Výsledky vyhledávání - "Petri Hyytiä"

Akademický článek

Alcohol Co-Administration Changes Mephedrone-Induced Alterations of Neuronal Activity

Autor: Milo Grotell, Bjørnar den Hollander, Aaro Jalkanen, Essi Törrönen, Jouni Ihalainen, Elena de Miguel, Mateusz Dudek, Mikko I. Kettunen, Petri Hyytiä, Markus M. Forsberg, Esko Kankuri, Esa R. Korpi

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Mephedrone (4-MMC), despite its illegal status, is still a widely used psychoactive substance. Its effects closely mimic those of the classical stimulant drug methamphetamine (METH). Recent research suggests that unlike METH, 4-MMC is not neurotoxic

Externí odkaz: https://doaj.org/article/a8c218f928c34b7cad371de400fd6571

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Akademický článek

Acute Lysergic Acid Diethylamide Does Not Influence Reward-Driven Decision Making of C57BL/6 Mice in the Iowa Gambling Task

Autor: Lauri V. Elsilä, Nuppu Korhonen, Petri Hyytiä, Esa R. Korpi

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

While interest in psychedelic drugs in the fields of psychiatry and neuroscience has re-emerged in recent last decades, the general understanding of the effects of these drugs remains deficient. In particular, there are gaps in knowledge on executive

Externí odkaz: https://doaj.org/article/17ec6fd46ebe47eab8b598c68f163757

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Akademický článek

Chemogenetic Stimulation and Silencing of the Insula, Amygdala, Nucleus Accumbens, and Their Connections Differentially Modulate Alcohol Drinking in Rats

Autor: Mia Haaranen, Annika Schäfer, Vilja Järvi, Petri Hyytiä

Publikováno v: Frontiers in Behavioral Neuroscience, Vol 14 (2020)

The anterior insular cortex is hypothesized to represent interoceptive effects of drug reward in the service of goal-directed behavior. The insula is richly connected, but the insula circuitry in addiction remains poorly characterized. We examined th

Externí odkaz: https://doaj.org/article/9123f834d46c494b8bfb87929e318839

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Node of Ranvier remodeling in chronic psychosocial stress and anxiety

Autor: Maija-Kreetta Koskinen, Mikaela Laine, Ali Abdollahzadeh, Adrien Gigliotta, Giulia Mazzini, Sarah Journée, Varpu Alenius, Kalevi Trontti, Jussi Tohka, Petri Hyytiä, Alejandra Sierra, Iiris Hovatta

Publikováno v: Neuropsychopharmacology.

Differential expression of myelin-related genes and changes in myelin thickness have been demonstrated in mice after chronic psychosocial stress, a risk factor for anxiety disorders. To determine whether and how stress affects structural remodeling o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::788efee646b65ba66fefd44d6bfcc541
https://doi.org/10.1038/s41386-023-01568-6

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Brain Network Allostasis after Chronic Alcohol Drinking Is Characterized by Functional Dedifferentiation and Narrowing

Autor: Úrsula Pérez-Ramírez, Víctor J. López-Madrona, Andrés Pérez-Segura, Vicente Pallarés, Andrea Moreno, Roberto Ciccocioppo, Petri Hyytiä, Wolfgang H. Sommer, David Moratal, Santiago Canals

Publikováno v: J Neurosci

Alcohol use disorder (AUD) causes complex alterations in the brain that are poorly understood. The heterogeneity of drinking patterns and the high incidence of comorbid factors compromise mechanistic investigations in AUD patients. Here we used male

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30c47e4d6c958f224807959dfa2a249
http://hdl.handle.net/10138/351154

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Voluntary Adolescent-Onset Alcohol Drinking Fails to Influence Alcohol Consumption or Anxiety-Like Behaviour in Adulthood in Female Alcohol-Preferring Rats

Autor: Ekaterina Mugantseva, Antti Latvala, Petri Hyytiä

Aims Alcohol exposure during adolescence is associated with both increased risk for alcohol use disorders and anxiety in adulthood. Our present experiments examined this association using alcohol-preferring AA (Alko Alcohol) rats selected for high vo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f5fdc6ca095ebd5b4fac0d133714c0
http://hdl.handle.net/10138/346631

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The bradykinin system in stress and anxiety in humans and mice

Autor: William McEntegart, Ari Rouhiainen, Kalevi Trontti, Petri Hyytiä, Iiris Hovatta, Marie Mennesson, Suvi Saarnio, Tessa Sipilä, Lea Martta Urpa, Zuzanna Misiewicz, Natalia Kulesskaya, Ewa Sokolowska

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports

Pharmacological research in mice and human genetic analyses suggest that the kallikrein-kinin system (KKS) may regulate anxiety. We examined the role of the KKS in anxiety and stress in both species. In human genetic association analysis, variants in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e713fad50a724055f1743e404234ecdb
http://link.springer.com/article/10.1038/s41598-019-55947-5

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Neuroimaging reveals functionally distinct neuronal networks associated with high-level alcohol consumption in two genetic rat models

Autor: Vicente Pallarés, David Moratal, Mateusz Dudek, Mia Haaranen, Andrea Moreno, Wolfgang H. Sommer, Santiago Canals, Úrsula Pérez-Ramírez, Roberto Ciccocioppo, Petri Hyytiä

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Behavioral Pharmacology
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia

Human imaging data suggest that the motivational processes associated with alcohol reward are reflected in the patterns of neural activation after alcohol or alcohol-related cues. In animal models of alcohol drinking, however, the changes in brain ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278c6132242b51f76bbc3c456cc7d475
http://hdl.handle.net/10261/231151

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Acute Lysergic Acid Diethylamide Does Not Influence Reward-Driven Decision Making of C57BL/6 Mice in the Iowa Gambling Task

Autor: Petri Hyytiä, Lauri Elsilä, Esa R. Korpi, Nuppu Korhonen

Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061f8d1e548bb31629a0aeacfc033d03
http://europepmc.org/articles/PMC7745734

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Anterior insula stimulation suppresses appetitive behavior while inducing forebrain activation in alcohol-preferring rats

Autor: Angelo Bifone, Stefano Tambalo, Petri Hyytiä, Sine Mandrup Bertozzi, Mia Haaranen, Wolfgang H. Sommer, Giulia Scuppa, Andrea Armirotti, Vilja Järvi

Publikováno v: Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Translational Psychiatry

The anterior insular cortex plays a key role in the representation of interoceptive effects of drug and natural rewards and their integration with attention, executive function, and emotions, making it a potential target region for intervention to co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afb72cc58dbe7fa2052027deec403c9
http://hdl.handle.net/10138/316286

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