Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Petra J. Ottens"'
Autor:
Fernanda Yamamoto Ricardo-da-Silva, Roberto Armstrong-Jr, Mayara Munhoz de Assis Ramos, Marina Vidal-dos-Santos, Cristiano Jesus Correia, Petra J. Ottens, Luiz Felipe Pinho Moreira, Henri G. D. Leuvenink, Ana Cristina Breithaupt-Faloppa
Publikováno v:
Biology of Sex Differences, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background Ex vivo lung perfusion (EVLP) is a useful tool for assessing lung grafts quality before transplantation. Studies indicate that donor sex is as an important factor for transplant outcome, as females present higher inflammatory resp
Externí odkaz:
https://doaj.org/article/63a6ac079b8340ee8222e94aca304d7c
Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys
Autor:
Neeltina M. Jager, Leonie H. Venema, Asel S. Arykbaeva, Anita H. Meter-Arkema, Petra J. Ottens, Cees van Kooten, Tom E. Mollnes, Ian P. J. Alwayn, Henri G. D. Leuvenink, Soeren E. Pischke, PROPER study consortium
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe gap between demand and supply of kidneys for transplantation necessitates the use of kidneys from extended criteria donors. Transplantation of these donor kidneys is associated with inferior results, reflected by an increased risk of de
Externí odkaz:
https://doaj.org/article/c1c57527154445c8add357819d54ed04
Autor:
Tobias M. Huijink, Leonie H. Venema, Rene A. Posma, Nynke J. deVries, Andrie C. Westerkamp, Petra J. Ottens, Daan J. Touw, Maarten W. Nijsten, Henri G.D. Leuvenink
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 222-230 (2021)
Metformin may act renoprotective prior to kidney transplantation by reducing ischemia‐reperfusion injury (IRI). This study examined whether metformin preconditioning and postconditioning during ex vivo normothermic machine perfusion (NMP) of rat an
Externí odkaz:
https://doaj.org/article/b2e77851cb714ad283b8a8487424d04a
Autor:
Judith E. van Zanden, MD,, Henri G.D. Leuvenink, PhD,, Erik A.M. Verschuuren, MD, PhD,, Zwanida J. Veldhuis, BSc,, Petra J. Ottens, BSc,, Michiel E. Erasmus, MD, PhD,, Maximilia C. Hottenrott, MD, PhD
Publikováno v:
Transplantation Direct, Vol 7, Iss 4, p e682 (2021)
Background. The onset of brain death (BD) leads to the deterioration of potential donor lungs. Methylprednisolone is considered to increase lung oxygenation capacity and enhance the procurement yield of donor lungs, when applied in situ, during donor
Externí odkaz:
https://doaj.org/article/9796230d9694491f91ed5c7594a3ceba
Autor:
Judith E. Van Zanden, Nils A. ’T Hart, Petra J. Ottens, Bo Liu, Rolando A. Rebolledo, Michiel E. Erasmus, Henri G. D. Leuvenink
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: The process of brain death (BD) leads to a pro-inflammatory state of the donor lung, which deteriorates its quality. In an attempt to preserve lung quality, methylprednisolone is widely recommended in donor lung management. However, clini
Externí odkaz:
https://doaj.org/article/1afef89b4ad54c299630b9dd7e5f6588
Autor:
Nynke J de Vries, Tobias M Huijink, Petra J. Ottens, Maarten W. N. Nijsten, Henri G. D. Leuvenink, Rene A. Posma, Andrie C. Westerkamp, Daan J Touw, Leonie H Venema
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 222-230 (2021)
Clinical and translational science, 14(1), 222-230. Wiley
Clinical and Translational Science
Clinical and translational science, 14(1), 222-230. Wiley
Clinical and Translational Science
Metformin may act renoprotective prior to kidney transplantation by reducing ischemia-reperfusion injury (IRI). This study examined whether metformin preconditioning and postconditioning duringex vivonormothermic machine perfusion (NMP) of rat and po
Autor:
Robert J. Porte, Ton Lisman, Masato Fujiyoshi, Andrie C. Westerkamp, Henri G. D. Leuvenink, Han Moshage, Petra J. Ottens, Tim A Berendsen, Vincent E de Meijer, Maarten W. N. Nijsten, Daan J Touw
Publikováno v:
Transplantation
Transplantation, 104(9), E271-E280. LIPPINCOTT WILLIAMS & WILKINS
Transplantation, 104(9), E271-E280. LIPPINCOTT WILLIAMS & WILKINS
Background. Preconditioning of donor livers before organ retrieval may improve organ quality after transplantation. We investigated whether preconditioning with metformin reduces preservation injury and improves hepatobiliary function in rat donor li
Autor:
Roberto Armstrong-Jr, Fernanda Yamamoto Ricardo-da-Silva, Marina Vidal-dos-Santos, Lucas Ferreira da Anunciação, Petra J. Ottens, Cristiano Jesus Correia, Luiz Felipe Pinho Moreira, Hendrik Gerrit Derk Leuvenink, Ana Cristina Breithaupt-Faloppa
Publikováno v:
Clinics, Volume: 78, Article number: 100222, Published: 10 JUL 2023
Background Clinical reports associate kidneys from female donors with worse prognostic in male recipients. Brain Death (BD) produces immunological and hemodynamic disorders that affect organ viability. Following BD, female rats are associated with in
Autor:
Rolando A Rebolledo, Anne C Van Erp, Petra J Ottens, Janneke Wiersema-Buist, Henri G D Leuvenink, Pamela Romanque
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0138749 (2015)
Thyroid hormone treatment in brain-dead organ donors has been extensively studied and applied in the clinical setting. However, its clinical applicability remains controversial due to a varying degree of success and a lack of mechanistic understandin
Externí odkaz:
https://doaj.org/article/68bb3f00c81c45e4bf132b3ed99ac0af
Autor:
Henri G. D. Leuvenink, Leonie H Venema, Andrie C. Westerkamp, Nynke J de Vries, Rene A. Posma, Tobias M Huijink, Petra J. Ottens, Frank Doesburg, Daan J Touw, Maarten W. N. Nijsten, J Roggeveld, A. Mireille A. Wessels
Publikováno v:
BMJ Open Diabetes Research & Care
BMJ Open Diabetes Research & Care, 8(1):e000816. BMJ PUBLISHING GROUP
BMJ Open Diabetes Research & Care, 8(1):e000816. BMJ PUBLISHING GROUP
IntroductionMetformin can accumulate and cause lactic acidosis in patients with renal insufficiency. Metformin is known to inhibit mitochondria, while renal secretion of the drug by proximal tubules indirectly requires energy. We investigated whether