as models for drug discovery and precision medicine, platforms for the reliable functional testing and analysis of these organoids are needed. Existing functional approaches in precision medicine face diffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6c957409bc5d4c8dd914d81645d5cd
https://doi.org/10.1158/1538-7445.am2022-3081
https://doi.org/10.1158/1538-7445.am2022-3081
Autor:
Peyton J Tebon, Alice Soragni
Publikováno v:
Molecular Cancer Therapeutics. 20:LBA012-LBA012
Several anti-cancer compounds, including chemotherapy and targeted agents such as ifosfamide, cyclophosphamide, and imatinib, are administered as prodrugs which are metabolized to become pharmacologically active. Prodrugs are particularly difficult t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab43d37a6fa83673bf647beffc5a5115
https://doi.org/10.1158/1535-7163.targ-21-lba012
https://doi.org/10.1158/1535-7163.targ-21-lba012