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Molecular determinants of phospholipid treatment to reduce intracellular cholesterol accumulation in NPC1 deficiency.

Autor: Deng S; Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA., Liu TA; Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA., Ilnytska O; Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA., Allada T; Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA., Fomina A; Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA., Lin N; Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA., Petukhova VZ; Department of Chemistry, University of Illinois Chicago, Chicago, Illinois, USA., Pathmasiri KC; Department of Chemistry, University of Illinois Chicago, Chicago, Illinois, USA., Chinthapally K; Warren Center for Drug Discovery and Development, and Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA., Blagg BSJ; Warren Center for Drug Discovery and Development, and Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA., Ashfeld BL; Warren Center for Drug Discovery and Development, and Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA., Cologna SM; Department of Chemistry, University of Illinois Chicago, Chicago, Illinois, USA., Storch J; Department of Nutritional Sciences, Rutgers University, New Brunswick, New Jersey, USA; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey, USA. Electronic address: storch@sebs.rutgers.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 Nov; Vol. 300 (11), pp. 107889. Date of Electronic Publication: 2024 Oct 11.

Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.

Autor: Petukhova VZ; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Aboagye SY; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA., Ardini M; Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Lullo RP; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA., Fata F; Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Byrne ME; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA., Gabriele F; Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Martin LM; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA., Harding LNM; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Gone V; UICentre, Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Dangi B; Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Lantvit DD; UICentre, Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Nikolic D; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Ippoliti R; Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy., Effantin G; University of Grenoble Alpes, CEA, CNRS, IBS, F-38000, Grenoble, France., Ling WL; University of Grenoble Alpes, CEA, CNRS, IBS, F-38000, Grenoble, France., Johnson JJ; Department of Pharmacy Practice, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA., Thatcher GRJ; Department of Pharmacology & Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ, USA., Angelucci F; Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy. francesco.angelucci@univaq.it., Williams DL; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL, USA. david_williams@rush.edu., Petukhov PA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, USA. pap4@uic.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Jun 22; Vol. 14 (1), pp. 3737. Date of Electronic Publication: 2023 Jun 22.

Whole Cell MALDI Fingerprinting Is a Robust Tool for Differential Profiling of Two-Component Mammalian Cell Mixtures.

Autor: Petukhova VZ; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S Wood St., MC 781, Room 539, Chicago, IL, 60612, USA., Young AN; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S Wood St., MC 781, Room 539, Chicago, IL, 60612, USA., Wang J; Ometa Labs, 3210 Merryfield Row, San Diego, CA, 92121, USA., Wang M; Ometa Labs, 3210 Merryfield Row, San Diego, CA, 92121, USA., Ladanyi A; Department of Obstetrics & Gynecology, Rush University Medical Center, 1653 W Congress Pkwy, Chicago, IL, 60612, USA., Kothari R; Department of Obstetrics & Gynecology-Division of Gynecologic Oncology, University of Illinois at Chicago, 820 S Wood St., Chicago, IL, 60612, USA., Burdette JE; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S Wood St., MC 781, Room 539, Chicago, IL, 60612, USA., Sanchez LM; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 S Wood St., MC 781, Room 539, Chicago, IL, 60612, USA. sanchelm@uic.edu.

Publikováno v: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2019 Feb; Vol. 30 (2), pp. 344-354. Date of Electronic Publication: 2018 Oct 23.