Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Petra G. Hirrlinger"'
Autor:
Johannes Hirrlinger, Grit Marx, Stefanie Besser, Marit Sicker, Susanne Köhler, Petra G. Hirrlinger, Sonja M. Wojcik, Volker Eulenburg, Ulrike Winkler, Swen Hülsmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Inhibitory neurons crucially contribute to shaping the breathing rhythm in the brain stem. These neurons use GABA or glycine as neurotransmitter; or co-release GABA and glycine. However, the developmental relationship between GABAergic, glycinergic a
Externí odkaz:
https://doaj.org/article/eacf9a0efb82488e95e9bb06cc3b99f4
Autor:
Dorit Schleinitz, Anna Seidel, Ruth Stassart, Jürgen Klammt, Petra G. Hirrlinger, Ulrike Winkler, Susanne Köhler, John T. Heiker, Ria Schönauer, Joanna Bialek, Knut Krohn, Katrin Hoffmann, Peter Kovacs, Johannes Hirrlinger
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Microcephaly is a devastating condition defined by a small head and small brain compared to the age- and sex-matched population. Mutations in a number of different genes causative for microcephaly have been identified, e.g., MCPH1, WDR62, and ASPM. R
Externí odkaz:
https://doaj.org/article/ca7ee63e04ea4bef90e3730765618b66
Autor:
Carolin Piotrowski, Vera Lede, Anne Butthof, Nicole Kaiser, Petra G Hirrlinger, Matthias H Tschöp, Torsten Schöneberg, Ingo Bechmann
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0187192 (2017)
Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfactory nerves. We have previously demonstrated that the cribriform plate is permissive for T cells and monocytes and that viruses can enter the bulb upon
Externí odkaz:
https://doaj.org/article/e1f7510872204f319045f72002dfea75
Autor:
Johannes Hirrlinger, Anja Scheller, Petra G Hirrlinger, Beate Kellert, Wannan Tang, Michael C Wehr, Sandra Goebbels, Andreas Reichenbach, Rolf Sprengel, Moritz J Rossner, Frank Kirchhoff
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4286 (2009)
Cre/LoxP recombination is the gold standard for conditional gene regulation in mice in vivo. However, promoters driving the expression of Cre recombinase are often active in a wide range of cell types and therefore unsuited to target more specific su
Externí odkaz:
https://doaj.org/article/45cf49cd2e404783b72af995f3e94da0
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Environmental enrichment for rodents is known to enhance motor performance. Structural and molecular changes have been reported to be coupled with an enriched environment, but functional alterations of single neurons remain elusive. Here, we compared
Autor:
Robert S. Ross, Ute Krügel, Stefanie Besser, Johannes Hirrlinger, Grit Bornschein, Petra G. Hirrlinger, Alice E. Zemljic-Harpf, Ulrike Winkler, Franziska Wilhelm, Marcello Sestu, Wolfgang H. Ziegler
Publikováno v:
Glia. 61:1067-1083
Astrocytes operate in close spatial relationship to other cells including neurons. Structural interaction is controlled by a dynamic interplay between actin-based cell motility and contact formation via cell-cell and cell-extracellular matrix adhesio
Autor:
Brian K. Kaspar, Daniel T. Lioy, Gail Mandel, Saurabh K. Garg, Frank Kirchhoff, Jacob Raber, Petra G. Hirrlinger, Kevin D. Foust, Nurit Ballas, Caitlin E. Monaghan, John M. Bissonnette
Publikováno v:
Nature. 475:497-500
Rett's syndrome (RTT) is an X-chromosome-linked autism spectrum disorder caused by loss of function of the transcription factor methyl-CpG-binding protein 2 (MeCP2). Although MeCP2 is expressed in most tissues, loss of MeCP2 expression results primar
Reactive glial cells: increased stiffness correlates with increased intermediate filament expression
Autor:
Elke Ulbricht, Thomas Pannicke, Petra G. Hirrlinger, Er-Qing Wei, Hartwig Wolburg, Nicole Körber, Milos Pekny, Ianors Iandiev, Ulrika Wilhelmsson, Yun-Bi Lu, Peter Wiedemann, Margrit Hollborn, Andreas Reichenbach, Andreas Bringmann, Josef A. Käs
Publikováno v:
The FASEB Journal. 25:624-631
Increased stiffness of reactive glial cells may impede neurite growth and contribute to the poor regenerative capabilities of the mammalian central nervous system. We induced reactive gliosis in rodent retina by ischemia-reperfusion and assessed inte
Autor:
Katja Rillich, Mirko Esche, Andreas Reichenbach, Yousef Yafai, Thomas Pannicke, Michael Weick, Petra G. Hirrlinger
Publikováno v:
Neuroscience Letters. 480:101-105
Signalling of sphingosine-1-phosphate (S1P) via G-protein-coupled receptors of the Endothelial Differentiation Gene family differentially regulates cellular processes such as migration, proliferation and morphogenesis in a variety of cell types. Prol
Autor:
Martin Zinkernagel, Christian Grimm, Sandrine Joly, Andreas Reichenbach, Elke Ulbricht, M. W. Seeliger, Marijana Samardzija, Bernhard Odermatt, Karl S. Lang, Johannes Hirrlinger, Petra G. Hirrlinger, Mike Francke, Charlotte E. Remé, Susanne C. Beck
Publikováno v:
The American Journal of Pathology. 174:2310-2323
Phagocytosis is essential for the removal of photoreceptor debris following retinal injury. We used two mouse models, mice injected with green fluorescent protein-labeled bone marrow cells or green fluorescent protein-labeled microglia, to study the