Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Petra E.T. Scholten"'
Autor:
Alfons J.M. van den Eertwegh, Natalie Sacks, Rik J. Scheper, Israel Lowy, Jean Marie Cuillerot, Petra E.T. Scholten, Helen Gall, Martine Reijm, Karin Jooss, Winald R. Gerritsen, Sinéad M. Lougheed, B. Mary E. von Blomberg, Anita G.M. Stam, Tanja D. de Gruijl, Saskia J. A. M. Santegoets, Kristen Hege
Publikováno v:
Cancer Immunology Immunotherapy, 62, 245-56
Cancer Immunology and Immunotherapy, 62(2), 245-256. Springer Science and Business Media Deutschland GmbH
Santegoets, S J A M, Stam, A G M, Lougheed, S M, Gall, H, Scholten, P E T, Reijm, M, Jooss, K, Sacks, N, Hege, K, Lowy, I, Cuillerot, J M, von Blomberg, B M E, Scheper, R J, van den Eertwegh, A J M, Gerritsen, W R & de Gruijl, T D 2013, ' T cell profiling reveals high CD4(+)CTLA-4(+) T cell frequency as dominant predictor for survival after Prostate GVAX/ipilimumab treatment ', Cancer Immunology and Immunotherapy, vol. 62, no. 2, pp. 245-256 . https://doi.org/10.1007/s00262-012-1330-5
Cancer Immunology Immunotherapy, 62, 2, pp. 245-56
Cancer Immunology and Immunotherapy, 62(2), 245-256. Springer Science and Business Media Deutschland GmbH
Santegoets, S J A M, Stam, A G M, Lougheed, S M, Gall, H, Scholten, P E T, Reijm, M, Jooss, K, Sacks, N, Hege, K, Lowy, I, Cuillerot, J M, von Blomberg, B M E, Scheper, R J, van den Eertwegh, A J M, Gerritsen, W R & de Gruijl, T D 2013, ' T cell profiling reveals high CD4(+)CTLA-4(+) T cell frequency as dominant predictor for survival after Prostate GVAX/ipilimumab treatment ', Cancer Immunology and Immunotherapy, vol. 62, no. 2, pp. 245-256 . https://doi.org/10.1007/s00262-012-1330-5
Cancer Immunology Immunotherapy, 62, 2, pp. 245-56
Item does not contain fulltext Immune checkpoint blockade enhances antitumor responses, but can also lead to severe immune-related adverse events (IRAE). To avoid unnecessary exposure to these potentially hazardous agents, it is important to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64421fe4dc84732c4795392fa926710
https://doi.org/10.1007/s00262-012-1330-5
https://doi.org/10.1007/s00262-012-1330-5
Autor:
Marco W.J. Schreurs, Wieke H.M. Verbeek, M Hadithi, Marije S. Goerres, Chris J. J. Mulder, Joost J. Oudejans, Petra E.T. Scholten, B. Mary E. von Blomberg, Abdulbaqi Al-toma
Publikováno v:
Clinical Immunology, 126(1), 48-56. Academic Press Inc.
Verbeek, W H M, Goerres, MS, von Blomberg, B M E, Oudejans, J J, Scholten, P E, al Hadithi, M, Al-toma, A, Schreurs, M W J & Mulder, C J J 2008, ' Flow cytometric determination of aberrant intra-epithelial lymphocytes predicts T-cell lymphoma development more accurately than T-cell clonality analysis in Refractory Celiac Disease ', Clinical Immunology, vol. 126, no. 1, pp. 48-56 . https://doi.org/10.1016/j.clim.2007.09.002
Verbeek, W H M, Goerres, MS, von Blomberg, B M E, Oudejans, J J, Scholten, P E, al Hadithi, M, Al-toma, A, Schreurs, M W J & Mulder, C J J 2008, ' Flow cytometric determination of aberrant intra-epithelial lymphocytes predicts T-cell lymphoma development more accurately than T-cell clonality analysis in Refractory Celiac Disease ', Clinical Immunology, vol. 126, no. 1, pp. 48-56 . https://doi.org/10.1016/j.clim.2007.09.002
Background: Refractory celiac disease (RCD) patients with aberrant, often clonal, intraepithelial T-cells are at high risk for development of enteropathy associated T-cell lymphoma (EATL). Early detection of those patients that actually develop EATL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a377a7272270e55cdaf670db00d0a4
https://doi.org/10.1016/j.clim.2007.09.002
https://doi.org/10.1016/j.clim.2007.09.002
Autor:
R. A. W. Van Lier, Chris H. Polman, B.W. van Oosten, Petra E.T. Scholten, Hans-Peter Hartung, M.H.G. Rep, K.W. Pflughaupt, H.J. Adèr, B.M.E. von Blomberg
Publikováno v:
Journal of neuroimmunology, 66(1-2), 49-55. Elsevier
Journal of Neuroimmunology, 66(1-2), 49-55. Elsevier
Van Oosten, B W, Rep, M H G, Van Lier, R A W, Scholten, P E T, Von Blomberg, B M E, Pflughaupt, K W, Hartung, H P, Adèr, H J & Polman, C H 1996, ' A pilot study investigating the effects of orally administered pentoxifylline on selected immune variables in patients with multiple sclerosis ', Journal of Neuroimmunology, vol. 66, no. 1-2, pp. 49-55 . https://doi.org/10.1016/0165-5728(96)00019-7
