Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Petri, Kursula"'
Autor:
Olav Tenstad, Eleni Christakou, Linn Hodneland Nilsson, Gro Gausdal, David Micklem, Petri Kursula, James B. Lorens, Rolf K. Reed
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Soluble biomarkers are paramount to personalized medicine. However, the in vivo turnover and biodistribution of soluble proteins is seldom characterized. The cleaved extracellular domain of the AXL receptor (sAXL) is a prognostic biomarker i
Externí odkaz:
https://doaj.org/article/7cd00871860a442ab5032350c2e15f75
Autor:
José M Godoy Muñoz, Lasse Neset, Sigurbjörn Markússon, Sarah Weber, Oda C Krokengen, Aleksi Sutinen, Eleni Christakou, Andrea J Lopez, Clive R Bramham, Petri Kursula
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0300453 (2024)
The activity-regulated cytoskeleton-associated protein (Arc) is a complex regulator of synaptic plasticity in glutamatergic neurons. Understanding its molecular function is key to elucidate the neurobiology of memory and learning, stress regulation,
Externí odkaz:
https://doaj.org/article/d6ab482ccff94e108f2968ea805e64c2
Autor:
Laura Kind, Mark Driver, Arne Raasakka, Patrick R. Onck, Pål Rasmus Njølstad, Thomas Arnesen, Petri Kursula
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Hepatocyte nuclear factor 1α (HNF-1A) is a transcription factor with important gene regulatory roles in pancreatic β-cells. HNF1A gene variants are associated with a monogenic form of diabetes (HNF1A-MODY) or an increased risk for type 2 diabetes.
Externí odkaz:
https://doaj.org/article/6d60e27d16fb4b7b8a3edf13ada0e079
Publikováno v:
Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101474- (2023)
Numerous human proteins are classified as intrinsically disordered proteins (IDPs). Due to their physicochemical properties, high-resolution structural information about IDPs is generally lacking. On the other hand, IDPs are known to adopt local orde
Externí odkaz:
https://doaj.org/article/8a58a62a3fb2455fae8305dae6317e97
Autor:
Aleksi Sutinen, Giang Thi Tuyet Nguyen, Arne Raasakka, Gopinath Muruganandam, Remy Loris, Emil Ylikallio, Henna Tyynismaa, Luca Bartesaghi, Salla Ruskamo, Petri Kursula
Publikováno v:
FEBS Open Bio, Vol 12, Iss 7, Pp 1306-1324 (2022)
Charcot–Marie–Tooth disease (CMT) is the most common inherited peripheral polyneuropathy in humans, and its different subtypes are linked to mutations in dozens of different genes. Mutations in ganglioside‐induced differentiation‐associated p
Externí odkaz:
https://doaj.org/article/4e1bc0752cf64ca19c72433a691f3831
Autor:
Aleksi Sutinen, Dirk Paffenholz, Giang Thi Tuyet Nguyen, Salla Ruskamo, Andrew E Torda, Petri Kursula
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284532 (2023)
Charcot-Marie-Tooth disease (CMT) is the most common inherited peripheral polyneuropathy in humans, and its subtypes are linked to mutations in dozens of different genes, including the gene coding for ganglioside-induced differentiation-associated pr
Externí odkaz:
https://doaj.org/article/e83e38a300f440f6879281dd0fbdaa4a
Autor:
Mirella Vinci, Petri Kursula, Donatella Greco, Maurizio Elia, Luigi Vetri, Carmelo Schepis, Valeria Chiavetta, Serena Donadio, Michele Roccella, Marco Carotenuto, Valentino Romano, Francesco Calì
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 9, Pp n/a-n/a (2022)
Abstract Background The AHNAK2 gene encodes a large nucleoprotein expressed in several tissues, including brain, squamous epithelia, smooth muscle, and neuropil. Its role in calcium signaling has been suggested and to date, clear evidence about its i
Externí odkaz:
https://doaj.org/article/c863386b717d400bb0253b535cdc532e
Autor:
Giang Thi Tuyet Nguyen, Aleksi Sutinen, Arne Raasakka, Gopinath Muruganandam, Remy Loris, Petri Kursula
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/8ee59593876341d385aa534f83091d59
Autor:
Sigurbjörn Markússon, Erik I. Hallin, Helene J. Bustad, Arne Raasakka, Ju Xu, Gopinath Muruganandam, Remy Loris, Aurora Martinez, Clive R. Bramham, Petri Kursula
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Activity-regulated cytoskeleton-associated protein (Arc) is a multidomain protein of retroviral origin with a vital role in the regulation of synaptic plasticity and memory formation in mammals. However, the mechanistic and structural basis of Arc fu
Externí odkaz:
https://doaj.org/article/92f7c7178b3445c785ad94231b2c6722
Autor:
Dana Bohan, Hanora Van Ert, Natalie Ruggio, Kai J Rogers, Mohammad Badreddine, José A Aguilar Briseño, Jonah M Elliff, Roberth Anthony Rojas Chavez, Boning Gao, Tomasz Stokowy, Eleni Christakou, Petri Kursula, David Micklem, Gro Gausdal, Hillel Haim, John Minna, James B Lorens, Wendy Maury
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009743 (2021)
Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through virion-associated PS binding that is termed apoptotic mimicry. Here we show that this broadly shared uptake mechanism is utilized by SARS-CoV-2 in cells that expres
Externí odkaz:
https://doaj.org/article/263446c892cf4c9fa83fd3b8a0e7c84e