Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Petra H. Nass"'
Autor:
Nabeel Akhter, John W. Harmon, Marco G. Cecchini, Petra H. Nass, Robert W. Malone, Antoinette Wetterwald, Colman K. Byrnes, Mark D. Duncan
Publikováno v:
Wound Repair and Regeneration. 12:397-403
Transfection of wounds with DNA-encoding growth factors has the potential to improve healing, but current means of nonviral gene delivery are inefficient. Repeated high doses of DNA, necessary to achieve reliable gene expression, are detrimental to h
Publikováno v:
Phytopathology®. 88:1031-1039
Barley yellow dwarf virus strain PAV (BYDV-PAV) RNA and the 17-kDa protein were localized in BYDV-PAV-infected oat cells using in situ hybridization and in situ immunolocalization assays, respectively. The in situ hybridization assay showed labeling
Autor:
Petra H. Nass, Richard A. Winchurch, Faisal G. Qureshi, Marcin T. Tchorzewski, Patricia J. Gearhart, John W. Harmon, Mark D. Duncan
Publikováno v:
Journal of Surgical Research. 77:99-103
Background.Topical application of growth factors to wounds has proven to be suboptimal in achieving epithelial growth and accelerating healing. We propose transfection of fibroblasts with a gene for acidic fibroblast growth factor (aFGF) which will a
Autor:
Nabeel Akhter, Narasimham L. Parinandi, John W. Harmon, Tarik Tihan, Viswanathan Natarajan, Colman K. Byrnes, Anil Bahadursingh, Mark D. Duncan, Petra H. Nass, Elizabeth A. Montgomery
Publikováno v:
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 7(2)
Esophageal reflux of duodenal contents converts a rat nitrosamine esophageal cancer model from squamous cell carcinoma to adenocarcinoma. Further, there was a tendency for male rats to have a higher incidence of cancer than female rats. However, chem
Publikováno v:
The Journal of surgical research. 108(1)
Background. Nonviral transfection of eukaryotic cells remains inefficient. Liposomes can transport DNA plasmid into the cytoplasm, but the nuclear membrane remains a barrier to efficient plasmid DNA transfection. But normal cells have mechanisms to t
Publikováno v:
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 6(1)
The major barrier to successful transfection appears to be passage of the DNA plasmid from the cytoplasm into the cell nucleus. The M9 nuclear localization peptide, a fragment of the naturally occurring heterogeneous nuclear ribonucleoprotein A1, whi
Autor:
Petra H Nass, Colman K. Byrnes, John W. Harmon, Chehada Hatoum, Mark D. Duncan, Faisal H. Khan
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 9(5)
Our group and others have previously reported enhancement of cutaneous wound healing following the transfection of tissue with plasmid vectors expressing the DNA for growth factors. In these experiments, growth factor treated animals were usually com
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 79(2-3)
Retinoids are proapoptotic compounds with therapeutic potential for treating cancer. We evaluated the apoptotic effect of the novel retinoid CD437, and particularly its relationship to Akt and acidic fibroblast growth factor (aFGF). We hypothesized t
Publikováno v:
Vaccine. 19(11-12)
To evaluate the utility of plasmid DNA vaccination against disease caused by herpes simplex virus (HSV), we compared the strength of protection against lethal challenge following natural virus infection with that following vaccination with a plasmid
Publikováno v:
The Journal of infectious diseases. 178(3)
Plasmid expression vectors were constructed that contained the genes encoding herpes simplex virus 1 (HSV-1) glycoproteins C (gC), D (gD), and E (gE). Mice receiving two intramuscular injections of expression plasmid (50 microg) produced a specific H