Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Petra Fischer"'
Autor:
Chien-Hung Yeh, Yifan Xu, Wenbin Shi, James J. Fitzgerald, Alexander L. Green, Petra Fischer, Huiling Tan, Ashwini Oswal
Publikováno v:
Brain Stimulation, Vol 17, Iss 3, Pp 501-509 (2024)
Background: Gait impairment has a major impact on quality of life in patients with Parkinson's disease (PD). It is believed that basal ganglia oscillatory activity at β frequencies (15–30 Hz) may contribute to gait impairment, but the precise dyna
Externí odkaz:
https://doaj.org/article/e955a831cd284eaca3c4937d849a3b18
Autor:
Damian M. Herz, Manuel Bange, Gabriel Gonzalez-Escamilla, Miriam Auer, Keyoumars Ashkan, Petra Fischer, Huiling Tan, Rafal Bogacz, Muthuraman Muthuraman, Sergiu Groppa, Peter Brown
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The neural mechanisms determining the speed of decisions and movements in the human brain remain poorly understood. Here, the authors reveal that the subthalamic nucleus causally controls decision and movement speed independently for each hemisphere.
Externí odkaz:
https://doaj.org/article/db37d446cea04765a2852e135410fe7c
Autor:
Petra Fischer, Alek Pogosyan, Alexander L. Green, Tipu Z. Aziz, Jonathan Hyam, Thomas Foltynie, Patricia Limousin, Ludvic Zrinzo, Michael Samuel, Keyoumars Ashkan, Mauro Da Lio, Mariolino De Cecco, Alberto Fornaser, Peter Brown, Huiling Tan
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 253-263 (2019)
Beta power suppression in the basal ganglia is stronger during movements that require high force levels and high movement effort but it has been difficult to dissociate the two. We recorded scalp EEG and basal ganglia local field potentials in Parkin
Externí odkaz:
https://doaj.org/article/c9ebe08c82b1497786a5985ace129c0d
Autor:
Theresa H. Wirtz, Philipp A. Reuken, Christian Jansen, Petra Fischer, Irina Bergmann, Christina Backhaus, Christoph Emontzpohl, Johanna Reißing, Elisa F. Brandt, M. Teresa Koenen, Kai M. Schneider, Robert Schierwagen, Maximilian J. Brol, Johannes Chang, Henning W. Zimmermann, Nilay Köse-Vogel, Thomas Eggermann, Ingo Kurth, Christian Stoppe, Richard Bucala, Jürgen Bernhagen, Michael Praktiknjo, Andreas Stallmach, Christian Trautwein, Jonel Trebicka, Tony Bruns, Marie-Luise Berres
Publikováno v:
JHEP Reports, Vol 3, Iss 2, Pp 100221- (2021)
Background & Aims: Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine and an important regulator of innate immune responses. We hypothesised that serum concentrations of MIF are associated with disease severity and outcome in pa
Externí odkaz:
https://doaj.org/article/74e1d74705f34501b1c9829b64a7c90a
Autor:
Verity M McClelland, Petra Fischer, Eleonora Foddai, Sofia Dall'Orso, Etienne Burdet, Peter Brown, Jean-Pierre Lin
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102569- (2021)
Dystonia is a disorder of sensorimotor integration associated with abnormal oscillatory activity within the basal ganglia-thalamo-cortical networks. Event-related changes in spectral EEG activity reflect cortical processing but are sparsely investiga
Externí odkaz:
https://doaj.org/article/7ebf482b770e409796e335469813fbf5
Autor:
Maria Teresa Koenen, Elisa Fabiana Brandt, Dawid Marcin Kaczor, Tim Caspers, Alexandra Catharina Anna Heinzmann, Petra Fischer, Daniel Heinrichs, Theresa Hildegard Wirtz, Christian Trautwein, Rory R Koenen, Marie-Luise Berres
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 698 (2022)
Hepatic steatosis and chronic hepatocyte damage ultimately lead to liver fibrosis. Key pathophysiological steps are the activation and transdifferentiation of hepatic stellate cells. We assessed the interplay between hepatocytes and hepatic stellate
Externí odkaz:
https://doaj.org/article/4e8430abd24040baae0357b784214c65
Autor:
Shenghong He, Abteen Mostofi, Emilie Syed, Flavie Torrecillos, Gerd Tinkhauser, Petra Fischer, Alek Pogosyan, Harutomo Hasegawa, Yuanqing Li, Keyoumars Ashkan, Erlick Pereira, Peter Brown, Huiling Tan
Publikováno v:
eLife, Vol 9 (2020)
Previous studies have explored neurofeedback training for Parkinsonian patients to suppress beta oscillations in the subthalamic nucleus (STN). However, its impacts on movements and Parkinsonian tremor are unclear. We developed a neurofeedback paradi
Externí odkaz:
https://doaj.org/article/03fe1beb28b24276bf5406c6b8022004
Autor:
Petra Fischer, Witold J Lipski, Wolf-Julian Neumann, Robert S Turner, Pascal Fries, Peter Brown, R Mark Richardson
Publikováno v:
eLife, Vol 9 (2020)
Cortico-basal ganglia interactions continuously shape the way we move. Ideas about how this circuit works are based largely on models those consider only firing rate as the mechanism of information transfer. A distinct feature of neural activity acco
Externí odkaz:
https://doaj.org/article/53f158ff278646829a20ecc875971403
Autor:
Gerd Tinkhauser, Flavie Torrecillos, Yann Duclos, Huiling Tan, Alek Pogosyan, Petra Fischer, Romain Carron, Marie-Laure Welter, Carine Karachi, Wim Vandenberghe, Bart Nuttin, Tatiana Witjas, Jean Régis, Jean-Philippe Azulay, Alexandre Eusebio, Peter Brown
Publikováno v:
Neurobiology of Disease, Vol 117, Iss , Pp 217-225 (2018)
Exaggerated activity in the beta band (13–35 Hz) is a hallmark of basal ganglia signals in patients with Parkinson's disease (PD). Beta activity however is not constantly elevated, but comes in bursts. In previous work we showed that the longer bet
Externí odkaz:
https://doaj.org/article/7f4738f40b104355ab4dfc07179ed0f2
Autor:
Chiung-Chu Chen, Chien-Hung Yeh, Hsiao-Lung Chan, Ya-Ju Chang, Po-Hsun Tu, Chih-Hua Yeh, Chin-Song Lu, Petra Fischer, Gerd Tinkhauser, Huiling Tan, Peter Brown
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
Freezing of gait (FOG) is a disabling clinical phenomenon often found in patients with advanced Parkinson's disease (PD). FOG impairs motor function, causes falls and leads to loss of independence. Whereas dual tasking that distracts patients' attent
Externí odkaz:
https://doaj.org/article/eef0df6af89c49f0b9c2dc76c7c11b2c