Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Petra Hazon"'
Autor:
Agata Radwanska, Christopher Travis Cottage, Antonio Piras, Catherine Overed-Sayer, Carina Sihlbom, Ramachandramouli Budida, Catherine Wrench, Jane Connor, Susan Monkley, Petra Hazon, Holger Schluter, Matthew J. Thomas, Cory M. Hogaboam, Lynne A. Murray
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unmet medical need. It is characterized by formation of scar tissue leading to a progressive and irreversible decline in lung function. IPF is associated with repeated injury, which may alte
Externí odkaz:
https://doaj.org/article/893273a899624c7f8501668b4c65941b
Autor:
Victoria Ptasinski, Susan J Monkley, Karolina Öst, Markus Tammia, Hani N Alsafadi, Catherine Overed-Sayer, Petra Hazon, Darcy E Wagner, Lynne A Murray
Publikováno v:
Life Science Alliance. 6:e202201853
Repeated injury of the lung epithelium is proposed to be the main driver of idiopathic pulmonary fibrosis (IPF). However, available therapies do not specifically target the epithelium and human models of fibrotic epithelial damage with suitability fo
Autor:
Victoria Ptasinski, Susan J. Monkley, Karolina Öst, Markus Tammia, Catherine Overed-Sayer, Petra Hazon, Darcy E. Wagner, Lynne A. Murray
Repeated injury of the lung epithelium is proposed to be a main driver of idiopathic pulmonary fibrosis (IPF). However, none of the available therapies target the epithelium and there is a limited amount of human models of fibrotic epithelial damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f01dfdb4ac23bbdb138c14b2d754519e
https://doi.org/10.1101/2022.06.15.496102
https://doi.org/10.1101/2022.06.15.496102
Autor:
Xiaoyun Wang, Dave Singh, Joselyn Rojas-Quintero, Rory A. O'Donnell, Caroline A. Owen, Ratko Djukanovic, Duo Zhang, Robert Virtala, Petra Hazon, Andrew Higham, Jose Miguel Sanchez, Francesca Polverino, Ilyas Yambayev, Henric Olsson, Eva Lindqvist, Donna E. Davies, Susan J. Wilson, Danen Cunoosamy
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 198:1500-1518
Rationale: ADAMs (proteinases with a disintegrin and a metalloproteinase domain) have not been well studied in chronic obstructive pulmonary disease (COPD).Objectives: To investigate whether ADAM9 ...
Autor:
Xiaoyun, Wang, Francesca, Polverino, Joselyn, Rojas-Quintero, Duo, Zhang, José, Sánchez, Ilyas, Yambayev, Eva, Lindqvist, Robert, Virtala, Ratko, Djukanovic, Donna E, Davies, Susan, Wilson, Rory, O'Donnell, Danen, Cunoosamy, Petra, Hazon, Andrew, Higham, Dave, Singh, Henric, Olsson, Caroline A, Owen
Publikováno v:
American journal of respiratory and critical care medicine.
Proteinases with a disintegrin and a metalloproteinase domain (ADAMs) have not been well studied in COPD. We investigated whether ADAM9 is linked to COPD in humans and mice.ADAM9 blood and lung levels were measured in COPD patients versus controls, a
Autor:
Gustav Johansson, Petra Hazon, Matthew C. Catley, Pernilla Glader, Tiiu Saarne, Linda Swedin, Maria Rehnberg, Magdalena Niedzielska
Publikováno v:
Pharmacologytherapeutics. 169
Asthma is often described as an inflammatory disease of the lungs and in most patients symptomatic treatment with bronchodilators or inhaled corticosteroids is sufficient to control disease. Unfortunately there are a proportion of patients who fail t