Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Petra Wahle"'
Autor:
Steffen Gonda, Ina Köhler, André Haase, Katrin Czubay, Andrea Räk, Christian Riedel, Petra Wahle
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Spontaneous or experimentally evoked activity can lead to changes in length and/or branching of neocortical pyramidal cell dendrites. For instance, an early postnatal overexpression of certain AMPA or kainate glutamate receptor subunits leads to larg
Externí odkaz:
https://doaj.org/article/7bf503b331d64f079eaead16fe19e3aa
Autor:
Ina Gasterstädt, Max Schröder, Lukas Cronin, Julian Kusch, Lisa-Marie Rennau, Brix Mücher, Stefan Herlitze, Alexander Jack, Petra Wahle
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Electrical activity is considered a key driver for the neurochemical and morphological maturation of neurons and the formation of neuronal networks. Designer receptors exclusively activated by designer drugs (DREADDs) are tools for controlling neuron
Externí odkaz:
https://doaj.org/article/3079662117524590922aae64e85c838f
Autor:
Petra Wahle, Eric Sobierajski, Ina Gasterstädt, Nadja Lehmann, Susanna Weber, Joachim HR Lübke, Maren Engelhardt, Claudia Distler, Gundela Meyer
Publikováno v:
eLife, Vol 11 (2022)
The canonical view of neuronal function is that inputs are received by dendrites and somata, become integrated in the somatodendritic compartment and upon reaching a sufficient threshold, generate axonal output with axons emerging from the cell body.
Externí odkaz:
https://doaj.org/article/7875a5d0ad9743bfa4a15d4216a7ad56
Autor:
Steffen Gonda, Jan Giesen, Alexander Sieberath, Fabian West, Raoul Buchholz, Oliver Klatt, Tim Ziebarth, Andrea Räk, Sabine Kleinhubbert, Christian Riedel, Michael Hollmann, Mohammad I. K. Hamad, Andreas Reiner, Petra Wahle
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
NMDA receptors are important players for neuronal differentiation. We previously reported that antagonizing NMDA receptors with APV blocked the growth-promoting effects evoked by the overexpression of specific calcium-permeable or flip-spliced AMPA r
Externí odkaz:
https://doaj.org/article/78db26972dbd41cda94424c8ff27acb1
Autor:
Ina Gasterstädt, Alexander Jack, Tobias Stahlhut, Lisa-Marie Rennau, Steffen Gonda, Petra Wahle
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
A battery of genetically encoded calcium indicators (GECIs) with different binding kinetics and calcium affinities was developed over the recent years to permit long-term calcium imaging. GECIs are calcium buffers and therefore, expression of GECIs m
Externí odkaz:
https://doaj.org/article/7f99187b9dd346ed80f0ef6fedd4bf4c
Autor:
Janine R Neumann, Suvarna Dash-Wagh, Alexander Jack, Andrea Räk, Kay Jüngling, Mohammad I K Hamad, Hans-Christian Pape, Michael R Kreutz, Martin Puskarjov, Petra Wahle
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211151 (2019)
The 30-amino acid peptide Y-P30 corresponds to the N-terminus of the primate-specific, sweat gland-derived dermcidin prepropeptide. Previous work has revealed that Y-P30 enhances the interaction of pleiotrophin and syndecans-2/3, and thus represents
Externí odkaz:
https://doaj.org/article/5c2988e9542a4f6f8a161ca1f6c5a2f6
Autor:
Felix Höfflin, Alexander Jack, Christian Riedel, Julia Mack-Bucher, Johannes Roos, Corinna Corcelli, Christian Schultz, Petra Wahle, Maren Engelhardt
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The microdomain that orchestrates action potential initiation in neurons is the axon initial segment (AIS). It has long been considered to be a rather homogeneous domain at the very proximal axon hillock with relatively stable length, particularly in
Externí odkaz:
https://doaj.org/article/d530c007fe0f444eb8df5bc797e7c9bb
Autor:
Peter Landgraf, Marina Mikhaylova, Tamar Macharadze, Corinna Borutzki, Ana-Claudia Zenclussen, Petra Wahle, Michael R Kreutz
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e85924 (2014)
The survival promoting peptide Y-P30 has documented neuroprotective effects as well as cell survival and neurite outgrowth promoting activity in vitro and in vivo. Previous work has shown that multimerization of the peptide with pleiotrophin (PTN) an
Externí odkaz:
https://doaj.org/article/e1be726a58ac4b76b65bad4c45ecf3c1
Autor:
Pauline Lafenetre, Oliver Leske, Zhanlu Ma-Högemeie, Aiden Haghikia, Zoe Bichler, Petra Wahle, Rolf Heumann
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 3 (2010)
Running is a potent stimulator of cell proliferation in the adult dentate gyrus and these newly generated hippocampal neurons seem to be implicated in memory functions. Here we have used a mouse model expressing activated Ras under the direction of t
Externí odkaz:
https://doaj.org/article/b078374559ed4272b243cfb52e1484c3
Development of myelin in fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa
Autor:
Eric Sobierajski, German Lauer, Katrin Czubay, Hannah Grabietz, Christa Beemelmans, Christoph Beemelmans, Gundela Meyer, Petra Wahle
Publikováno v:
Brain Structure and Function. 228:947-966
Myelination of the neocortex of altricial species is mostly a postnatal event, and the appearance of myelin has been associated with the end of the critical period for ocular dominance plasticity in rodent visual cortex. Due to their precocality, ung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe2ce610462a751956c67b9caaa7dac0
https://doi.org/10.1007/s00429-023-02633-y
https://doi.org/10.1007/s00429-023-02633-y