Boron Neutron Capture Therapy in the Treatment of Locally Recurred Head-and-Neck Cancer: Final Analysis of a Phase I/II Trial

Autor: Tiina Seppälä, Timo Atula, Sauli Savolainen, Hanna Koivunoro, Kauko Saarilahti, Heikki Minn, Eero Salli, Leena Kankaanranta, Iiro Auterinen, Mauri Kouri, Tom Serén, Petri Kotiluoto, Jouni Uusi-Simola, Juhani Collan, Mika Kortesniemi, Heikki Joensuu, Marko Seppänen, Antti Mäkitie, Hannu Revitzer, Petteri Välimäki

Publikováno v: Kankaanranta, L, Seppälä, T, Koivunoro, H, Saarilahti, K, Atula, T, Collan, J, Salli, E, Kortesniemi, M, Uusi-Simola, J, Välimäki, P, Mäkitie, A, Seppänen, M, Minn, H, Revitzer, H, Kouri, M, Kotiluoto, P, Seren, T, Auterinen, I, Savolainen, S & Joensuu, H 2012, ' Boron neutron capture therapy in the treatment of locally recurred head-and-neck cancer : Final analysis of a phase I/II trial ', International Journal of Radiation Oncology Biology Physics, vol. 82, no. 1, pp. e67-e75 . https://doi.org/10.1016/j.ijrobp.2010.09.057

Purpose To investigate the efficacy and safety of boron neutron capture therapy (BNCT) in the treatment of inoperable head-and-neck cancers that recur locally after conventional photon radiation therapy. Methods and Materials In this prospective, sin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3707e46cc87bdbeed8374da588d79b
https://doi.org/10.1016/j.ijrobp.2010.09.057

Comparison of Different Cell-cluster Models for Cell-level Dosimetry

Autor: Antti Kuronen, J. Petteri Välimäki, Jiri Stepanek, Sami A. Ilvonen, Sauli Savolainen, Juha Lampinen

Publikováno v: Acta Oncologica. 40:92-97

An important factor in dose calculations for targeted radionuclide therapy is the cell-cluster model used. We developed a cell-cluster model based on optimization through mechanical hard-sphere collisions. The geometrical properties and the dosimetri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1269b24314c585c18c44d236dd9517
https://doi.org/10.1080/028418601750071136

Cluster Models in Cellular Level Electron Dose Calculations

Autor: Jiri Stepanek, Juha Lampinen, Sauli Savolainen, Petteri Välimäki, Antti Kuronen

Publikováno v: Acta Oncologica. 38:367-372

A program for calculating absorbed dose was developed for radioimmunotherapy (RIT) purposes. It was used to determine the difference in the therapeutic effect of (111)In electrons when using a close-packed cubic geometry and a cell cluster model deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fb48348ad9206fc6fa2994ae2e130d
https://doi.org/10.1080/028418699431456

Metamorphosis of a 35 year-old triga reactor into a modern BNCT facility

Autor: Petteri Välimäki, Carita Aschan, Mika Kortesniemi, Rolf Rosenberg, Sauli Savolainen, Seppo Salmenhaara, Matti Toivonen, Iiro Auterinen, Tom Serén, Kosunen A, Lampinen J, Tiina Seppälä, Vesa Tanner, Pekka Hiismäki, Petri Kotiluoto

Publikováno v: Frontiers in Neutron Capture Therapy ISBN: 9781461354789
Auterinen, I, Hiismäki, P, Kotiluoto, P, Rosenberg, R, Salmenhaara, S, Seppälä, T, Seren, T, Tanner, V, Aschan, C, Kortesniemi, M, Kosunen, A, Lampinen, J, Savolainen, S, Toivonen, M & Välimäki, P 2001, Metamorphosis of a 35 year-old triga reactor into a modern BNCT facility . in M F Hawthorne, K Shelly & R J Wiersema (eds), Frontiers in Neutron Capture Therapy . vol. 1, Springer, pp. 267-275 . https://doi.org/10.1007/978-1-4615-1285-1_36

Using FiR 1, a 250kW TRIGA reactor as a neutron source for BNCT was screened as a viable option in 1990, as the future of the reactor was questioned. By the initiative of the medical radio isotope group at VTT the Finnish BNCT project started incorpo

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https://doi.org/10.1007/978-1-4615-1285-1_36

The Finnish BNCT facility is ready for patients

Autor: Iiro Auterinen, Carita Aschan, Pekka Hiismäki, Mika Kortesniemi, Antti Kosunen, Petri Kotiluoto, Juha Lampinen, Rolf Rosenberg, Seppo Salmenhaara, Sauli Savolainen, Tiina Seppälä, Tom Seren, Vesa Tanner, Matti Toivonen, Petteri Välimäki

Publikováno v: Auterinen, I, Aschan, C, Hiismäki, P, Kortesniemi, M, Kosunen, A, Kotiluoto, P, Lampinen, J, Rosenberg, R, Salmenhaara, S, Savolainen, S, Seppälä, T, Seren, T, Tanner, V, Toivonen, M & Välimäki, P 1999, The Finnish BNCT facility is ready for patients . in M Lindberg & E Laine (eds), Proceedings of the XXXIII Annual Conference of the Finnish Physical Society : Abstracts ., 87.56.-v, 5.6, University of Turku, Turku, University of Turku: Department of Physical Sciences. Report L, no. L28, XXXIII Annual Conference of the Finnish Physical Society, Turku, Finland, 4/03/99 .
VTT Technical Research Centre of Finland-PURE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a4d61330ff5073aba941a956859f9f46
https://cris.vtt.fi/en/publications/d8ddbc26-6761-4e2e-94ad-69472e1651e0