Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Petter Russell C"'
Publikováno v:
In Current Opinion in Chemical Biology 2010 14(4):475-480
Autor:
Kluge, Arthur F, Petter, Russell C
Publikováno v:
In Current Opinion in Chemical Biology 2010 14(3):421-427
Autor:
Kiesman, William F., Zhao, Jin, Conlon, Patrick R., Petter, Russell C., Jin, Xiaowei, Smits, Glenn, Lutterodt, Frank, Sullivan, Gail W., Linden, Joel
Publikováno v:
In Bioorganic & Medicinal Chemistry 2006 14(11):3654-3661
Autor:
Kiesman, William F *, Petter, Russell C
Publikováno v:
In Tetrahedron: Asymmetry 2002 13(9):957-960
Autor:
Singh, Juswinder1 jsingh@avilatx.com, Petter, Russell C.1, Baillie, Thomas A.2, Whitty, Adrian3
Publikováno v:
Nature Reviews Drug Discovery. Apr2011, Vol. 10 Issue 4, p307-317. 11p. 1 Color Photograph, 2 Diagrams, 1 Chart, 2 Graphs.
Autor:
Fotsch, Christopher, Kumaravel, G., Sharma, Sushil K., Wu, Arthur D., Gounarides, John S., Nirmala, N.R., Petter, Russell C.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(15):2125-2130
Publikováno v:
The Journal of Organic Chemistry. 76:5074-5081
CBS-QB3 enthalpies of reaction have been computed for the conjugate additions of MeSH to six α,β-unsaturated ketones. Compared with addition to methyl vinyl ketone, the reaction becomes 1-3 kcal mol(-1) less exothermic when an α-Me, β-Me, or β-P
Publikováno v:
Synthetic Communications. 37:1267-1272
Dimethyl bicyclo[2.2.2]octane‐1,4‐dicarboxylate (4), a key starting material for a novel adenosine A1 receptor antagonist, was prepared in a one‐pot reaction with convenient workup and improved yield.
Autor:
Melissa Tam, Xiaowei Jin, Ko-Chung Lin, Jianbo Zhang, Patrick Conlon, Chi Vu, Liqing Chen, Glenn Smits, William F. Kiesman, Petter Russell C, Frank Lutterodt
Publikováno v:
Journal of Medicinal Chemistry. 49:7132-7139
Novel tricyclic imidazoline antagonists of the adenosine A1 receptor are described. For key compounds, the selectivity level over other adenosine receptor subtypes is examined along with their in vivo effects in a rat diuresis model. Compound 14, the
Autor:
Petter Russell C, Xiaowei Jin, Jin Zhao, Frank Lutterodt, William F. Kiesman, Patrick Conlon, Gail W. Sullivan, Joel Linden, Glenn Smits
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:3654-3661
During the search for second-generation adenosine A(1) receptor antagonist alternatives to the clinical candidate 8-(3-oxa-tricyclo[3.2.1.0(2,4)]oct-6-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione (BG9719), we developed a series of novel xanthines su