Výsledky vyhledávání - "Petros Sotiriou"

3D Solution Structure of [Tyr3]Octreotate Derivatives in DMSO: Structure Differentiation of Peptide Core Due to Chelate Group Attachment and Biologically Active Conformation

Autor: Anastasia Nikolopoulou, Paul Cordopatis, Theodosia Maina, Petros Sotiriou, Athanassios S. Galanis, Berthold A. Nock, Christos Petrou, Georgios A. Spyroulias, D. Vahliotis

Publikováno v: Medicinal Chemistry. 1:487-499

The solution models of [Tyr3]octreotate (DPhe1-Cys2-Tyr3-DTrp4-Lys5-Thr6-Cys7-Thr8-COOH, disulfide bridged) (I), its analogs functionalized with an open chain tetraamine chelator, N4-[Tyr3]octreotate (II), and the N4-(Asp)2-[Tyr3]octreotate (III) pep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae763350143fbb980f2ceea99b2a2f4
https://doi.org/10.2174/1573406054864089

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[99mTc]Demotate, a new 99mTc-based [Tyr3]octreotate analogue for the detection of somatostatin receptor-positive tumours: synthesis and preclinical results

Autor: Paul Cordopatis, D Maintas, Anastasia Nikolopoulou, Theodosia Maina, Petros Sotiriou, Berthold A. Nock, Efstratios Chiotellis, George Loudos

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 29:742-753

Demotate is a new tetraamine-functionalised [Tyr3]octreotate derivative that binds technetium-99m with a high efficiency under mild conditions. The resulting radioligand, [99mTc]Demotate, forms in a high purity and is stable for at least 6 h after la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645a54da2edd3a06b6b7e56de1271c38
https://doi.org/10.1007/s00259-002-0782-9

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Tetraamine-modified octreotide and octreotate: labeling with 99mTc and preclinical comparison in AR4-2J cells and AR4-2J tumor-bearing mice

Autor: Anastasia Nikolopoulou, Petros Sotiriou, Theodosia Maina, Berthold A. Nock, Paul Cordopatis

Publikováno v: Journal of peptide science : an official publication of the European Peptide Society. 12(2)

Two somatostatin analogues, [(99m)Tc]Demotide and [(99m)Tc]Demotate 4, were compared with [(99m)Tc]Demotate 1, a previously reported somatostatin receptor subtype 2 (sst(2)) targeting tracer. Conjugates were prepared by coupling an open-chain tetraam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607d8c649c793c3baaf03fc3fd179143
https://pubmed.ncbi.nlm.nih.gov/16059963

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Technetium labeled tetramine-octreotate analogs efficiently localize in somatostatin binding sites in vivo

Autor: M. Poppe, Theodosia Maina, Paul Cordopatis, C. Tsipra, Petros Sotiriou, Berthold A. Nock, Vassiliki Magafa, A. Nicolopoulou, E. Chiotellis

Publikováno v: Nuclear Medicine Communications. 21:590

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7d967c3a54a6ee1557b2ba7db9d2593
https://doi.org/10.1097/00006231-200006000-00111

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Verknüpfung von Aminosäuren mit Hydroxygruppen enthaltenden Harzen und ihre Anwendung zur Synthese von Peptiden mitN-Tritylaminosäure-(1-benzotriazolylestern)

Autor: Wolfram Schäfer, Dionysios Papaioannou, Dimitrios Gatos, Kleomenis Barlos, John K. Kallitsis, Petros Sotiriou

Publikováno v: Liebigs Annalen der Chemie. 1987:1031-1035

Trt- und Fmoc-Aminosauren werden durch Triphenylphosphan (TPP) und Diethyl-azodicarboxylat (DEAD) mit p-Alkoxybenzylalkohol-Harz (ABAR, 1) und mit Diphenylmethanol-Harz (DPMR, 2) bei 0°C in Tetrahydrofuran verknupft. Die resultierenden Harze werden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73f7967efdd0f897a7e06651f169c969
https://doi.org/10.1002/jlac.198719870869

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Darstellung neuer säureempfindlicher Harze vom sek.-Alkohol-Typ und ihre Anwendung zur Synthese von Peptiden

Autor: Kleomenis Barlos, Dimitrios Gatos, Petros Sotiriou, Graham J. Moore, John Matsoukas, John Hondrelis, Wolfram Schäfer

Publikováno v: Liebigs Annalen der Chemie. 1989:951-955

Die substituierten Diphenylmethyl-Harze 5b–e und das α-Methylbenzyl-Harz 6 wurden hergestellt und nach der Methode von Mitsunobu mit Trt- und Fmoc-Aminosauren verestert. Nach wachsender Stabilitat ihrer Esterverknupfung mit Aminosauren gegenuber T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ce72994128781d2d49bd18793b9c608
https://doi.org/10.1002/jlac.198919890250

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Anwendung von 4-Polystyryltriphenylmethylchlorid zur Synthese von Peptiden und Aminosäure-Derivaten

Autor: Dionysios Papaioannou, Dimitrios Gatos, Petros Sotiriou, Ioannis Kallitsis, Kleomenis Barlos

Publikováno v: Liebigs Annalen der Chemie. 1988:1079-1081

Application of 4-Polystyryltriphenylmethyl Chloride to the Syntheses of Peptides and Amino Acid Derivatives Use of polymer-bound trityl chloride as an α-amino protecting group of amino acids allows simple and high-yield syntheses of amino acid deriv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b48ca353e9328538e3f27a24b2d9e7e
https://doi.org/10.1002/jlac.198819881110

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