Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Petra Janovska"'
Autor:
Barbora Judita Kasperova, Milos Mraz, Petr Svoboda, Daniel Hlavacek, Helena Kratochvilova, Istvan Modos, Nikola Vrzackova, Peter Ivak, Petra Janovska, Tatyana Kobets, Jakub Mahrik, Martin Riecan, Lenka Steiner Mrazova, Viktor Stranecky, Ivan Netuka, Tomas Cajka, Ondrej Kuda, Vojtech Melenovsky, Sona Stemberkova Hubackova, Martin Haluzik
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Sodium-glucose cotransporter 2 inhibitors (SGLT-2i) are glucose-lowering agents used for the treatment of type 2 diabetes mellitus, which also improve heart failure and decrease the risk of cardiovascular complications. Epicardial
Externí odkaz:
https://doaj.org/article/f5b7b9bcaae44ad086f3948fb34547db
Autor:
Olga Horakova, Gabriella Sistilli, Veronika Kalendova, Kristina Bardova, Marko Mitrovic, Tomas Cajka, Ilaria Irodenko, Petra Janovska, Karoline Lackner, Jan Kopecky, Martin Rossmeisl
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionNon-alcoholic fatty liver disease (NAFLD) can progress to more severe stages, such as steatohepatitis and fibrosis. Thermoneutral housing together with high-fat diet promoted NAFLD progression in C57BL/6J mice. Due to possible differences
Externí odkaz:
https://doaj.org/article/8f805a1becbe4000a52309d7f53c4d18
Autor:
Petra Janovska, Petr Zouhar, Kristina Bardova, Jakub Otahal, Marek Vrbacky, Tomas Mracek, Katerina Adamcova, Lucie Lenkova, Jiri Funda, Tomas Cajka, Zdenek Drahota, Sara Stanic, Arild C. Rustan, Olga Horakova, Josef Houstek, Martin Rossmeisl, Jan Kopecky
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101683- (2023)
Objective: Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and energy homeostasis. Other mech
Externí odkaz:
https://doaj.org/article/31f0b59f9117425794b61598c518ae9c
Autor:
Josef Oeckl, Petra Janovska, Katerina Adamcova, Kristina Bardova, Sarah Brunner, Sebastian Dieckmann, Josef Ecker, Tobias Fromme, Jiri Funda, Thomas Gantert, Piero Giansanti, Maria Soledad Hidrobo, Ondrej Kuda, Bernhard Kuster, Yongguo Li, Radek Pohl, Sabine Schmitt, Sabine Schweizer, Hans Zischka, Petr Zouhar, Jan Kopecky, Martin Klingenspor
Publikováno v:
Molecular Metabolism, Vol 61, Iss , Pp 101499- (2022)
Objective: Classical ATP-independent non-shivering thermogenesis enabled by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) is activated, but not essential for survival, in the cold. It has long been suspected that futile ATP-consuming subs
Externí odkaz:
https://doaj.org/article/02a486b5a3c54c2cbc43e4898dd4d342
Autor:
Jiří Funda, Josep A. Villena, Kristina Bardova, Katerina Adamcova, Illaria Irodenko, Pavel Flachs, Ivana Jedlickova, Eliska Haasova, Martin Rossmeisl, Jan Kopecky, Petra Janovska
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 4 (2022)
Impaired thermogenesis observed in mice with whole-body ablation of peroxisome proliferator-activated receptor-γ coactivator-1β (PGC-1β; officially known as PPARGC1B) may result from impaired brown fat (brown adipose tissue; BAT) function, but oth
Externí odkaz:
https://doaj.org/article/8c32943251774e9cad944271328acd81
Autor:
Petr Zouhar, Petra Janovska, Sara Stanic, Kristina Bardova, Jiri Funda, Blanka Haberlova, Birgitte Andersen, Martin Rossmeisl, Barbara Cannon, Jan Kopecky, Jan Nedergaard
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101324- (2021)
Objective: Administration of FGF21 to mice reduces body weight and increases body temperature. The increase in body temperature is generally interpreted as hyperthermia, i.e. a condition secondary to the increase in energy expenditure (heat productio
Externí odkaz:
https://doaj.org/article/a100dc94416a442f99f55a7a76712e79
Autor:
Katerina Adamcova, Olga Horakova, Kristina Bardova, Petra Janovska, Marie Brezinova, Ondrej Kuda, Martin Rossmeisl, Jan Kopecky
Publikováno v:
Marine Drugs, Vol 16, Iss 12, p 515 (2018)
We found previously that white adipose tissue (WAT) hyperplasia in obese mice was limited by dietary omega-3 polyunsaturated fatty acids (omega-3 PUFA). Here we aimed to characterize the underlying mechanism. C57BL/6N mice were fed a high-fat diet su
Externí odkaz:
https://doaj.org/article/8d95e460303942f7a0595c5428cd0a1f
Autor:
Olga Horakova, Dasa Medrikova, Evert M van Schothorst, Annelies Bunschoten, Pavel Flachs, Vladimir Kus, Ondrej Kuda, Kristina Bardova, Petra Janovska, Michal Hensler, Martin Rossmeisl, Rui Wang-Sattler, Cornelia Prehn, Jerzy Adamski, Thomas Illig, Jaap Keijer, Jan Kopecky
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43764 (2012)
Insulin resistance, the key defect in type 2 diabetes (T2D), is associated with a low capacity to adapt fuel oxidation to fuel availability, i.e., metabolic inflexibility. This, in turn, contributes to a further damage of insulin signaling. Effective
Externí odkaz:
https://doaj.org/article/6c369ad1fc064c589162e6d74ea2dcba
Autor:
Vladimir Kus, Pavel Flachs, Ondrej Kuda, Kristina Bardova, Petra Janovska, Michaela Svobodova, Zuzana Macek Jilkova, Martin Rossmeisl, Rui Wang-Sattler, Zhonghao Yu, Thomas Illig, Jan Kopecky
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27126 (2011)
Combining pharmacological treatments and life style interventions is necessary for effective therapy of major diseases associated with obesity, which are clustered in the metabolic syndrome. Acting via multiple mechanisms, combination treatments may
Externí odkaz:
https://doaj.org/article/ec7596b0b0bd4d8792261cf113de7428
Autor:
Jana Krizova, Martin Rossmeisl, Petra Janovska, Jan Kopecky, Jana Buresova, Jaap Keijer, Ondrej Kuda, Hana Hansikova, Inge van der Stelt
Publikováno v:
International Journal of Obesity 44 (2020)
International Journal of Obesity, 44, 235-244
International Journal of Obesity, 44, 235-244
Background/objective: Adaptation to the extrauterine environment depends on a switch from glycolysis to catabolism of fatty acids (FA) provided as milk lipids. We sought to learn whether the postnatal induction of muscle FA oxidation in mice could re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79d2f669da8c61e7a189d4747639530
https://doi.org/10.1038/s41366-018-0281-0
https://doi.org/10.1038/s41366-018-0281-0