Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Petra Ross"'
Autor:
Ziad Bakouny, David A. Braun, Sachet A. Shukla, Wenting Pan, Xin Gao, Yue Hou, Abdallah Flaifel, Stephen Tang, Alice Bosma-Moody, Meng Xiao He, Natalie Vokes, Jackson Nyman, Wanling Xie, Amin H. Nassar, Sarah Abou Alaiwi, Ronan Flippot, Gabrielle Bouchard, John A. Steinharter, Pier Vitale Nuzzo, Miriam Ficial, Miriam Sant’Angelo, Juliet Forman, Jacob E. Berchuck, Shaan Dudani, Kevin Bi, Jihye Park, Sabrina Camp, Maura Sticco-Ivins, Laure Hirsch, Sylvan C. Baca, Megan Wind-Rotolo, Petra Ross-Macdonald, Maxine Sun, Gwo-Shu Mary Lee, Steven L. Chang, Xiao X. Wei, Bradley A. McGregor, Lauren C. Harshman, Giannicola Genovese, Leigh Ellis, Mark Pomerantz, Michelle S. Hirsch, Matthew L. Freedman, Michael B. Atkins, Catherine J. Wu, Thai H. Ho, W. Marston Linehan, David F. McDermott, Daniel Y. C. Heng, Srinivas R. Viswanathan, Sabina Signoretti, Eliezer M. Van Allen, Toni K. Choueiri
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Sarcomatoid and rhabdoid tumours are highly aggressive forms of renal cell carcinoma that are also responsive to immunotherapy. In this study, the authors perform a comprehensive molecular characterization of these tumours discovering an enrichment o
Externí odkaz:
https://doaj.org/article/65b689f6ed0042b1ab0807dd0eb2f0de
Autor:
Jin Yao, Thomas Powles, David F McDermott, Toni K Choueiri, Petra Ross-MacDonald, Simon Papillon-Cavanagh, Robert J Motzer, M Brent McHenry, Megan Wind-Rotolo, Ron Ammar, Yann-Alexandre Vano, Saurabh Gupta, Celine Han, Shruti S Saggi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background The phase 3 CheckMate 214 trial demonstrated higher response rates and improved overall survival with nivolumab plus ipilimumab versus sunitinib in first-line therapy for advanced clear-cell renal cell carcinoma (RCC). An unmet need exists
Externí odkaz:
https://doaj.org/article/1e556bbcc49144c39a159ece4d4fdec1
Autor:
David F McDermott, Gordon J Freeman, Toni K Choueiri, Petra Ross-MacDonald, F Stephen Hodi, Megan Wind-Rotolo, Long Yuan, Kathleen M Mahoney, Linan Song, Eliseo Veras
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Soluble PD-L1 (sPD-L1) has been associated with worse prognosis in numerous solid tumors. We determined sPD-L1 levels before and during nivolumab treatment in two prospective clinical trials of metastatic clear cell renal cell carcinoma (R
Externí odkaz:
https://doaj.org/article/7c93c3e786c84292b00ec79f0d4a49f9
Autor:
Mario Sznol, Toni K Choueiri, Scott D Chasalow, Petra Ross-MacDonald, Simon Papillon-Cavanagh, Alice M Walsh, Megan Wind-Rotolo, Ron Ammar, Peter M Szabo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Nivolumab is an immune checkpoint inhibitor targeting the programmed death-1 receptor that improves survival in a subset of patients with clear cell renal cell carcinoma (ccRCC). In contrast to other tumor types that respond to immunothera
Externí odkaz:
https://doaj.org/article/2e6e7ac70cb64051a3880d53c7fc409f
Autor:
Elisabeth K.M. Mack, André Marquardt, Danny Langer, Petra Ross, Alfred Ultsch, Michael G. Kiehl, Hildegard I.D. Mack, Torsten Haferlach, Andreas Neubauer, Cornelia Brendel
Publikováno v:
Haematologica, Vol 104, Iss 2 (2019)
Differential induction therapy of all subtypes of acute myeloid leukemia other than acute promyelocytic leukemia is impeded by the long time required to complete complex and diverse cytogenetic and molecular genetic analyses for risk stratification o
Externí odkaz:
https://doaj.org/article/a1050238b8c74a2aa6b4d93eaf0b117e
Autor:
Cornelia Brendel, Sabine Teichler, Axel Millahn, Thorsten Stiewe, Michael Krause, Kathleen Stabla, Petra Ross, Minh Huynh, Thomas Illmer, Marco Mernberger, Christina Barckhausen, Andreas Neubauer
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123181 (2015)
RAS mutations are frequently found among acute myeloid leukemia patients (AML), generating a constitutively active signaling protein changing cellular proliferation, differentiation and apoptosis. We have previously shown that treatment of AML patien
Externí odkaz:
https://doaj.org/article/ca5657a754f64fcba645922ceb1ef248
Autor:
Jacques Friborg, Petra Ross-Macdonald, Jian Cao, Ryan Willard, Baiqing Lin, Betsy Eggers, Fiona McPhee
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121734 (2015)
Peginterferon lambda-1a (Lambda), a type III interferon (IFN), acts through a unique receptor complex with limited cellular expression outside the liver which may result in a differentiated tolerability profile compared to peginterferon alfa (alfa).
Externí odkaz:
https://doaj.org/article/4e61aabd88184df9a5a91944e37ab7ed
Autor:
Rui-Ru Ji, Heshani de Silva, Yisheng Jin, Robert E Bruccoleri, Jian Cao, Aiqing He, Wenjun Huang, Paul S Kayne, Isaac M Neuhaus, Karl-Heinz Ott, Becky Penhallow, Mark I Cockett, Michael G Neubauer, Nathan O Siemers, Petra Ross-Macdonald
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 9, p e1000512 (2009)
The dose response curve is the gold standard for measuring the effect of a drug treatment, but is rarely used in genomic scale transcriptional profiling due to perceived obstacles of cost and analysis. One barrier to examining transcriptional dose re
Externí odkaz:
https://doaj.org/article/2200014703f348538cb5cd6ad646b99a
Autor:
Kevin Fitzgerald, Svetlana Tertyshnikova, Lisa Moore, Lynn Bjerke, Ben Burley, Jian Cao, Pamela Carroll, Robert Choy, Steve Doberstein, Yves Dubaquie, Yvonne Franke, Jenny Kopczynski, Hendrik Korswagen, Stanley R Krystek, Nicholas J Lodge, Ronald Plasterk, John Starrett, Terry Stouch, George Thalody, Honey Wayne, Alexander van der Linden, Yongmei Zhang, Stephen G Walker, Mark Cockett, Judi Wardwell-Swanson, Petra Ross-Macdonald, Rachel M Kindt
Publikováno v:
PLoS Genetics, Vol 2, Iss 4, p e57 (2006)
We report here on a chemical genetic screen designed to address the mechanism of action of a small molecule. Small molecules that were active in models of urinary incontinence were tested on the nematode Caenorhabditis elegans, and the resulting phen
Externí odkaz:
https://doaj.org/article/1932641b9cd346b58d4f8941da49cf1f
Autor:
Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart
Microarray data for the 5 probe sets that show differential responses to JQ1 treatment. Shown are the Affymetrix RMA anti-log values of probe intensity with each treatment, together with the fold change in signal from JQ1 treatment and the JQ1 concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7facb10562e6d7eeda3f57ecf51d390b
https://doi.org/10.1158/1535-7163.22501642
https://doi.org/10.1158/1535-7163.22501642
