Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Petrisor Alin Pirvan"'
Autor:
Laura Monaghan, Matthew E. Massett, Roderick P. Bunschoten, Alex Hoose, Petrisor-Alin Pirvan, Robert M. J. Liskamp, Heather G. Jørgensen, Xu Huang
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Growing evidence has demonstrated that epigenetic dysregulation is a common pathological feature in human cancer cells. Global alterations in the epigenetic landscape are prevalent in malignant cells across different solid tumors including, prostate
Externí odkaz:
https://doaj.org/article/ab95f53a65d24ebca606b6d13543a3fc
Autor:
Simon Rohrbach, Mindaugas Šiaučiulis, Greig Chisholm, Petrisor-Alin Pirvan, Michael Saleeb, S. Hessam M. Mehr, Ekaterina Trushina, Artem I. Leonov, Graham Keenan, Aamir Khan, Alexander Hammer, Leroy Cronin
Publikováno v:
Science (New York, N.Y.). 377(6602)
Despite huge potential, automation of synthetic chemistry has only made incremental progress over the past few decades. We present an automatically executable chemical reaction database of 100 molecules representative of the range of reactions found
Autor:
Joana Bittencourt-Silvestre, Petrisor Alin Pirvan, Roderick P. Bunschoten, Rob M. J. Liskamp, Taeju Park, Xu Huang, Heather G. Jørgensen, Matthew E. Massett, Laura Monaghan, Alex Hoose
Publikováno v:
Blood. 134:3756-3756
Epigenetic therapies are emerging as a promising therapeutic strategy for acute myeloid leukemia (AML), exemplified by advances in the development of inhibitors targeting DNMT3A, DOT1L and LSD1. We identified an essential role for the H3K9me3 histone