Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Petra M. Färber"'
1
Molecular and Biochemical Characterization of a Plasmodium Falciparum Cyclophilin Containing a Cleavable Signal Sequence
Autor: Richard M. Franklin, Angus Bell, Petra M. Färber, Jocelyne Hirtzlin
Publikováno v: European Journal of Biochemistry. 232:765-772
The immunosuppressive drug cyclosporin A (CsA) inhibits the growth of malaria parasites in vitro and in vivo. Cyclosporin A exerts its immunosuppressive effect in T lymphocytes by binding to cyclophilin (CyP), a peptidylprolyl cis-trans isomerase (PP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7875272edf52858eb4cdfe2f39d361b2
https://doi.org/10.1111/j.1432-1033.1995.0765a.x
Zobrazit plný text záznamu
2
Glutamate dehydrogenase, the marker protein of Plasmodium falciparum . Cloning, expression and characterization of the malarial enzyme
Autor: Jan T. Wagner, Friedrich Lottspeich, R. Luise Krauth-Siegel, Heike Lüdemann, Petra M. Färber
Publikováno v: European Journal of Biochemistry. 258:813-819
The gene of an NADP+-specific glutamate dehydrogenase was cloned from Plasmodium falciparum, the causative agent of tropical malaria. Southern-blot analysis indicates a single-copy gene. The gene encodes a protein with 470 residues which has 50 % of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c7ac964e10bd93ce7c149df453badb
https://doi.org/10.1046/j.1432-1327.1998.2580813.x
Zobrazit plný text záznamu
3
RecombinantPlasmodium falciparumglutathione reductase is inhibited by the antimalarial dye methylene blue
Autor: Petra M. Färber, Katja Becker, Charles H. Williams, R.H. Schirmer, Arscott Ld
Publikováno v: FEBS Letters. 422:311-314
Plasmodium falciparum glutathione reductase (PfGR) has emerged as a drug target against tropical malaria. Here we report the expression of PfGR in Escherichia coli SG5(DE3) and isolation procedures for this protein. Recombinant PfGR does not differ f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588f72b36a2800c91fdf0e3062668381
https://doi.org/10.1016/s0014-5793(98)00031-3
Zobrazit plný text záznamu
4
Molecular cloning and characterization of a second calcium-dependent protein kinase of Plasmodium falciparum1Note: Nucleotide sequence data reported in this paper are available in the EMBL, GenBank™ and DDJB databases under the accession number X99763.1
Autor: Petra M. Färber, Richard M. Franklin, Barbara Kappes, Ralph Graeser
Publikováno v: Molecular and Biochemical Parasitology. 87:211-216
by our andother groups. One of these, PfCPK, belongs to thefamily of calcium-dependent protein kinases(CDPKs), which have only been found in plantsand protists [1,2]. Since CDPKs do not exist invertebrates, they represent promising targets forantimal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4195b989c9e97200cd9ca42c77568aa3
https://doi.org/10.1016/s0166-6851(97)00052-2
Zobrazit plný text záznamu
6
Molecular Cloning and Characterization of a Putative Glutathione Reductase Gene, the PfGR2 Gene, from Plasmodium falciparum
Autor: Petra M. Färber, Sylke Müller, R. Heiner Schirmer, Katja Becker, Richard M. Franklin
Publikováno v: European Journal of Biochemistry. 239:655-661
Recently, glutathione reductase (GR) has emerged as a promising target for antiparasitic drugs. The central role of GR in cellular antioxidant defence, the particular susceptibility of intracellular parasites like Plasmodium falciparum to oxidative s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ad277e7439650d61cac78c37087ae6
https://doi.org/10.1111/j.1432-1033.1996.0655u.x
Zobrazit plný text záznamu
7
In vitro synthesis of West Nile virus proteins indicates that the amino-terminal segment of the NS3 protein contains the active centre of the protease which cleaves the viral polyprotein after multiple basic amino acids
Autor: Johannes H. Hegemann, Gerd Wengler, Petra M. Färber, Gerd Czaya
Publikováno v: Journal of General Virology. 72:851-858
A virus-encoded protease that cleaves after multiple basic amino acid residues has been implicated in the processing of the flavivirus polyprotein. Recently, a computer search of amino acid residues which might form the active site of a protease led
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afe7fdc68ac41c7a7e872132c10e1b0
https://doi.org/10.1099/0022-1317-72-4-851
Zobrazit plný text záznamu
8
Isolation of a novel Plasmodium falciparum gene encoding a protein homologous to the Tat-binding protein family
Autor: Richard M. Franklin, Petra M. Färber, Jocelyne Hirtzlin
Publikováno v: European journal of biochemistry. 226(2)
We have cloned a Plasmodium falciparum gene that belongs to the nuclear Tat-binding protein (TBP) gene family. This gene, PfTBP, is (A + T)-rich and encodes a 49.5-kDa protein. The predicted protein encoded by this gene has highest similarity to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f311274b502344aa3c001bd0ec25117c
https://pubmed.ncbi.nlm.nih.gov/8001584
Zobrazit plný text záznamu
9
Analyses of the terminal sequences of West Nile virus structural proteins and of the in vitro translation of these proteins allow the proposal of a complete scheme of the proteolytic cleavages involved in their synthesis
Autor: Thomas Nowak, Petra M. Färber, Gisela Wengler, Gerd Wengler
Publikováno v: Virology. 169(2)
The proteolytic processes involved in the synthesis of the structural proteins of the West Nile (WN) flavivirus were analyzed: The carboxy-terminal sequences of the structural proteins were determined and the proteins translated in vitro in the prese
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db273bb6e5e8a6693941a5d45190f35c
https://pubmed.ncbi.nlm.nih.gov/2705302
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje