Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Petra Vlckova"'
Autor:
Sami Znati, Rebecca Carter, Marcos Vasquez, Adam Westhorpe, Hassan Shahbakhti, Jessica Prince, Petra Vlckova, Chiara De Vellis, Zainab Bascal, Marilena Loizidou, Ricky A. Sharma
Publikováno v:
Cancers, Vol 12, Iss 7, p 1878 (2020)
Hepatocellular Carcinoma (HCC) is increasing in incidence worldwide and requires new approaches to therapy. The combination of anti-angiogenic drug therapy and radiotherapy is one promising new approach. The anti-angiogenic drug vandetanib is a tyros
Externí odkaz:
https://doaj.org/article/90baf685f95b4919850002374b9cd6d9
Autor:
Jahangir Sufi, Jeroen Claus, Petra Vlckova, Christopher Tape, Xiao Qin, Ferran Cardoso Rodriguez
Cancer cells are regulated by oncogenic mutations and microenvironmental signals, yet these processes are often studied separately. To functionally map how cell-intrinsic and cell-extrinsic cues co-regulate cell-fate in colorectal cancer (CRC), we pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5ce9cbb4a84d64590146c3eca249dfb
https://doi.org/10.1101/2023.02.15.528008
https://doi.org/10.1101/2023.02.15.528008
Autor:
Smita Krishnaswamy, Jahangir Sufi, Alexander Tong, Daniel Hochhauser, Petra Vlckova, Callum Baird Nattress, Christopher Tape, Maria Ramos Zapatero, Xiao Qin, Ferran Cardoso Rodriguez
Patient-derived organoids (PDOs) can model personalized therapy responses, however current screening technologies cannot reveal drug response mechanisms or study how tumor microenvironment cells alter therapeutic performance. To address this, we deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87d11527e867065290abc848d874747b
https://doi.org/10.1101/2022.10.19.512668
https://doi.org/10.1101/2022.10.19.512668
Autor:
Mark Nitz, Petra Vlckova, Jahangir Sufi, Christopher J. Tape, Xiao Qin, Yong Jia Bu, Ferran Cardoso Rodriguez, María Ramos Zapatero
Publikováno v:
Nature Protocols. 16:4897-4918
Organoids are biomimetic tissue models comprising multiple cell types and cell states. Post-translational modification (PTM) signaling networks control cellular phenotypes and are frequently dysregulated in diseases such as cancer. Although signaling
Autor:
Pelagia Kyriakidou, Xiao Qin, Sophie E. Acton, Mark Nitz, Petra Vlckova, Vivian S. W. Li, Christopher J. Tape, Jahangir Sufi
Organoids are powerful biomimetic tissue models. Despite their increasing popularity, no existing methods are suitable for cell-type specific analysis of post-translational modification (PTM) signalling networks in organoids. Here we report a multiva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c32517f023beeecf278cb8d924d2356
https://doi.org/10.21203/rs.2.16232/v2
https://doi.org/10.21203/rs.2.16232/v2
Autor:
Vivian S. W. Li, Sophie E. Acton, Xiao Qin, Mark Nitz, Jahangir Sufi, Christopher J. Tape, Petra Vlckova, Pelagia Kyriakidou
Publikováno v:
Nature methods
Organoids are powerful biomimetic tissue models. Despite their widespread adoption, methods to analyse cell-type specific post-translational modification (PTM) signalling networks in organoids are absent. Here we report multivariate single-cell analy
Autor:
Vivian S. W. Li, Xiao Qin, Jahangir Sufi, Pelagia Kyriakidou, Mark Nitz, Petra Vlckova, Sophie E. Acton, Christopher J. Tape
Organoids are powerful biomimetic tissue models. Despite their widespread adoption, methods to analyse cell-type specific post-translational modification (PTM) signalling networks in organoids are absent. Here we report multivariate single-cell analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644e41dd47dbc65895ba5852f18908a0
Autor:
Z. A. Bascal, Hassan Shahbakhti, Sami A. Znati, Adam Westhorpe, Jessica Prince, Petra Vlckova, Marcos Duran Vasquez, Chiara De Vellis, Marilena Loizidou, Rebecca Carter, Ricky A. Sharma
Publikováno v:
Cancers
Volume 12
Issue 7
Cancers, Vol 12, Iss 1878, p 1878 (2020)
Volume 12
Issue 7
Cancers, Vol 12, Iss 1878, p 1878 (2020)
Hepatocellular Carcinoma (HCC) is increasing in incidence worldwide and requires new approaches to therapy. The combination of anti-angiogenic drug therapy and radiotherapy is one promising new approach. The anti-angiogenic drug vandetanib is a tyros
Autor:
Anna Jonasova, Krivjanska M, Marek Trneny, Monika Belickova, Emanuel Necas, Karina Vargova, Filipp Savvulidi, Nikola Curik, Hana Hájková, Petra Vlckova, Pospisil, Cedrik Haškovec, Pavel Burda, Tomas Stopka, Jaroslav Cermak, Peter Laslo
Publikováno v:
Leukemia. 26:1804-1811
Epigenetic 5-azacitidine (AZA) therapy of high-risk myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML) represents a promising, albeit not fully understood, approach. Hematopoietic transcription factor PU.1 is dynamically regulated b
Autor:
Tomas Stopka, Libor Stanek, Filipp Savvulidi, Martina Kapalova, Ulrich Steidl, Karin Vargova, Pavel Burda, Petra Vlckova
Publikováno v:
Blood. 120:769-769
Abstract 769 Introduction: Downregulation of tumour suppressor transcription factor PU.1 in haematopoietic stem and progenitor cells represents primary underlying mechanism for the development of acute myeloid leukaemia (AML) in mice with homozygous