Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Petra Vrabcova"'
Autor:
Adam Klocperk, Jana Vcelakova, Petra Vrabcova, Irena Zentsova, Lenka Petruzelkova, Zdenek Sumnik, Stepanka Pruhova, Anna Sediva, Zuzana Parackova
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Type 1 diabetes (T1D) is an autoimmune disorder with unambiguous involvement of both innate and adaptive immune mechanisms in the destruction of pancreatic beta cells. Recent evidence demonstrated that neutrophils infiltrate the pancreas prior to dis
Externí odkaz:
https://doaj.org/article/a169e107ee2647559c422730bc83fbee
Autor:
Zuzana Parackova, Irena Zentsova, Petra Vrabcova, Adam Klocperk, Zdenek Sumnik, Stepanka Pruhova, Lenka Petruzelkova, Robert Hasler, Anna Sediva
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neutrophils releasing neutrophil extracellular traps (NETs) infiltrate the pancreas prior to type 1 diabetes (T1D) onset; however, the precise nature of their contribution to disease remains poorly defined. To examine how NETs affect immune functions
Externí odkaz:
https://doaj.org/article/5333061925c045c182ea366222199c06
Autor:
Irena Zentsova, Zuzana Parackova, Jana Kayserova, Lenka Palova-Jelinkova, Petra Vrabcova, Nikol Volfova, Zdenek Sumnik, Stepanka Pruhova, Lenka Petruzelkova, Anna Sediva
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
Inflammasomes are large protein complexes involved in the maturation of IL-1β, a cytokine associated with the pathophysiology of type 1 diabetes (T1D). The data presented in this article focused on the role of inflammasomes in DNA recognition in T1D
Externí odkaz:
https://doaj.org/article/4b11c74f4b424bceb39ab1d851585156
Autor:
Zuzana Parackova, Irena Zentsova, Marketa Bloomfield, Petra Vrabcova, Jitka Smetanova, Adam Klocperk, Grigorij Mesežnikov, Luis Fernando Casas Mendez, Tomas Vymazal, Anna Sediva
Publikováno v:
Cells, Vol 9, Iss 10, p 2206 (2020)
COVID-19, caused by SARS-CoV-2 virus, emerged as a pandemic disease posing a severe threat to global health. To date, sporadic studies have demonstrated that innate immune mechanisms, specifically neutrophilia, NETosis, and neutrophil-associated cyto
Externí odkaz:
https://doaj.org/article/d55db0ead0674da38051e88db0faa477
Publikováno v:
Clinical immunology (Orlando, Fla.). 246
STAT1 gain-of-function (GOF) mutations underlie an inborn error of immunity hallmarked by chronic mucocutaneous candidiasis (CMC). Beyond the fungal susceptibility, attributed to Th17 failure, over half of the reported patients suffer from autoimmune
Signal transducer and activator of transcription 1 (STAT1) gain-of-function (GOF) mutations underlie an inborn error of immunity called chronic mucocutaneous candidiasis. Beyond the fungal susceptibility, attributed to Th17 failure, over half of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267c221ae99c4f355dad80d77e2e0568
https://doi.org/10.22541/au.165629547.71126020/v1
https://doi.org/10.22541/au.165629547.71126020/v1
Publikováno v:
Clinical Immunology. 250:109384
Autor:
Anna Sediva, Adam Klocperk, Irena Zentsova, Zuzana Parackova, Jana Vcelakova, Zdenek Sumnik, Petra Vrabcova, Stepanka Pruhova, Lenka Petruzelkova
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Type 1 diabetes (T1D) is an autoimmune disorder with unambiguous involvement of both innate and adaptive immune mechanisms in the destruction of pancreatic beta cells. Recent evidence demonstrated that neutrophils infiltrate the pancreas prior to dis
Autor:
Jean-Laurent Casanova, Tomas Milota, Zuzana Parackova, Eva Fronkova, Marketa Bloomfield, Michael Svaton, Anna Sediva, Jacinta Bustamante, Irena Zentsova, Adam Klocperk, Petra Vrabcova
Publikováno v:
Journal of Clinical Immunology. 40:165-178
Blau syndrome (BS) is an auto-inflammatory granulomatous disease that possibly involves abnormal response to interferon gamma (IFNγ) due to exaggerated nucleotide-binding oligomerization domain containing 2 (NOD2) activity. Mendelian susceptibility
Autor:
Tomas Vymazal, Josef Zamecnik, Zuzana Parackova, Martin Tulach, Adam Klocperk, Marketa Bloomfield, Anna Sediva, Luis Fernando Casas Mendez, Irena Zentsova, Petra Vrabcova, Grigorij Meseznikov, Jan Balko, Jan Sipek, Alzbeta Grandcourtova
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 3000, p 3000 (2020)
Journal of Clinical Medicine
Volume 9
Issue 9
Journal of Clinical Medicine
Volume 9
Issue 9
This study aimed to assess the key laboratory features displayed by coronavirus disease 2019 (COVID-19) inpatients that are associated with mild, moderate, severe, and fatal courses of the disease, and through a longitudinal follow-up, to understand