Zobrazeno 1 - 10
of 575
pro vyhledávání: '"Petrovas A"'
Autor:
Joana Dias, Giulia Fabozzi, Slim Fourati, Xuejun Chen, Cuiping Liu, David R. Ambrozak, Amy Ransier, Farida Laboune, Jianfei Hu, Wei Shi, Kylie March, Anna A. Maximova, Stephen D. Schmidt, Jakob Samsel, Chloe A. Talana, Keenan Ernste, Sung Hee Ko, Margaret E. Lucas, Pierce E. Radecki, Kristin L. Boswell, Yoshiaki Nishimura, John-Paul Todd, Malcolm A. Martin, Constantinos Petrovas, Eli A. Boritz, Nicole A. Doria-Rose, Daniel C. Douek, Rafick-Pierre Sékaly, Jeffrey D. Lifson, Mangaiarkarasi Asokan, Lucio Gama, John R. Mascola, Amarendra Pegu, Richard A. Koup
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Anti-HIV-1 broadly neutralizing antibodies (bNAbs) have the dual potential of mediating virus neutralization and antiviral effector functions through their Fab and Fc domains, respectively. So far, bNAbs with enhanced Fc effector functions i
Externí odkaz:
https://doaj.org/article/bf19edfc45874c86ab18e09d0df26155
Autor:
Mathilde Foglierini, Pauline Nortier, Rachel Schelling, Rahel R. Winiger, Philippe Jacquet, Sijy O’Dell, Davide Demurtas, Maxmillian Mpina, Omar Lweno, Yannick D. Muller, Constantinos Petrovas, Claudia Daubenberger, Matthieu Perreau, Nicole A. Doria-Rose, Raphael Gottardo, Laurent Perez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Broadly neutralizing antibodies (bNAbs) are promising candidates for the treatment and prevention of HIV-1 infections. Despite their critical importance, automatic detection of HIV-1 bNAbs from immune repertoires is still lacking. Here, we d
Externí odkaz:
https://doaj.org/article/9d102f79207c417eb04c2d3080c48cb2
Autor:
Chantziou, Amanda, Brenna, Cloe, Ioannidou, Kalliopi, Chen, Oliver Y., Korkolopoulou, Penelope, Antoniadou, Anastasia, Psichogiou, Mina, Papaioannou, Maria, Tsirigotis, Panagiotis, Foukas, Periklis G., de Leval, Laurence, Petrovas, Constantinos
Publikováno v:
In Blood Advances 24 December 2024 8(24):6215-6231
Autor:
Spiros Georgakis, Michail Orfanakis, Cloe Brenna, Simon Burgermeister, Perla M. Del Rio Estrada, Mauricio González-Navarro, Fernanda Torres-Ruiz, Gustavo Reyes-Terán, Santiago Avila-Rios, Yara Andrea Luna-Villalobos, Oliver Y. Chén, Giuseppe Pantaleo, Richard A. Koup, Constantinos Petrovas
Publikováno v:
Vaccines, Vol 12, Iss 8, p 912 (2024)
Follicular helper CD4hi T cells (TFH) are a major cellular pool for the maintenance of the HIV reservoir. Therefore, the delineation of the follicular (F)/germinal center (GC) immune landscape will significantly advance our understanding of HIV patho
Externí odkaz:
https://doaj.org/article/e34491b2bac84b12a559ae4ab2f0b6f8
Publikováno v:
Вісник аграрної науки Причорномор'я, Vol 27, Iss 3, Pp 31-45 (2023)
Long-term studies of tillage and crop management are essential in finding out which crop production practices would contribute to sustainable yields and profits. In the conditions of climate change, such issues as selection, forecasting and adjustmen
Externí odkaz:
https://doaj.org/article/f2f4effb54214fd884baba674bfd0211
Autor:
Wanwisa Promsote, Ling Xu, Jason Hataye, Giulia Fabozzi, Kylie March, Cassandra G. Almasri, Megan E. DeMouth, Sarah E. Lovelace, Chloe Adrienna Talana, Nicole A. Doria-Rose, Krisha McKee, Sabrina Helmold Hait, Joseph P. Casazza, David Ambrozak, Jochen Beninga, Ercole Rao, Norbert Furtmann, Joerg Birkenfeld, Elizabeth McCarthy, John-Paul Todd, Constantinos Petrovas, Mark Connors, Andrew T. Hebert, Jeremy Beck, Junqing Shen, Bailin Zhang, Mikhail Levit, Ronnie R. Wei, Zhi-yong Yang, Amarendra Pegu, John R. Mascola, Gary J. Nabel, Richard A. Koup
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Agents that can simultaneously activate latent HIV, increase immune activation and enhance the killing of latently-infected cells represent promising approaches for HIV cure. Here, we develop and evaluate a trispecific antibody (Ab), N6/αCD
Externí odkaz:
https://doaj.org/article/8e5eb98b4e8744a192139410ac1ac511
Autor:
Oyler, Benjamin L., Valencia-Dávila, Jeferson A., Moysi, Eirini, Molyvdas, Adam, Ioannidou, Kalliopi, March, Kylie, Ambrozak, David, De Leval, Laurence, Fabozzi, Giulia, Woods, Amina S., Koup, Richard A., Petrovas, Constantinos
Publikováno v:
In iScience 18 August 2023 26(8)
Akademický článek
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Akademický článek
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Autor:
Victor Joo, Constantinos Petrovas, Laurence de Leval, Alessandra Noto, Michel Obeid, Craig Fenwick, Giuseppe Pantaleo
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Therapeutic monoclonal antibodies (mAb) targeting the immune checkpoint inhibitor programmed cell death protein 1 (PD-1) have achieved considerable clinical success in anti-cancer therapy through relieving T cell exhaustion. Blockade of PD-1 interact
Externí odkaz:
https://doaj.org/article/065a7f9cf7cc45818a04a4f87b1fc2c0