Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Petra Prijatelj-Žnidaršič"'
Publikováno v:
Toxin Reviews. 33:42-47
Anti-coagulant FXa-binding Viperidae snake venom phospholipases A2 (sPLA2) have been identified as specific, exogenous, non-competitive FXa-inhibitors. Detailed knowledge of the sites of interaction of PLA2 with FXa is essential for understanding the
Autor:
Petra Prijatelj-Žnidaršič, Brigitte Vulliez-Le Normand, Frederick Saul, Joze Pungercar, Igor Križaj, Grazyna Faure, Bertrand Raynal, Benoit Villette
Publikováno v:
Journal of Structural Biology. 169:360-369
Ammodytoxin A (AtxA) and its natural isoform AtxC from the venom of Vipera ammodytes ammodytes belong to group IIA-secreted phospholipases A2 which catalyze the hydrolysis of glycerophospholipids and exhibit strong neurotoxic and anticoagulant effect
Publikováno v:
Genetic Manipulation of DNA and Protein-Examples from Current Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdea192fc90cfb1d9bdee643ed88222
http://www.intechopen.com/articles/show/title/protein-engineering-in-structure-function-studies-of-viper-s-venom-secreted-phospholipases-a2
http://www.intechopen.com/articles/show/title/protein-engineering-in-structure-function-studies-of-viper-s-venom-secreted-phospholipases-a2
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 59(6)
Ammodytoxin A (AtxA) is the most toxic secreted phospholipase A 2 of the three isotoxins with presynaptic neurotoxicity, isolated from the venom of the nose-horned viper ( Vipera ammodytes ammodytes ), with an LD 50 of 21 μg/kg in mice. The toxic po