Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Petra Willems"'
Autor:
Petra Willems, Zhanat Carr, Steffen Dreger, Hajo Zeeb, Nathalie Tchilian-Teng, Veronica Smith, Lodewijk Van Bladel
Publikováno v:
Environmental Advances, Vol 8, Iss , Pp 100252- (2022)
Severe nuclear accidents may lead to a release of radioactivity, including radioactive iodine, into the environment. The thyroid gland in the human body needs natural or stable iodine to function properly and this iodine is normally absorbed in small
Externí odkaz:
https://doaj.org/article/2f5dbc66469f455186894fad39efdcd3
Autor:
Petra Willems, Zhanat Carr, Steffen Dreger, Hajo Zeeb, Nathalie Tchilian-Teng, Veronica Smith, Lodewijk Van Bladel
Publikováno v:
Environmental advances, 8:100252
Severe nuclear accidents may lead to a release of radioactivity, including radioactive iodine, into the environment. The thyroid gland in the human body needs natural or stable iodine to function properly and this iodine is normally absorbed in small
Autor:
Katrien Mortelmans, Pascal Fias, Petra Willems, Pieter Oosthoek, Ulrik Van Soom, Karolien van Nunen, Virginie de Gelder, Hubert Thierens
Publikováno v:
Tijdschrift voor bedrijfs-en verzekeringsgeneeskunde
In deze casus wordt een stralingsongeval besproken dat plaatsvond in België in 2012. Tijdens het incident liep een stralingsmedewerker een onwaarschijnlijk hoge dosis straling op. Doordat de stralingsmedewerker onvoldoende op de hoogte was van de mo
Publikováno v:
Cancer Genetics and Cytogenetics. 163:106-112
Recently, multiple studies have shown that a sequence variant in CHEK2 (CHEK2 1100delC) plays a role in the susceptibility to breast cancer. This mutation should confer about a twofold increased breast cancer risk in women and a 10-fold increased ris
Autor:
Ans Baeyens, Kathleen Claes, Bruce Poppe, Hubert Thierens, Gianpaolo Perletti, Petra Willems, Anne Vral
Publikováno v:
Molecular Medicine Reports.
Enhanced in vitro chromosomal radiosensitivity (CRS) has been proposed as a marker for low-penetrance gene mutations predisposing to breast cancer (BC). Since the double strand break (DSB) is the most detrimental form of DNA damage induced by ionizin
Autor:
Gianpoalo Perletti, Anne Vral, Jacobus Slabbert, Emanuela Marras, Hubert Thierens, Monica Mancini, Petra Willems, Jan Philippé, Veerle Vandersickel, Ellen Deschepper
Publikováno v:
International journal of radiation biology. 86(2)
To investigate the radiosensitising effect of Ku autoantigen 70 (Ku70) and Ku autoantigen 80 (Ku80) knockdown by lentivirus-mediated RNA interference (RNAi) in the MCF10A immortalised human mammary epithelial cell line.MCF10A cells were infected with
Autor:
Ursula Oestreicher, Anne Vral, Jacobus Slabbert, Hubert Thierens, Petra Willems, Liezel August, Horst Romm
Publikováno v:
International Journal of Radiation Biology
In case of a large-scale radiation accident when hundreds of people may be exposed, it is important to distinguish the severely exposed individuals (or =1 gray), who require early medical treatment, from those less exposed. The aim of our study was t
Autor:
Maja Čretnik, Gianpaolo Perletti, A Jakubowska, Vittorio Magri, Hubert Thierens, Vesna Musani, Anne Vral, Mauro Fasano, Veerle Vandersickel, Sonja Levanat, Emanuela Marras, Petra Willems, Jan Lubinski
Publikováno v:
International Journal of Oncology
In the Milan area (Northern Italy), we identified a family characterized by a high prevalence of ovarian and breast cancer cases (5 out of 6 subjects, over 3 generations), and a predominant prevalence of ovarian lesions (4 out of 5 patients). Analysi
Autor:
Petra Willems, Kim De Ruyck, Rudy Van den Broecke, Hubert Thierens, Anne Vral, Amin Makar, Gianpaolo Perletti
Publikováno v:
Journal of cancer research and clinical oncology. 135(9)
Polymorphisms in double strand break repair genes could be involved in genetic breast cancer predisposition as enhanced chromosomal radiosensitivity is a hallmark for breast cancer. Previously, the c.-1310 C>G SNP, located in the Ku70 promoter, showe
Autor:
Liv Veldeman, Joke Werbrouck, Hubert Thierens, Kim De Ruyck, Wilfried De Neve, Kathleen Claes, Tom Boterberg, Anne Vral, Petra Willems, Fréderic Duprez, Marc Van Eijkeren
Publikováno v:
International journal of radiation oncology, biology, physics. 73(4)
Purpose To investigate the association between dose-related parameters and polymorphisms in DNA DSB repair genes XRCC3 ( c.-1843A>G, c.562–14A>G, c.722C>T), Rad51 (c.-3429G>C, c.-3392G>T), Lig4 (c.26C>T, c.1704T>C), Ku70 (c.-1310C>G), and Ku80 (c.2