Zobrazeno 1 - 10
of 530
pro vyhledávání: '"Petra Schwille"'
Autor:
Thomas Litschel, Charlotte F. Kelley, Xiaohang Cheng, Leon Babl, Naoko Mizuno, Lindsay B. Case, Petra Schwille
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Focal adhesions form liquid-like assemblies around activated integrin receptors at the plasma membrane. How they achieve their flexible properties is not well understood. Here, we use recombinant focal adhesion proteins to reconstitute the c
Externí odkaz:
https://doaj.org/article/d61255bf311b4801a31da5e451c31dfa
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Recently, utilization of Machine Learning (ML) has led to astonishing progress in computational protein design, bringing into reach the targeted engineering of proteins for industrial and biomedical applications. However, the design of prote
Externí odkaz:
https://doaj.org/article/7615e1ee231d49e5b6275ae1876afd03
Autor:
Christian Niederauer, Chikim Nguyen, Miles Wang-Henderson, Johannes Stein, Sebastian Strauss, Alexander Cumberworth, Florian Stehr, Ralf Jungmann, Petra Schwille, Kristina A. Ganzinger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract DNA-PAINT based single-particle tracking (DNA-PAINT-SPT) has recently significantly enhanced observation times in in vitro SPT experiments by overcoming the constraints of fluorophore photobleaching. However, with the reported implementation
Externí odkaz:
https://doaj.org/article/3a3bec7bafd14fcaa33cdfd980b5e235
Autor:
Beatrice Ramm, Dominik Schumacher, Andrea Harms, Tamara Heermann, Philipp Klos, Franziska Müller, Petra Schwille, Lotte Søgaard-Andersen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Cell division is spatiotemporally precisely regulated, but the underlying mechanisms are incompletely understood. In the social bacterium Myxococcus xanthus, the PomX/PomY/PomZ proteins form a single megadalton-sized complex that directly po
Externí odkaz:
https://doaj.org/article/ab4adfac3a5f4b9abad4a25d7d3e4627
Autor:
Frederik Steiert, Peter Schultz, Siegfried Höfinger, Thomas D. Müller, Petra Schwille, Thomas Weidemann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
It is challenging to approach protein structures in living cells. Here the authors investigate Interleukin-4 receptor alpha, which has a noncanonical amino acid incorporated at different locations, and see that evaluating click efficiency with calibr
Externí odkaz:
https://doaj.org/article/15d091ccc2a44bd68688832efcdaf1be
Periodic temperature changes drive the proliferation of self-replicating RNAs in vesicle populations
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
How primordial cells could achieve inheritance of encapsulated components is still an open question. Here, the authors show that ribozymes can assemble in active forms and replicate in populations of membrane vesicles thanks to freeze-thaw cycles.
Externí odkaz:
https://doaj.org/article/26332a316667461caa46f0aaad9b30f3
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Constructing a minimal protein machinery for self-division of membrane compartments is a major goal of bottom-up synthetic biology. Here, authors achieved the assembly, placement and onset of contraction of a minimal division ring in lipid vesicles.
Externí odkaz:
https://doaj.org/article/900b1408285d4f4bacd6bc6c0b667e6c
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Liquid–liquid phase separation is a fundamental biophysical process to organize eukaryotic and prokaryotic cytosols. While many biomolecular condensates are formed in the vicinity of, or even on lipid membranes, little is known about the i
Externí odkaz:
https://doaj.org/article/c59b31cb778148e7b670480d6ccc6625
Autor:
Huan Sun, Haiyang Jia, Olivia Kendall, Jovan Dragelj, Vladimir Kubyshkin, Tobias Baumann, Maria-Andrea Mroginski, Petra Schwille, Nediljko Budisa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Sun et al. has studied the genetically encodable halotyrosines in proteins of the prokaryotic cell division machinery to elucidate the general role of halogenation in cellular lifespan and oxidative damage-induced diseases such as aging and cancer.
Externí odkaz:
https://doaj.org/article/16c257434def474fb0e926ce48e5732a
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 15, Pp n/a-n/a (2023)
Abstract Self‐assembly of biological molecules and structures is a fundamental property of life. Whereas most biological functions are based on self‐assembled proteins and protein complexes, the self‐assembly of lipids is important for the spat
Externí odkaz:
https://doaj.org/article/49a798b5828b425c942265a542eabc55