Comorbidity burden in adult atopic dermatitis: A population‐based study

Autor: Jacob P. Thyssen, Dan Henrohn, Maureen P. Neary, Kirk Geale, Alexander R. Dun, Gustaf Ortsäter, Ingrid Lindberg, Anna De Geer, Petra Neregård, Amy Cha, Joseph C. Cappelleri, William Romero, Laura vonKobyletzki

Publikováno v: JEADV Clinical Practice, Vol 3, Iss 1, Pp 128-141 (2024)

Abstract Background Atopic dermatitis (AD) is a chronic inflammatory skin disease that has been shown to be associated with allergic comorbidities. However, studies examining comorbidities in patients with AD are incomplete, which may contribute to s

Externí odkaz: https://doaj.org/article/682733713428468e82be9f706d9b21ba

Validation of Patient Identification Algorithms for Atopic Dermatitis Using Healthcare Databases

Autor: Gustaf Ortsäter, Anna De Geer, Kirk Geale, Alexander Rieem Dun, Ingrid Lindberg, Jacob P. Thyssen, Laura von Kobyletzki, Natalia Ballardini, Dan Henrohn, Petra Neregård, Amy Cha, Joseph C. Cappelleri, Maureen P. Neary

Publikováno v: Ortsäter, G, De Geer, A, Geale, K, Rieem Dun, A, Lindberg, I, Thyssen, J P, von Kobyletzki, L, Ballardini, N, Henrohn, D, Neregård, P, Cha, A, Cappelleri, J C & Neary, M P 2022, ' Validation of Patient Identification Algorithms for Atopic Dermatitis Using Healthcare Databases ', Dermatology and Therapy, vol. 12, no. 2, pp. 545-559 . https://doi.org/10.1007/s13555-021-00670-1

Introduction: The use of real-world data offers a possibility to perform large-scale epidemiological studies in actual clinical settings. Despite their many advantages, administrative databases were not designed to be used in research, and the valida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05279ee0ec777835d936659a677b733
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-485444

The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats

Autor: Liselotte Bäckdahl, Anca I. Catrina, Markus H. Hoffmann, Birgitta Agerberth, Petra Neregård, Rikard Holmdahl, Martin Herrmann, Birgit Niederreiter, Heiko Bruns

Publikováno v: Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases; Vol 72

BackgroundIn rheumatoid arthritis (RA), neutrophil granulocytes fuel inflammation and damage tissue in the joint by releasing cytotoxic agents, antimicrobial peptides, proteases and other inflammatory mediators. The human cathelicidin LL-37 has recen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f15db5110cfc65faa2bf705e43ea617
https://opus4.kobv.de/opus4-fau/files/7849/Hoffmann_the_cathelicidins.pdf

Childbearing and the risk of scleroderma: a population-based study in Sweden

Autor: Lena Björnådal, Petra Neregård, Mats Lambe, Glinda S. Cooper, Olof Nyrén

Publikováno v: American journal of epidemiology. 159(2)

This study examined associations between childbearing and risk of scleroderma by using national population-based registry data from Sweden. Women with a discharge diagnosis of scleroderma from 1964 to 1999 (n = 2,149) were identified in the Swedish I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0766a5b7adaed0a1450fd20248daa2
https://pubmed.ncbi.nlm.nih.gov/14718218

LL-37 is expressed in the inflamed synovium in patients with rheumatoid arthritis and downregulated by TNF inhibitors

Autor: Petra Neregård, Anca I. Catrina, Birgitta Agerberth, Marianne Engström

Publikováno v: Annals of the Rheumatic Diseases. 71:A12.1-A12

Background/objectives LL-37, a member of the cathelicidin family of host defense peptides, has a broad range of immunomodulatory and anti-infective effects that are known to selectively alter innate immunity. The authors aimed to investigate a potent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b3a75f61b5629fe61db5c65801246f3
https://doi.org/10.1136/annrheumdis-2011-201230.26