Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Petter Vikman"'
Publikováno v:
Vascular Health and Risk Management, Vol 2009, Iss default, Pp 333-341 (2009)
Petter Vikman, Cang-Bao Xu, Lars EdvinssonDepartment of Clinical Sciences, Experimental Vascular Research, Lund, SwedenAims: Cigarette smoking is one of the strongest risk factors for stroke. However, the underlying molecular mechanisms that smoke le
Externí odkaz:
https://doaj.org/article/971f6c65d130432ab745540d1ef61c44
Autor:
Jiangming Sun, Yang De Marinis, Peter Osmark, Pratibha Singh, Annika Bagge, Bérengère Valtat, Petter Vikman, Peter Spégel, Hindrik Mulder
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164962 (2016)
RNA editing is a post-transcriptional alteration of RNA sequences that, via insertions, deletions or base substitutions, can affect protein structure as well as RNA and protein expression. Recently, it has been suggested that RNA editing may be more
Externí odkaz:
https://doaj.org/article/06f86d308cd74c9d86fcfc09592bffd8
Autor:
Emilia Ottosson-Laakso, Tiinamaija Tuomi, Björn Forsén, Monika Gullström, Per-Henrik Groop, Leif Groop, Petter Vikman
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146114 (2016)
Familial renal glycosuria is an inherited disorder resulting in glucose excretion in the urine despite normal blood glucose concentrations. It is most commonly due to mutations in the SLC5A2 gene coding for the glucose transporter SGLT2 in the proxim
Externí odkaz:
https://doaj.org/article/6be0505ec8af4ebbb483557638a421bf
Autor:
Emma Ahlqvist, Nikolay Oskolkov, Ola Hansson, Leif Groop, Petter Storm, Petter Vikman, Ulrika Krus, Emilia Ottosson-Laakso, Rashmi B. Prasad, João Fadista
Publikováno v:
Diabetes. 66:3013-3028
Dysregulation of gene expression in islets from patients with type 2 diabetes (T2D) might be causally involved in the development of hyperglycemia, or it could develop as a consequence of hyperglycemia (i.e., glucotoxicity). To separate the genes tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fa641c3515bbf069ddabb814c3afdf
https://doi.org/10.2337/db17-0311
https://doi.org/10.2337/db17-0311
Autor:
Panu K. Luukkonen, Jeremy M. Palmer, Taru Tukiainen, Marja Leivonen, Marju Orho-Melander, Hannele Yki-Järvinen, Adnan Ali, Johanna Arola, Petter Vikman, Leif Groop, Matej Orešič, Tuulia Hyötyläinen, Emma Scott, P.A. Nidhina Haridas, Vesa M. Olkkonen, Quentin M. Anstee, You Zhou, Anne Juuti, Linda Ahonen, Om Prakash Dwivedi
Publikováno v:
Journal of Hepatology
Background: Carriers of the transmembrane 6 superfamily member 2 E167K gene variant (TM6SF2(EK/KK)) have decreased expression of the TM6SF2 gene and increased risk of NAFLD and NASH. Unlike common 'obese/metabolic' NAFLD, these subjects lack hypertri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2105641af267468edb0495cd217c381c
https://doi.org/10.1016/j.jhep.2017.02.014
https://doi.org/10.1016/j.jhep.2017.02.014
Autor:
Petter Vikman, Mahboubeh Daneshpajooh, Madhusudhan Bysani, Charlotte Ling, Annika Bagge, Hindrik Mulder, Lena Eliasson, Emilia Ottosson Laakso, Karl Bacos
Publikováno v:
Diabetologia
Aims/hypothesis Pancreatic beta cell dysfunction is a prerequisite for the development of type 2 diabetes. Histone deacetylases (HDACs) may affect pancreatic endocrine function and glucose homeostasis through alterations in gene regulation. Our aim w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9c052a77578d3efc513b6fc84ac7a1
https://doi.org/10.1007/s00125-016-4113-2
https://doi.org/10.1007/s00125-016-4113-2
Autor:
João Fadista, Isabella Artner, Alexander Balhuizen, Nils Wierup, Hedvig Bennet, Inês G. Mollet, Anya Medina, Lena Eliasson, Marloes Dekker-Nitert, Emilia Ottosson-Laakso, Annika Bagge, Cecilia Nagorny, Petter Vikman, Malin Fex
Publikováno v:
Diabetologia. 59:744-754
The Gq-coupled 5-hydroxytryptamine 2B (5-HT2B) receptor is known to regulate the proliferation of islet beta cells during pregnancy. However, the role of serotonin in the control of insulin release is still controversial. The aim of the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acde60fc9ff6a0cb80d4212e33b5180
https://doi.org/10.1007/s00125-015-3847-6
https://doi.org/10.1007/s00125-015-3847-6
Autor:
Petter Vikman, Olga Göransson, Samuel W. Cushman, Björn Hansson, Karin G. Stenkula, Björn Morén, Vipul Periwal, Sebastian Wasserstrom, Petter Storm
Publikováno v:
J Mol Endocrinol
To capture immediate cellular changes during diet-induced expansion of adipocyte cell volume and number, we characterized mature adipocytes during a short-term high-fat diet (HFD) intervention. Male C57BL6/J mice were fed chow diet, and then switched
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5191cb30d877dfc8d863a0cfd15be65
https://pubmed.ncbi.nlm.nih.gov/29339400
https://pubmed.ncbi.nlm.nih.gov/29339400
Autor:
Tiinamaija Tuomi, Petter Vikman, Nael Shaat, Rashmi B. Prasad, Tom Forsén, Petter Storm, Mozhgan Dorkhan, Leif Groop, Annemari Käräjämäki, Kaj Lahti, Ylva Wessman, Anders Rosengren, Åke Lernmark, Annelie Carlsson, Ola Hansson, Ulf Malmqvist, Mats Martinell, Hindrik Mulder, Emma Ahlqvist, Eero Lindholm, Dina Mansour Aly, Peter Almgren, Peter Spégel, Olle Melander
Publikováno v:
The Lancet Diabetes & Endocrinology
Summary Background Diabetes is presently classified into two main forms, type 1 and type 2 diabetes, but type 2 diabetes in particular is highly heterogeneous. A refined classification could provide a powerful tool to individualise treatment regimens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b53c46bf688c76057b9c23f12b91c9
Autor:
Dina Mansour Aly, Anders Rosengren, Petter Vikman, Hindrik Mulder, Åke Lernmark, Ola Hansson, Peter Spégel, Eero Lindholm, Tom Forsén, Leif Groop, Emma Ahlqvist, Mozhgan Dorkhan, Peter Almgren, Petter Storm, Olle Melander, Rashmi B. Prasad, Kaj Lahti, Nael Shaat, Ylva Wessman, Annelie Carlsson, Tiinamaija Tuomi, Annemarie Käräjämäki, Ulf Malmqvist, Mats Martinell
BackgroundDiabetes is presently classified into two main forms, type 1 (T1D) and type 2 diabetes (T2D), but especially T2D is highly heterogeneous. A refined classification could provide a powerful tool individualize treatment regimes and identify in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756ed46cda2383bdbeb560c73ab69403
