Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Petra M. Färber"'
Publikováno v:
European Journal of Biochemistry. 232:765-772
The immunosuppressive drug cyclosporin A (CsA) inhibits the growth of malaria parasites in vitro and in vivo. Cyclosporin A exerts its immunosuppressive effect in T lymphocytes by binding to cyclophilin (CyP), a peptidylprolyl cis-trans isomerase (PP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7875272edf52858eb4cdfe2f39d361b2
https://doi.org/10.1111/j.1432-1033.1995.0765a.x
https://doi.org/10.1111/j.1432-1033.1995.0765a.x
Publikováno v:
European Journal of Biochemistry. 258:813-819
The gene of an NADP+-specific glutamate dehydrogenase was cloned from Plasmodium falciparum, the causative agent of tropical malaria. Southern-blot analysis indicates a single-copy gene. The gene encodes a protein with 470 residues which has 50 % of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c7ac964e10bd93ce7c149df453badb
https://doi.org/10.1046/j.1432-1327.1998.2580813.x
https://doi.org/10.1046/j.1432-1327.1998.2580813.x
Publikováno v:
FEBS Letters. 422:311-314
Plasmodium falciparum glutathione reductase (PfGR) has emerged as a drug target against tropical malaria. Here we report the expression of PfGR in Escherichia coli SG5(DE3) and isolation procedures for this protein. Recombinant PfGR does not differ f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588f72b36a2800c91fdf0e3062668381
https://doi.org/10.1016/s0014-5793(98)00031-3
https://doi.org/10.1016/s0014-5793(98)00031-3
Publikováno v:
Molecular and Biochemical Parasitology. 87:211-216
by our andother groups. One of these, PfCPK, belongs to thefamily of calcium-dependent protein kinases(CDPKs), which have only been found in plantsand protists [1,2]. Since CDPKs do not exist invertebrates, they represent promising targets forantimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4195b989c9e97200cd9ca42c77568aa3
https://doi.org/10.1016/s0166-6851(97)00052-2
https://doi.org/10.1016/s0166-6851(97)00052-2
Autor:
Katja Becker, Sylke Müller, Rolf D. Walter, Tim-Wolf Gilberger, Petra M. Färber, R.H. Schirmer
Publikováno v:
Molecular and Biochemical Parasitology. 80:215-219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601fe0f95e3e559e9bad0360f494f42a
https://doi.org/10.1016/0166-6851(96)02694-1
https://doi.org/10.1016/0166-6851(96)02694-1
Publikováno v:
European Journal of Biochemistry. 239:655-661
Recently, glutathione reductase (GR) has emerged as a promising target for antiparasitic drugs. The central role of GR in cellular antioxidant defence, the particular susceptibility of intracellular parasites like Plasmodium falciparum to oxidative s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ad277e7439650d61cac78c37087ae6
https://doi.org/10.1111/j.1432-1033.1996.0655u.x
https://doi.org/10.1111/j.1432-1033.1996.0655u.x
Publikováno v:
Journal of General Virology. 72:851-858
A virus-encoded protease that cleaves after multiple basic amino acid residues has been implicated in the processing of the flavivirus polyprotein. Recently, a computer search of amino acid residues which might form the active site of a protease led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afe7fdc68ac41c7a7e872132c10e1b0
https://doi.org/10.1099/0022-1317-72-4-851
https://doi.org/10.1099/0022-1317-72-4-851
Publikováno v:
European journal of biochemistry. 226(2)
We have cloned a Plasmodium falciparum gene that belongs to the nuclear Tat-binding protein (TBP) gene family. This gene, PfTBP, is (A + T)-rich and encodes a 49.5-kDa protein. The predicted protein encoded by this gene has highest similarity to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f311274b502344aa3c001bd0ec25117c
https://pubmed.ncbi.nlm.nih.gov/8001584
https://pubmed.ncbi.nlm.nih.gov/8001584
Publikováno v:
Virology. 169(2)
The proteolytic processes involved in the synthesis of the structural proteins of the West Nile (WN) flavivirus were analyzed: The carboxy-terminal sequences of the structural proteins were determined and the proteins translated in vitro in the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db273bb6e5e8a6693941a5d45190f35c
https://pubmed.ncbi.nlm.nih.gov/2705302
https://pubmed.ncbi.nlm.nih.gov/2705302
