Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Petra L, Sedlak"'
Publikováno v:
Frontiers in Neural Circuits
Frontiers in Neural Circuits, Vol 13 (2019)
Frontiers in Neural Circuits, Vol 13 (2019)
In mammalian neurons, small conductance calcium-activated potassium channels (SK channels) are activated by calcium influx and contribute to the afterhyperpolarization (AHP) that follows action potentials. Three types of SK channel, SK1, SK2 and SK3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a45a873d3caa2f1e94a59c492e4cd51
Publikováno v:
Journal of Neurophysiology. 109:1391-1402
N-methyl-d-aspartate (NMDA) receptors are heteromultimeric ion channels that contain an essential GluN1 subunit and two or more GluN2 (GluN2A–GluN2D) subunits. The biophysical properties and physiological roles of synaptic NMDA receptors are depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1edc0b636be3cbac8faa2b3d7ee637
https://doi.org/10.1152/jn.00176.2012
https://doi.org/10.1152/jn.00176.2012
Publikováno v:
Neuroscience Letters. 469:237-242
The amygdalar complex is a limbic structure that plays a key role in emotional processing and fear conditioning. Although inhibitory transmission in the amygdala is predominately GABA-ergic, neurons of the amygdala are also known to express glycine r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1e4fcbac2d7162ef131bf8531b4d1d
https://doi.org/10.1016/j.neulet.2009.12.003
https://doi.org/10.1016/j.neulet.2009.12.003
Publikováno v:
Neuroscience. 137:781-794
Classical mammalian transient receptor potential channels form non-selective cation channels that open in response to activation of phospholipase C-coupled metabotropic receptors, and are thought to play a key role in calcium homeostasis in non-excit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a20a5a62893ebee7b3dc9664a4b5e1d
https://doi.org/10.1016/j.neuroscience.2005.09.027
https://doi.org/10.1016/j.neuroscience.2005.09.027
Publikováno v:
Journal of Virology. 74:3253-3263
Most of the seven flavivirus nonstructural proteins (NS1 to NS5) encoded in the distal two-thirds of the RNA positive-sense genome are believed to be essential components of RNA replication complexes. To explore the functional relationships of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adcfc84229fa038cb100de302f49c12c
https://doi.org/10.1128/jvi.74.7.3253-3263.2000
https://doi.org/10.1128/jvi.74.7.3253-3263.2000
Autor:
James W. Crane, Petra L. Sedlak, Pankaj Sah, E. S. Louise Faber, John M. Power, Andrew J. Delaney
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(43)
Emotionally arousing events are particularly well remembered. This effect is known to result from the release of stress hormones and activation of β adrenoceptors in the amygdala. However, the underlying cellular mechanisms are not understood. Small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0926ecd49cdc615490e325d8298f1317
https://pubmed.ncbi.nlm.nih.gov/18945888
https://pubmed.ncbi.nlm.nih.gov/18945888
Autor:
Robert R, Rice, Andrew N, Muirhead, Bruce T, Harrison, Andrew J, Kassianos, Petra L, Sedlak, Narelle J, Maugeri, Peter J, Goss, Jonathan R, Davey, David E, James, Michael W, Graham
Publikováno v:
Methods in enzymology. 392
We describe two complementary strategies for preparing DNA-directed RNA interference (ddRNAi) constructs designed to express hpRNA. The first, oligonucleotide assembly (OA), uses a very simple annealing protocol to combine up to 20 short nucleotides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27499d4fbc78e5a5412b59f29b0ddef9
https://pubmed.ncbi.nlm.nih.gov/15644195
https://pubmed.ncbi.nlm.nih.gov/15644195
Autor:
Jonathan R. Davey, Peter J. Goss, David E. James, Narelle J. Maugeri, Michael W. Graham, Andrew N. Muirhead, Robert R. Rice, Petra L. Sedlak, Bruce Thomas Harrison, Andrew J. Kassianos
We describe two complementary strategies for preparing DNA-directed RNA interference (ddRNAi) constructs designed to express hpRNA. The first, oligonucleotide assembly (OA), uses a very simple annealing protocol to combine up to 20 short nucleotides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::799022caf6b0706e08dec47488dab8ba
https://doi.org/10.1016/s0076-6879(04)92024-1
https://doi.org/10.1016/s0076-6879(04)92024-1
We have previously reported successful trans -complementation of defective Kunjin virus genomic RNAs with a range of large lethal deletions in the nonstructural genes NS1, NS3, and NS5 (A. A. Khromykh et al., J. Virol. 74: 3253-3263, 2000). In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea94b15f671693f2f8837954760229fb
https://europepmc.org/articles/PMC136631/
https://europepmc.org/articles/PMC136631/
In order to study whether flavivirus RNA packaging is dependent on RNA replication, we generated two DNA-based Kunjin virus constructs, pKUN1 and pKUN1dGDD, allowing continuous production of replicating (wild-type) and nonreplicating (with a deletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf30cba62a8217611511be0b7714018
https://europepmc.org/articles/PMC114216/
https://europepmc.org/articles/PMC114216/