Výsledky vyhledávání - "Petter, Sjölin"

Modeling Strategies for Quantification of In Vivo 18F-AV-1451 Binding in Patients with Tau Pathology

Autor: Tomas G Olsson, Ruben Smith, Andreas Hahn, Maria Erlandsson, Olof Strandberg, G.M. James, Jonas Jögi, Douglas Hägerström, Martin Schain, Petter Sjölin, Oskar Hansson, Rupert Lanzenberger

Publikováno v: Journal of Nuclear Medicine. 58:623-631

Aggregation of hyperphosphorylated tau is a major hallmark of many neurodegenerative diseases, including Alzheimer disease (AD). In vivo imaging with PET may offer important insights into pathophysiologic mechanisms, diagnosis, and disease progressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7480d98603705f18a19e7f522adc872a
https://doi.org/10.2967/jnumed.116.174508

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Modeling Strategies for Quantification of In Vivo

Autor: Andreas, Hahn, Martin, Schain, Maria, Erlandsson, Petter, Sjölin, Gregory M, James, Olof T, Strandberg, Douglas, Hägerström, Rupert, Lanzenberger, Jonas, Jögi, Tomas G, Olsson, Ruben, Smith, Oskar, Hansson

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b8df1021b4dc8d95757a845af30dff5d
https://pubmed.ncbi.nlm.nih.gov/27765859

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Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite

Autor: Bengt-Olof Axelsson, Petter Sjölin, David S. Silberstein, Kristina Lexmüller, Anna Miller-Larsson, Helena Gullstrand, Solange H Korn

Publikováno v: Drug Metabolism and Disposition. 35:1788-1796

The airway retention of inhaled glucocorticosteroids (GCs) depends largely on their lipophilicity. Inhaled budesonide (BUD) becomes highly lipophilic reversibly by the formation of esters acting as a reservoir of active BUD. Ciclesonide (CIC) was als

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e82a039136e161a425c2ee1a3679da
https://doi.org/10.1124/dmd.107.015297

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Use of Fluorobenzoyl Protective Groups in Synthesis of Glycopeptides: β-Elimination ofO-Linked Carbohydrates Is Suppressed

Autor: Jan Kihlberg, Petter Sjölin

Publikováno v: The Journal of Organic Chemistry. 66:2957-2965

Fluorobenzoyl groups have been investigated as alternatives to acetyl and benzoyl protective groups in carbohydrate and glycopeptide synthesis. D-Glucose and lactose were protected with different fluorobenzoyl groups and then converted into glycosyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2672f470c98e56dacaf74d05ccbe69c
https://doi.org/10.1021/jo001584q

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Deacetylation of Nα-methylated glycopeptides reveals that aza-enolates provide protection against β-elimination of carbohydrates O-linked to serine

Autor: Petter Sjölin, Jan Kihlberg

Publikováno v: Tetrahedron Letters. 41:4435-4439

Three glycopeptides Ac-Ala-Ser[beta-Gal(OAc)(4)]-Phe-NH2, Ac-Ala-N-alpha-Me-Ser[beta-Gal(OAc)(4)]-Phe-NH2 and Ac-Ala-Ser[beta-Gal(OAc)(4)]-N-alpha-Me-Phe-NH2 have been prepared and treated with bas ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47c5a3ed2a68f75162182f0c8245057c
https://doi.org/10.1016/s0040-4039(00)00611-0

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Synthesis of deoxy and alanine-substituted derivatives of a T cell stimulating glycopeptide—An investigation of conditions for cleavage from the solid phase and deprotection

Autor: Jan Kihlberg, Anette Svensson, Sarbari Roy, Karl-Erik Bergquist, Petter Sjölin, Shaji K. George

Publikováno v: Journal of the Chemical Society, Perkin Transactions 1. :1731-1742

Little is known concerning how T cells recognize glycopeptides presented by MHC molecules on antigen-presenting cells. In order to probe the specificity of helper T cells elicited on immunization of mice with glycopeptide 1, which has the disaccharid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f90e64858e00acdd1623bca822c9743
https://doi.org/10.1039/a900435a

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Removal of Acyl Protective Groups from Glycopeptides: Base Does Not Epimerize Peptide Stereocenters, and β-Elimination Is Slow

Autor: Jan Kihlberg, Petter Sjölin, Mikael Elofsson

Publikováno v: The Journal of Organic Chemistry. 61:560-565

Epimerization of glycopeptide stereocenters and beta-elimination have been considered as important potential side reactions on deacylation of glycopeptides which have the carbohydrate moieties protected with O-acyl groups. Since no systematic investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa046321a45528d8e82fbf641bc0442
https://doi.org/10.1021/jo951817r

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Influence of saccharide size on the cellular immune response to glycopeptides

Autor: Thomas P. Cirrito, Mickael Mogemark, Petter Sjölin, Emil R. Unanue, Jan Kihlberg

Publikováno v: Organicbiomolecular chemistry. 1(12)

Glycopeptides that bind to MHC molecules on antigen presenting cells may elicit carbohydrate selective T cells. In order to investigate how the cellular immune response depends on the size of the carbohydrate moiety, a trigalactosylated derivative of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789f04d5d822e5a0d637b88f4e85833a
https://pubmed.ncbi.nlm.nih.gov/12945896

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