Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Petra Malmberg-Aiello"'
Autor:
Alessandro Bartolini, Carla Ghelardini, Walter Schunack, Petra Malmberg-Aiello, Nicoletta Galeotti
Publikováno v:
Neuropharmacology. 47:295-303
The supraspinal cellular events involved in H(1)-mediated hyperalgesia were investigated in a condition of acute thermal pain by means of the mouse hot-plate test. I.c.v. administration of the phospholipase C (PLC) inhibitors U-73122 and neomycin ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0891e0bdbf55eb767356853fb140460
https://doi.org/10.1016/j.neuropharm.2004.03.013
https://doi.org/10.1016/j.neuropharm.2004.03.013
Publikováno v:
Pharmacology Biochemistry and Behavior. 71:313-318
Effects of substances that are able to alter the histamine level, a histamine H(1)-receptor agonist and antagonist, and a histamine H(2)-receptor agonist were investigated in an anxiety-like state in mice by means of the light/dark box test. Diazepam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81611edd83976ac4a7093a713a620108
https://doi.org/10.1016/s0091-3057(01)00691-8
https://doi.org/10.1016/s0091-3057(01)00691-8
Autor:
Silvia Selleri, Barbara Costa, Antonio Lucacchini, Alessandra Ipponi, Claudia Martini, Fabrizio Bruni, Petra Malmberg Aiello, Gabriella Guerrini, Annarella Costanzo, Giovanna Ciciani
Publikováno v:
Journal of Medicinal Chemistry. 42:2218-2226
The synthesis of new 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2, 4]benzotriazine 5-oxides and their binding activities at the central benzodiazepine receptor (BZR) are reported. The derivatives substituted at the 3-position with electron-rich five-memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1510c0723142483b30a211698feec60
https://doi.org/10.1021/jm981126y
https://doi.org/10.1021/jm981126y
Autor:
Alessandra Ipponi, Claudia Lamberti, Petra Malmberg-Aiello, Alessandro Bartolini, Antonio Medica
Publikováno v:
European Journal of Pharmacology. 368:205-211
The effects of a new antiepileptic drug, tiagabine, (R)-N-[4,4-di-(3-methylthien-2-yl)but-3-enyl] nipecotic acid hydrochloride, were studied in mice and rats in antinociceptive tests, using three kinds of noxious stimuli: mechanical (paw pressure), c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40053f7015c7498960dc12de6a7e9a3d
https://doi.org/10.1016/s0014-2999(99)00034-5
https://doi.org/10.1016/s0014-2999(99)00034-5
Autor:
Alessandro Ipponi, Walter Schunack, Petra Malmberg-Aiello, Claudia Lamberti, Alessandro Bartolini
Publikováno v:
British Journal of Pharmacology. 123:1331-1336
Effects of substances which are able to alter brain histamine levels and two histamine H1 receptor agonists were investigated in mice by means of an animal model of depression, the forced swim test. Imipramine (10 and 30 mg kg−1, i.p.) and amitript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::467c220cf4b7d7e0cb51afea33559bd0
https://doi.org/10.1038/sj.bjp.0701740
https://doi.org/10.1038/sj.bjp.0701740
Autor:
Petra Malmberg-Aiello, Alberto Giotti, Claudia Lamberti, Alessandro Bartolini, Carla Ghelardini
Publikováno v:
British Journal of Pharmacology. 111:1269-1279
1. Effects of substances which are able to alter brain histamine levels on the nociceptive threshold were investigated in mice and rats by means of tests inducing three different kinds of noxious stimuli: mechanical (paw pressure), chemical (abdomina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f67da1f7e9b424e1b6a15071c86268
https://doi.org/10.1111/j.1476-5381.1994.tb14883.x
https://doi.org/10.1111/j.1476-5381.1994.tb14883.x
Autor:
Fabrizio Bruni, Petra Malmberg Aiello, Annarella Costanzo, Gabriella Guerrini, Silvia Selleri, Claudia Lamberti
Publikováno v:
Journal of Heterocyclic Chemistry. 29:1499-1505
The synthesis of derivatives of pyrazolo[1,5-a]pyrrolo[1,2-c][1,3,6]benzotriazocine was obtained by the reaction of arylaldehydes with some 1-(2-aminophenyl)-5-(pyrrol-1-yl)pyrazoles, as hydrochlorides. Characterization of this new class of compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2beca8bcbeed7c0842882efff53c5daf
https://doi.org/10.1002/jhet.5570290621
https://doi.org/10.1002/jhet.5570290621
Autor:
Carla Ghelardini, M. Malcangio, L. Fantetti, A. Bartolini, Alberto Giotti, Petra Malmberg-Aiello
Publikováno v:
British Journal of Pharmacology. 105:77-82
1. The ability to modify the pain threshold by the two M1-muscarinic agonists: McN-A-343 and AF-102B and by the specific M2-agonist arecaidine was examined in mice and rats by using three different noxious stimuli: chemical (writhing test), thermic (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01b9e7a426b8bb77832bffc1f99cf11
https://doi.org/10.1111/j.1476-5381.1992.tb14213.x
https://doi.org/10.1111/j.1476-5381.1992.tb14213.x
Publikováno v:
British Journal of Pharmacology. 101:49-54
1. The effect of atropine on the nociceptive system was examined in mice and rats by use of the hot-plate, writhing and tail-flick tests. 2. Atropine dose-dependently produced analgesia, no effect and hyperalgesia. Analgesia was observed in both spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca619c28b3717ef534543ed5eb4ae49
https://doi.org/10.1111/j.1476-5381.1990.tb12087.x
https://doi.org/10.1111/j.1476-5381.1990.tb12087.x
Autor:
François Besnard, Claudia Martini, Barbara Costa, Camilla Costagli, Giovanna Ciciani, Petra Malmberg Aiello, Gabriella Guerrini, Silvia Selleri, Marina Montali, Gaetano De Siena, Annarella Costanzo, Paola Gratteri, Jonna Fohlin, Fabrizio Bruni
Publikováno v:
Journal of medicinal chemistry. 48(21)
In our pursuit to identify selective ligands for Bz/GABA(A) receptor subtypes, a novel pyrazolo[1,5-a]pyrimidine derivative (4), the azaisostere of zolpidem, was synthesized and evaluated in vitro on bovine brain homogenate and on recombinant benzodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9fc7547b4166d28424f84163af5f8ac
https://pubmed.ncbi.nlm.nih.gov/16220991
https://pubmed.ncbi.nlm.nih.gov/16220991