Výsledky vyhledávání - "Petra Jernvall"

Thyroid hormone receptor β1 in normal colon and colorectal cancer–association with differentiation, polypoid growth type and K-ras mutations

Autor: Tuomo T. Hörkkö, Karoliina Tuppurainen, Susannah M. C. George, Tuomo J. Karttunen, Markus J. Mäkinen, Petra Jernvall

Publikováno v: International Journal of Cancer. 118:1653-1659

The precursors for colorectal cancer include polypoid (conventional), flat and serrated adenomas. Polypoid growth in polypoid adenomas and serrated adenomas is associated with K-ras mutations. The regulation of polypoid or nonpolypoid growth is not w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70329b30d1bdfd9ba01628fca7538008
https://doi.org/10.1002/ijc.21556

Zobrazit plný text záznamu

Colorectal carcinoma associated with serrated adenoma - prevalence, histological features, and prognosis

Autor: Markus J. Mäkinen, Susannah M. C. George, Pirkko Vihko, Petra Jernvall, Tuomo J. Karttunen, Jyrki Mäkelä

Publikováno v: The Journal of Pathology. 193:286-294

Serrated adenoma has been proposed to be a distinct entity among colorectal neoplasms. Progression to frank carcinoma has been suggested in individual cases, but the prevalence of carcinomas originating from serrated adenomas and their clinico-pathol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8beb34aa2d5f507eb782634291ef8d2a
https://doi.org/10.1002/1096-9896(2000)9999:9999<::aid-path800>3.0.co

Zobrazit plný text záznamu

Classification of advanced colorectal carcinomas by tumor edge morphology

Autor: Markus J. Mäkinen, Tuomo J. Karttunen, Pirkko Vihko, Susannah M. C. George, Jyrki M. Mäkelä, Petra Jernvall

Publikováno v: Cancer. 89:1901-1909

BACKGROUND. Increasing evidence suggests that a substantial proportion of colorectal carcinomas develop without a preexisting polypoid adenomatous lesion, but it is difficult to detect the possible origin of advanced carcinomas. The purpose of this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cedd2728fac1efa4af3c275ed69369e0
https://doi.org/10.1002/1097-0142(20001101)89:9<1901::aid-cncr5>3.3.co

Zobrazit plný text záznamu

Classification of advanced colorectal carcinomas by tumor edge morphology

Autor: Jyrki Mäkelä, Pirkko Vihko, Tuomo J. Karttunen, Susannah M. C. George, Petra Jernvall, Markus J. Mäkinen

Publikováno v: Cancer. 89:1901-1909

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::390f4ffd13941cd5b2cd1fb8cffad3b0
https://doi.org/10.1002/1097-0142(20001101)89:9<1901::aid-cncr5>3.0.co

Zobrazit plný text záznamu

Conserved region mutations of thep53 gene are concentrated in distal colorectal cancers

Autor: Pirkko Vihko, Jyrki Mäkelä, Tuomo J. Karttunen, Petra Jernvall, Markus J. Mäkinen

Publikováno v: International Journal of Cancer. 74:97-101

Distal colorectal cancers, especially those in the rectum, are more aggressive and more commonly recurrent than proximal cancers. We studied the possible relationship between p53-gene mutation type and location of the tumour, since mutations in the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ac7259ea94d3a26a0c5590125acb557
https://doi.org/10.1002/(sici)1097-0215(19970220)74:1<97::aid-ijc17>3.0.co

Zobrazit plný text záznamu

17Beta-hydroxysteroid dehydrogenase type 2: independent prognostic significance and evidence of estrogen protection in female patients with colon cancer

Autor: Olayiwola Oduwole, Anitta E. Pulkka, Petra Jernvall, Pirkko Vihko, V. Isomaa, Markus J. Mäkinen, Tuomo J. Karttunen

Publikováno v: The Journal of steroid biochemistry and molecular biology. 87(2-3)

The mRNA expression of 17beta-hydroxysteroid dehydrogenase (17HSD) types 1 and 2 enzymes catalyzing opposite reaction of estrogen metabolism was investigated in colon cancer. Further, the significance of the 17HSD type 2 enzyme as a possible marker o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e674cfc9eeafade04896370e4baed6
https://pubmed.ncbi.nlm.nih.gov/14672733

Zobrazit plný text záznamu

Microsatellite instability: impact on cancer progression in proximal and distal colorectal cancers

Autor: Pirkko Vihko, Tuomo J. Karttunen, Markus J. Mäkinen, Jyrki Mäkelä, Petra Jernvall

Publikováno v: European journal of cancer (Oxford, England : 1990). 35(2)

Whilst individual planning of treatment and follow-up in every colorectal cancer case is an increasing demand, prognostic markers are needed for predicting cancer progression in the primary phase. We studied the effect of replication error (RER)-posi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99738f2c9e2cd6c092e8127b65e2e296
https://pubmed.ncbi.nlm.nih.gov/10448255

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání