Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Petra Mrozkova"'
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background Opioid analgesics remain widely used for pain treatment despite the related serious side effects. Some of those, such as opioid tolerance and opioid-induced hyperalgesia may be at least partially due to modulation of opioid recept
Externí odkaz:
https://doaj.org/article/283da2c846314e67b4b0e0c8da04c39f
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163991 (2016)
Protease-activated receptors 2 (PAR2) and transient receptor potential vanilloid 1 (TRPV1) receptors in the peripheral nerve endings are implicated in the development of increased sensitivity to mechanical and thermal stimuli, especially during infla
Externí odkaz:
https://doaj.org/article/360f5e9fa9e8498f85c48ef039c04657
Publikováno v:
Current Tissue Microenvironment Reports. 1:23-29
Purpose of Review Chronic pain is a distressing condition that is ineffectively treated at present. In order to develop novel, more efficacious analgesics for chronic pain, a better understanding of the underlying mechanisms is required. Despite chro
Publikováno v:
Journal of neuroinflammation, Vol. 18, no.1, p. 279 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-11 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-11 (2021)
Background Opioid analgesics remain widely used for pain treatment despite the related serious side effects. Some of those, such as opioid tolerance and opioid-induced hyperalgesia may be at least partially due to modulation of opioid receptors (OR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f35c8dc085bd7a24db4e7045cf0b53
https://hdl.handle.net/2078.1/270613
https://hdl.handle.net/2078.1/270613
Publikováno v:
British Journal of Pharmacology. 175:2322-2336
Background and Purpose Endocannabinoids play an important role in modulating spinal nociceptive signalling, crucial for the development of pain. The cannabinoid receptor 1 (CB1) and the transient receptor potential cation channel subfamily V member 1
Publikováno v:
Neuropharmacology. 81:75-84
Modulation of nociceptive synaptic transmission in the spinal cord is implicated in the development and maintenance of several pathological pain states. The chemokine CCL2 (C–C motif ligand 2) was shown to be an important factor in the development
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0163991 (2016)
PLoS ONE, Vol 11, Iss 10, p e0163991 (2016)
Protease-activated receptors 2 (PAR2) and transient receptor potential vanilloid 1 (TRPV1) receptors in the peripheral nerve endings are implicated in the development of increased sensitivity to mechanical and thermal stimuli, especially during infla
Publikováno v:
Physiological research. 65(3)
Protease-activated receptors (PARs) belong to the G-protein-coupled receptor family, that are expressed in many body tissues especially in different epithelial cells, mast cells and also in neurons and astrocytes. PARs play different physiological ro
Autor:
Abdul Basit Jawad, Claudio E. Tatsui, Juan P. Cata, Hongmei Zhang, Haijun Zhang, Ross M. Kennamer-Chapman, Daniel S. Harrison, Kenneth Sapire, Petra Mrozkova, Jiusheng Yan, Qin Li, Patrick M. Dougherty, Jiri Palecek, Ryan M. Cassidy, Laurence D. Rhines, Yan Li, Alyssa K. Kosturakis, Pavel Adamek, Andrea Ghetti
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(39)
Peripheral neuropathy is dose limiting in paclitaxel cancer chemotherapy and can result in both acute pain during treatment and chronic persistent pain in cancer survivors. The hypothesis tested was that paclitaxel produces these adverse effects at l