Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Petra Sehnalová"'
Autor:
Arigela Harikumar, Raghu Ram Edupuganti, Matan Sorek, Gajendra Kumar Azad, Styliani Markoulaki, Petra Sehnalová, Soňa Legartová, Eva Bártová, Shlomit Farkash-Amar, Rudolf Jaenisch, Uri Alon, Eran Meshorer
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1304-1314 (2017)
Embryonic stem cells (ESCs), with their dual capacity to self-renew and differentiate, are commonly used to study differentiation, epigenetic regulation, lineage choices, and more. Using non-directed retroviral integration of a YFP/Cherry exon into m
Externí odkaz:
https://doaj.org/article/d8c7170f17f64996acc876ed0d2be165
Autor:
Eva Bártová, Thomas Küntziger, Dušan Cmarko, Philippe Collas, Ivan Raška, Soňa Legartová, Stanislav Kozubek, Dmitry V. Sorokin, Petra Sehnalová, Barbora Malyšková
Publikováno v:
Journal of Cellular Biochemistry. 117:2583-2596
We studied epigenetics, distribution pattern, kinetics, and diffusion of proteins recruited to spontaneous and g-radiation-induced DNA lesions. We showed that PML deficiency leads to an increased number of DNA lesions, which was accompanied by change
Advanced Image Acquisition and Analytical Techniques for Studies of Living Cells and Tissue Sections
Autor:
Jana Krejčí, Michal Franek, Soňa Legartová, Eva Bártová, Petra Sehnalová, Jana Suchánková, Stanislav Kozubek, Josef Večeřa, Dmitry V. Sorokin
Publikováno v:
Microscopy and Microanalysis. 22:326-341
Studies on fixed samples or genome-wide analyses of nuclear processes are useful for generating snapshots of a cell population at a particular time point. However, these experimental approaches do not provide information at the single-cell level. Gen
Autor:
Eva Bártová, Soňa Legartová, Thomas Küntziger, Petra Sehnalová, Stanislav Kozubek, Jana Suchánková
Publikováno v:
Biology of the Cell. 107:440-454
Background Information The DNA damage response is a fundamental, well-regulated process that occurs in the genome to recognise DNA lesions. Here, we studied kinetics of proteins involved in DNA repair pathways and their recruitment to DNA lesions dur
Autor:
Siarhei A. Dabravolski, Petra Sehnalová, Jan Hejátko, Zbyněk Zdráhal, Eva Pagáčová, Lenka Stixová, Stanislav Kozubek, Gabriela Lochmanová, Eva Bártová, Soňa Legartová, Jana Krejčí
Publikováno v:
Journal of Cellular Biochemistry. 116:2195-2209
We examined the levels and distribution of post-translationally modified histones and protamines in human sperm. Using western blot immunoassay, immunofluorescence, mass spectrometry (MS), and FLIM-FRET approaches, we analyzed the status of histone m
Autor:
Stanislav Kozubek, Dmitry V. Sorokin, Soňa Legartová, Eva Bártová, Jana Suchánková, Veronika Foltánková, Petra Sehnalová
Publikováno v:
Nucleus. 5:269-277
Cajal bodies are important nuclear structures containing proteins that preferentially regulate RNA-related metabolism. We investigated the cell-type specific nuclear distribution of Cajal bodies and the level of coilin, a protein of Cajal bodies, in
Publikováno v:
Biology of the Cell. 106:151-165
Background Information The optimal repair of DNA lesions is fundamental for physiological processes. We asked whether the recruitment of HP1β, 53BP1 and BMI1 proteins to ultraviolet (UVA)-induced DNA lesions requires functional A-type lamins. Result
Publikováno v:
Journal of Cellular Biochemistry. 115:476-487
A- and C-type lamins are intermediate filament proteins responsible for the maintenance of nuclear shape and most likely nuclear architecture. Here, we propose that pronounced invaginations of A/C-type lamins into the nuclear interior represent chann
Autor:
Soňa, Legartová, Petra, Sehnalová, Barbora, Malyšková, Thomas, Küntziger, Philippe, Collas, Dušan, Cmarko, Ivan, Raška, Dmitry V, Sorokin, Stanislav, Kozubek, Eva, Bártová
Publikováno v:
Journal of cellular biochemistry. 117(11)
We studied epigenetics, distribution pattern, kinetics, and diffusion of proteins recruited to spontaneous and γ-radiation-induced DNA lesions. We showed that PML deficiency leads to an increased number of DNA lesions, which was accompanied by chang
Autor:
Pavel Matula, Stanislav Kozubek, Dmitry V. Sorokin, Eva Bártová, Magdalena Skalníková, Lenka Stixová, Jana Suchánková, Soňa Legartová, Ivan Raška, Pavel Šimara, Petra Sehnalová
The nucleolus is a well-organized site of ribosomal gene transcription. Moreover, many DNA repair pathway proteins, including ATM, ATR kinases, MRE11, PARP1 and Ku70/80, localize to the nucleolus (Moore et al., 2011 ). We analyzed the consequences of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68048f0f80dabcaa59c905f99f41f5c4
https://europepmc.org/articles/PMC4615213/
https://europepmc.org/articles/PMC4615213/