Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Petra Pfeiffer"'
Publikováno v:
Proceedings of the 15th CONTECSI International Conference on Information Systems and Technology Management.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59db5afe5fccb3cc8c4bb8e85bfe17a3
https://doi.org/10.5748/9788599693148-15contecsi/ps-5661
https://doi.org/10.5748/9788599693148-15contecsi/ps-5661
Autor:
Johannes H. Schulte, Ludger Klein-Hitpass, Angelika Eggert, Petra Pfeiffer, Denis Biard, Steffi Kuhfittig-Kulle, Alexander Schramm
Publikováno v:
DNA Repair. 7:1757-1764
In the childhood tumor neuroblastoma, high expression of the TrkA neurotrophin receptor is associated with a favorable prognosis and a lack of structural chromosomal changes, whereas TrkB is expressed in aggressive neuroblastomas demonstrating high g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7be136fcb82c6b7c2f3ee62e0d31f4a
https://doi.org/10.1016/j.dnarep.2008.07.004
https://doi.org/10.1016/j.dnarep.2008.07.004
Autor:
Denis Biard, Steffi Kuhfittig-Kulle, Bernard Salles, Emmanuelle Despras, Jaime F. Angulo, Petra Pfeiffer, Patrick Calsou
Publikováno v:
Cancer Research. 67:2526-2534
To study the relationships between different DNA repair pathways, we established a set of clones in which one specific DNA repair gene was silenced using long-term RNA interference in HeLa cell line. We focus here on genes involved in either nucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fedfa824cd6195368b467848f7d76e
https://doi.org/10.1158/0008-5472.can-06-3371
https://doi.org/10.1158/0008-5472.can-06-3371
Autor:
Gustavo A. Folle, Petra Pfeiffer, A.T. Natarajan, P Jeppesen, Wilner Martínez-López, Christian Johannes, Máximo E. Drets, John R.K. Savage, G. Obe, Wolfgang Goedecke
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 504:17-36
Chromosomal aberrations (CA) are the microscopically visible part of a wide spectrum of DNA changes generated by different repair mechanisms of DNA double strand breaks (DSB). The method of fluorescence in situ hybridisation (FISH) has uncovered unex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428a32b363799455e0332ba85edd6dcd
https://doi.org/10.1016/s0027-5107(02)00076-3
https://doi.org/10.1016/s0027-5107(02)00076-3
Autor:
Petra Pfeiffer, Elke Feldmann, Wolfgang Goedecke, Christian Schunck, Ronald D. Neumann, Andrea Odersky, Igor G. Panyutin, Irina V. Panyutin, Guenter Obe
Publikováno v:
Journal of Biological Chemistry. 277:11756-11764
In mammalian cells, nonhomologous DNA end joining (NHEJ) is considered the major pathway of double-strand break (DSB) repair. Rejoining of DSB produced by decay of (125)I positioned against a specific target site in plasmid DNA via a triplex-forming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34bcaf98ce3b9e19f2ab3c9eb08dc02f
https://doi.org/10.1074/jbc.m111304200
https://doi.org/10.1074/jbc.m111304200
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1105
Double-strand breaks (DSB) in genomic DNA are induced by ionizing radiation or radiomimetic drugs but also occur spontaneously during the cell cycle at quite significant frequencies. In vertebrate cells, nonhomologous DNA end joining (NHEJ) is consid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0452a228aa2eaeffcea1341e8e7c6e1f
https://pubmed.ncbi.nlm.nih.gov/24623253
https://pubmed.ncbi.nlm.nih.gov/24623253
Autor:
Tong Zhou, Jae-Wan Lee, Petra Pfeiffer, Michele F. Hannah, Shuang Chen, Lawrence F. Povirk, Susan P. Lees-Miller, Elke Feldmann, Kedar V. Inamdar, Yin Yu
Publikováno v:
Journal of Biological Chemistry. 276:24323-24330
To examine determinants of fidelity in DNA end joining, a substrate containing a model of a staggered free radical-mediated double-strand break, with cohesive phosphoglycolate-terminated 3'-overhangs and a one-base gap in each strand, was constructed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e908fb0aa273e6f49a6654ac6e53949
https://doi.org/10.1074/jbc.m010544200
https://doi.org/10.1074/jbc.m010544200
Publikováno v:
Mutagenesis. 15:289-302
DNA double-strand breaks (DSB) are considered to be critical primary lesions in the formation of chromosomal aberrations. DSB may be induced by exogenous agents, such as ionizing radiation, but also occur spontaneously during cellular processes at qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1f105e7b61bea6cda22cc41414941e
https://doi.org/10.1093/mutage/15.4.289
https://doi.org/10.1093/mutage/15.4.289
Publikováno v:
Nucleic Acids Research. 28:2585-2596
Non-homologous DNA end joining (NHEJ) is considered the major pathway of double-strand break (DSB) repair in mammalian cells and depends, among other things, on the DNA end-binding Ku70/80 hetero-dimer. To investigate the function of Ku in NHEJ we ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69ed72450cc6be7e6f304d3e2bb7c25
https://doi.org/10.1093/nar/28.13.2585
https://doi.org/10.1093/nar/28.13.2585
Autor:
Petra Pfeiffer
Publikováno v:
Toxicology Letters. :119-129
Numerous environmental pollutants are considered DNA-damaging agents with defined mutagenic potential. Therefore, toxicological studies have focused mainly on the impact of such substances on human health, mutagenesis and carcinogenesis. The possible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485bb87a27a3e7c95a4249d226b63acd
https://doi.org/10.1016/s0378-4274(98)00058-7
https://doi.org/10.1016/s0378-4274(98)00058-7