Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Peyman Tavassoli"'
Autor:
Brian D. Robinson, Panagiotis J. Vlachostergios, Bhavneet Bhinder, Weisi Liu, Kailyn Li, Tyler J. Moss, Rohan Bareja, Kyung Park, Peyman Tavassoli, Joanna Cyrta, Scott T. Tagawa, David M. Nanus, Himisha Beltran, Ana M. Molina, Francesca Khani, Juan Miguel Mosquera, Evanguelos Xylinas, Shahrokh F. Shariat, Douglas S. Scherr, Mark A. Rubin, Seth P. Lerner, Surena F. Matin, Olivier Elemento, Bishoy M. Faltas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Upper tract urothelial carcinoma (UTUC) is an aggressive cancer and largely uncharacterised cancer. Here, Faltas and colleagues report its distinctive molecular and immune landscape compared to urothelial carcinoma of the bladder and explore the role
Externí odkaz:
https://doaj.org/article/1c54e7d3caaa498c865d65f8cebe16d4
Publikováno v:
Case Reports in Urology, Vol 2012 (2012)
A. schaalii is a rare uropathogen. We report urosepsis with Actinobaculum schaalii detected serendipitously in blood and urine culture in a 79-year-old with urinary tract obstruction. This paper illuminates the flaws in our current system in detectin
Externí odkaz:
https://doaj.org/article/2c8f7c5f442f4e1fbc097dedf1e34ae9
Autor:
Artem Cherkasov, Paul S. Rennie, Emma Tomlinson Guns, Helge Prinz, Konrad J. Böhm, Hans Adomat, Kriti Singh, Kate Frewin, Natalia Kanaan, Peyman Tavassoli, Eric Leblanc, Peter Axerio-Cilies, Nathan A. Lack, Mohamed D.H. Hassona, Huifang Li
PDF file, 162K, AR mRNA levels are unaffected upon treatment with VPC-3022 and VPC-3033. Total RNA was extracted after treatment of LNCaP and MDV3100-resistant cells with VPC-3022 and VPC-3033 for 24 hours at the indicated concentrations in the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0406c04cd1febb6f269dbf52c712dfe4
https://doi.org/10.1158/1535-7163.22499370.v1
https://doi.org/10.1158/1535-7163.22499370.v1
Autor:
Artem Cherkasov, Paul S. Rennie, Emma Tomlinson Guns, Helge Prinz, Konrad J. Böhm, Hans Adomat, Kriti Singh, Kate Frewin, Natalia Kanaan, Peyman Tavassoli, Eric Leblanc, Peter Axerio-Cilies, Nathan A. Lack, Mohamed D.H. Hassona, Huifang Li
PDF file, 122K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3aed416d5740000364665d25954a263
https://doi.org/10.1158/1535-7163.22499358.v1
https://doi.org/10.1158/1535-7163.22499358.v1
Autor:
Artem Cherkasov, Paul S. Rennie, Emma Tomlinson Guns, Helge Prinz, Konrad J. Böhm, Hans Adomat, Kriti Singh, Kate Frewin, Natalia Kanaan, Peyman Tavassoli, Eric Leblanc, Peter Axerio-Cilies, Nathan A. Lack, Mohamed D.H. Hassona, Huifang Li
PDF file, 2136K, (A) Effect of VPC-3022 on AR activity in HeLa-AR cells in the presence of cyclohexamide. HeLa-AR cells were treated with serially-diluted concentrations of VPC-3022 (0 - 100 ?M) with or without 10 ?M of cyclohexamide for 8 hours, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14071971750f52e50a971a94974714b0
https://doi.org/10.1158/1535-7163.22499367.v1
https://doi.org/10.1158/1535-7163.22499367.v1
Autor:
Artem Cherkasov, Paul S. Rennie, Emma Tomlinson Guns, Helge Prinz, Konrad J. Böhm, Hans Adomat, Kriti Singh, Kate Frewin, Natalia Kanaan, Peyman Tavassoli, Eric Leblanc, Peter Axerio-Cilies, Nathan A. Lack, Mohamed D.H. Hassona, Huifang Li
PDF file, 1976K, (A) Inhibition of in vitro polymerization of tubulin at 37 {degree sign}C by various concentrations of VPC-3033; turbidity was recorded at 360 nM.The steady-state tubulin assembly level in the absence of inhibitor was set at 100%. (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d188b9669c9362a95eae66c4df6dfc18
https://doi.org/10.1158/1535-7163.22499361
https://doi.org/10.1158/1535-7163.22499361
Autor:
Artem Cherkasov, Paul S. Rennie, Emma Tomlinson Guns, Helge Prinz, Konrad J. Böhm, Hans Adomat, Kriti Singh, Kate Frewin, Natalia Kanaan, Peyman Tavassoli, Eric Leblanc, Peter Axerio-Cilies, Nathan A. Lack, Mohamed D.H. Hassona, Huifang Li
PDF file, 3480K, The binding pose of DHT (A) and VPC-3022 with AR by molecular docking (B) and binding pose of VPC-3022 with AR after 10 ns molecular dynamics (C); RMSD values of the protein backbone, protein-ligand, ligand in the 10 ns molecular dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aa3c1da8ca184de04da05a59d985aa
https://doi.org/10.1158/1535-7163.22499364
https://doi.org/10.1158/1535-7163.22499364
Autor:
Artem Cherkasov, Paul S. Rennie, Emma Tomlinson Guns, Helge Prinz, Konrad J. Böhm, Hans Adomat, Kriti Singh, Kate Frewin, Natalia Kanaan, Peyman Tavassoli, Eric Leblanc, Peter Axerio-Cilies, Nathan A. Lack, Mohamed D.H. Hassona, Huifang Li
The human androgen receptor plays a major role in the development and progression of prostate cancer and represents a well-established drug target. All clinically approved androgen receptor antagonists possess similar chemical structures and exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b77f02358c43c74ce57845da551d74
https://doi.org/10.1158/1535-7163.c.6536130.v1
https://doi.org/10.1158/1535-7163.c.6536130.v1
Autor:
Artem Cherkasov, Paul S. Rennie, Emma Tomlinson Guns, Helge Prinz, Konrad J. Böhm, Hans Adomat, Kriti Singh, Kate Frewin, Natalia Kanaan, Peyman Tavassoli, Eric Leblanc, Peter Axerio-Cilies, Nathan A. Lack, Mohamed D.H. Hassona, Huifang Li
PDF file, 109K, Inhibition of VPC-3022 against wild-type AR in HeLa-AR cells. HeLa-AR cells transfected with ARR3tk-luciferase reporter were treated with VPC-3022 for 24 hours in various concentrations in the presence of 0.1 nM R1881. Error bars indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2753eee2829568689bdd1b107cc06191
https://doi.org/10.1158/1535-7163.22499373.v1
https://doi.org/10.1158/1535-7163.22499373.v1
Publikováno v:
Pathology, research and practice. 216(3)
The long-term risk of secondary malignancy is a potential late effect of brachytherapy. However, the time interval, anatomic site and histopathology are not well studied. We sought to characterize the bladder cancers that developed following treatmen