Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Petra Weinmann"'
Autor:
AKM Haque, Petra Weinmann, Sumit Biswas, Rupert Handgretinger, Markus Mezger, Michael Kormann, Justin Antony
Publikováno v:
Bio-Protocol, Vol 10, Iss 24 (2020)
The mRNA therapeutics is a new class of medicine to treat many various diseases. However, in vitro transcribed (IVT) mRNA triggers immune responses due to recognition by human endosomal and cytoplasmic RNA sensors, but incorporation of modified nucle
Externí odkaz:
https://doaj.org/article/c810918493a84bb4aafe5efc21f13e16
Publikováno v:
Molecular Therapy
Protein supplementation therapy using in vitro-transcribed (IVT) mRNA for genetic diseases contains huge potential as a new class of therapy. From the early ages of synthetic mRNA discovery, a great number of studies showed the versatile use of IVT m
Autor:
Brian Weidensee, Georg R Schweizer, Petra Weinmann, Michael S. D. Kormann, Itishri Sahu, Tatjana Michel, Hans Peter Wendel, Brigitta Loretz, Claus-Michael Lehr, A. K. M. Ashiqul Haque
Publikováno v:
COPD: Journal of Chronic Obstructive Pulmonary Disease. 16:209-210
Gene deficiency diseases where there is lack of functional protein, have found a potential cure in the form of mRNA therapy (1) but major challenges for achieving higher bioavailability concerning ...
Autor:
Justin S, Antony, Ngadhnjim, Latifi, A K M Ashiqul, Haque, Andrés, Lamsfus-Calle, Alberto, Daniel-Moreno, Sebastian, Graeter, Praveen, Baskaran, Petra, Weinmann, Markus, Mezger, Rupert, Handgretinger, Michael S D, Kormann
Publikováno v:
Molecular and Cellular Pediatrics
Background β-Thalassemia is an inherited hematological disorder caused by mutations in the human hemoglobin beta (HBB) gene that reduce or abrogate β-globin expression. Although lentiviral-mediated expression of β-globin and autologous transplanta
Autor:
Petra Weinmann, Praveen Baskaran, Alberto Daniel-Moreno, Justin S. Antony, Sebastian Graeter, Michael S. D. Kormann, Markus Mezger, Rupert Handgretinger, Ngadhnjim Latifi, Andrés Lamsfus-Calle, A. K. M. Ashiqul Haque
Publikováno v:
Molecular and Cellular Pediatrics
β-Thalassemia is an inherited hematological disorder caused by mutations in the human hemoglobin beta (HBB) gene that reduce or abrogate β-globin expression. Although lentiviral-mediated expression of β-globin and autologous transplantation is a p
Autor:
Rupert Handgretinger, Justin S. Antony, Michael S. D. Kormann, Markus Mezger, Sumit Biswas, Akm Ashiqul Haque, Petra Weinmann
Publikováno v:
ADVANCES IN CELL AND GENE THERAPY
Autor:
A. K. M. Ashiqul Haque, Julie Laval, Brigitta Loretz, Ngadhnjim Latifi, Claus-Michael Lehr, Christian Seitz, Elvira Sondo, Patrick Schlegel, Hanzey Yasar, Anjali Ralhan, Alexander Dewerth, Rupert Handgretinger, Petra Weinmann, Justin S. Antony, Nicoletta Pedemonte, Brian Weidensee, Joachim Riethmüller, Michael S. D. Kormann, Georg R Schweizer
Publikováno v:
Scientific Reports
Scientific reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Gene therapy has always been a promising therapeutic approach for Cystic Fibrosis (CF). However, numerous trials using DNA or viral vectors encoding the correct protein resulted in a general low efficacy. In the last years, chemically modified messen