Assessing the Perturbing Effects of Drugs on Lipid Bilayers Using Gramicidin Channel-Based In Silico and In Vitro Assays.

Autor: Sun D; Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States., Peyear TA; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York 10065, United States., Bennett WFD; Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States., Holcomb M; Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States., He S; Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States., Zhu F; Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States., Lightstone FC; Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States., Andersen OS; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, New York 10065, United States., Ingólfsson HI; Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Oct 22; Vol. 63 (20), pp. 11809-11818. Date of Electronic Publication: 2020 Oct 01.

Gramicidin Increases Lipid Flip-Flop in Symmetric and Asymmetric Lipid Vesicles.

Autor: Doktorova M; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medical College, New York, New York. Electronic address: milka.n.doktorova@uth.tmc.edu., Heberle FA; Department of Integrative Biology and Pharmacology, University of Texas Health Science Center, Houston, Texas; The Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee, Knoxville, Tennessee., Marquardt D; University of Windsor, Ontario, Canada., Rusinova R; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York., Sanford RL; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York., Peyear TA; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York., Katsaras J; Large Scale Structures Group, Oak Ridge National Laboratory, Oak Ridge, Tennessee, Oak Ridge National Laboratory, Oak Ridge, Tennessee; Shull Wollan Center, Oak Ridge National Laboratory, Oak Ridge, Tennessee., Feigenson GW; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York., Weinstein H; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Greenberg Center, New York, New York., Andersen OS; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York.

Publikováno v: Biophysical journal [Biophys J] 2019 Mar 05; Vol. 116 (5), pp. 860-873. Date of Electronic Publication: 2019 Jan 25.

Sertraline modulates hippocampal plasticity via sigma 1 receptors, cellular stress and neurosteroids.

Autor: Izumi, Yukitoshi, Reiersen, Angela M., Lenze, Eric J., Mennerick, Steven J., Zorumski, Charles F.

Publikováno v: Translational Psychiatry; 11/21/2024, Vol. 14 Issue 1, p1-11, 11p

Cannabidiol increases gramicidin current in human embryonic kidney cells: An observational study.

Autor: Ghovanloo, Mohammad-Reza^1,2 (AUTHOR), Goodchild, Samuel J.¹ (AUTHOR), Ruben, Peter C.² (AUTHOR) pruben@sfu.ca

Publikováno v: PLoS ONE. 8/1/2022, Vol. 17 Issue 8, p1-8. 8p.

Selective Serotonin Reuptake Inhibitors within Cells: Temporal Resolution in Cytoplasm, Endoplasmic Reticulum, and Membrane.

Autor: Nichols, Aaron L., Blumenfeld, Zack, Luebbert, Laura, Knox, Hailey J., Muthusamy, Anand K., Marvin, Jonathan S., Kim, Charlene H., Grant, Stephen N., Walton, David P., Cohen, Bruce N., Hammar, Rebekkah, Looger, Loren, Artursson, Per, Dougherty, Dennis A., Lester, Henry A.

Publikováno v: Journal of Neuroscience; 3/29/2023, Vol. 43 Issue 13, p2222-2241, 20p