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pro vyhledávání: '"Pevzner, Pavel A"'
Autor:
Functional, Participants in a NIH Workshop on, Proteomics, Integrative, Johnson, Kristin E. Burnum, Conrads, Thomas P., Drake, Richard R., Herr, Amy E., Iyengar, Ravi, Kelly, Ryan T., Lundberg, Emma, MacCoss, Michael J., Naba, Alexandra, Nolan, Garry P., Pevzner, Pavel A., Rodland, Karin D., Sechi, Salvatore, Slavov, Nikolai, Spraggins, Jeffrey M., Van Eyk, Jennifer E., Vidal, Marc, Vogel, Christine, Walt, David R., Kelleher, Neil L.
All human diseases involve proteins, yet our current tools to characterize and quantify them are limited. To better elucidate proteins across space, time, and molecular composition, we provide provocative projections for technologies to meet the chal
Externí odkaz:
http://arxiv.org/abs/2108.07660
The problem of reconstructing a string from its error-prone copies, the trace reconstruction problem, was introduced by Vladimir Levenshtein two decades ago. While there has been considerable theoretical work on trace reconstruction, practical soluti
Externí odkaz:
http://arxiv.org/abs/2010.06083
Akademický článek
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Autor:
Safonova, Yana, Pevzner, Pavel A.
The V(D)J recombination forms the immunoglobulin genes by joining the variable (V), diversity (D), and joining (J) germline genes. Since variations in germline genes have been linked to various diseases, personalized immunogenomics aims at finding al
Externí odkaz:
http://arxiv.org/abs/1901.02483
Akademický článek
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Autor:
Shlemov, Alexander, Bankevich, Sergey, Bzikadze, Andrey, Turchaninova, Maria A., Safonova, Yana, Pevzner, Pavel A.
Transforming error-prone immunosequencing datasets into antibody repertoires is a fundamental problem in immunogenomics, and a prerequisite for studies of immune responses. Although various repertoire reconstruction algorithms were released in the la
Externí odkaz:
http://arxiv.org/abs/1704.07184
While metagenomics has emerged as a technology of choice for analyzing bacterial populations, assembly of metagenomic data remains difficult thus stifling biological discoveries. metaSPAdes is a new assembler that addresses the challenge of metagenom
Externí odkaz:
http://arxiv.org/abs/1604.03071
Recent advances in top-down mass spectrometry enabled identification of intact proteins, but this technology still faces challenges. For example, top-down mass spectrometry suffers from a lack of sensitivity since the ion counts for a single fragment
Externí odkaz:
http://arxiv.org/abs/1604.02270
Autor:
Alekseyev, Max A., Pevzner, Pavel A.
Publikováno v:
Lecture Notes in Computer Science 6398 (2010), pp. 198-215
An important question in genome evolution is whether there exist fragile regions (rearrangement hotspots) where chromosomal rearrangements are happening over and over again. Although nearly all recent studies supported the existence of fragile region
Externí odkaz:
http://arxiv.org/abs/1011.0200