Journal of Neuroimmunology, 66(1-2), 49-55. Elsevier
Van Oosten, B W, Rep, M H G, Van Lier, R A W, Scholten, P E T, Von Blomberg, B M E, Pflughaupt, K W, Hartung, H P, Adèr, H J & Polman, C H 1996, ' A pilot study investigating the effects of orally administered pentoxifylline on selected immune variables in patients with multiple sclerosis ', Journal of Neuroimmunology, vol. 66, no. 1-2, pp. 49-55 . https://doi.org/10.1016/0165-5728(96)00019-7
Multiple sclerosis is probably mainly mediated by T-helper 1 (T(H)l)-lymphocytes. T(H)1-function can be down-regulated in vitro and in animal experiments by pentoxifylline. Therefore, we included 20 multiple sclerosis patients in an open label pilot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db82c53983f5780f76784a38569aa626
https://doi.org/10.1016/0165-5728(96)00019-7
https://doi.org/10.1016/0165-5728(96)00019-7
Autor:
Chris J. J. Mulder, Marco W.J. Schreurs, Wieke H.M. Verbeek, B. Mary E. von Blomberg, Petra E.T. Scholten, D Joop Kuik
Publikováno v:
American Journal of Gastroenterology, 103(12), 3152-3158. Springer Nature
Verbeek, W H M, von Blomberg, B M E, Scholten, P E, Kuik, D J, Mulder, C J J & Schreurs, M W 2008, ' The presence of small intestinal intraepithelial gamma/delta T-lymphocytes is inversely correlated with lymphoma development in refractory celiac disease ', American Journal of Gastroenterology, vol. 103, no. 12, pp. 3152-3158 . https://doi.org/10.1111/j.1572-0241.2008.02213.x
Verbeek, W H M, von Blomberg, B M E, Scholten, P E, Kuik, D J, Mulder, C J J & Schreurs, M W 2008, ' The presence of small intestinal intraepithelial gamma/delta T-lymphocytes is inversely correlated with lymphoma development in refractory celiac disease ', American Journal of Gastroenterology, vol. 103, no. 12, pp. 3152-3158 . https://doi.org/10.1111/j.1572-0241.2008.02213.x
In refractory celiac disease (RCD) type II, a phenotypically aberrant (CD7+ CD3- CD4/8-cytoplasmicCD3+) intraepithelial lymphocyte (IEL) population is present, and 50-60% of these patients develop enteropathy-associated T-cell lymphoma (EATL). TCRgam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a449f9956f8d6174c15a6ab1d0a423
https://research.vumc.nl/en/publications/df1920e5-7002-4aec-be3c-4120adc4a695
https://research.vumc.nl/en/publications/df1920e5-7002-4aec-be3c-4120adc4a695
Autor:
Otto Visser, Petra E.T. Scholten, Chris J. J. Mulder, Gert J. Ossenkoppele, Wieke H. M. Verbeek, Hyacintha M. van Roessel, B. Mary E. von Blomberg, Abdulbaqi Al-toma, Peter C. Huijgens
Publikováno v:
Blood. 109(5)
Autologous hematopoietic stem cell transplantation (ASCT) is an increasingly accepted treatment for refractory autoimmune diseases. Refractory celiac disease with aberrant T cells (RCD type II) is unresponsive to available therapies and carries a hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778d5c107f28ad2dace7f3a0943bfc71
https://pubmed.ncbi.nlm.nih.gov/17068146
https://pubmed.ncbi.nlm.nih.gov/17068146
Autor:
Petra E.T. Scholten, Herman J. Adèr, B. Mary E. von Blomberg, Chris H. Polman, Bob W. van Oosten, Frederik Barkhof
Publikováno v:
Archives of Neurology, 55(6), 793-798. American Medical Association
Van Oosten, B W, Barkhof, F, Scholten, P E T, Von Blomberg, B M E, Adèr, H J & Polman, C H 1998, ' Increased production of tumor necrosis factor α, and not of interferon γ, preceding disease activity in patients with multiple sclerosis ', Archives of Neurology, vol. 55, no. 6, pp. 793-798 . https://doi.org/10.1001/archneur.55.6.793
Van Oosten, B W, Barkhof, F, Scholten, P E T, Von Blomberg, B M E, Adèr, H J & Polman, C H 1998, ' Increased production of tumor necrosis factor α, and not of interferon γ, preceding disease activity in patients with multiple sclerosis ', Archives of Neurology, vol. 55, no. 6, pp. 793-798 . https://doi.org/10.1001/archneur.55.6.793
Objective: To study whether tumor necrosis factor (TNF) α or interferon (IFN) γ production by stimulated white blood cells precedes or accompanies clinical and magnetic resonance imaging signs of disease activity in patients with multiple sclerosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21becdfaa80bcde5bfe6282add845286
https://pubmed.ncbi.nlm.nih.gov/9626770
https://pubmed.ncbi.nlm.nih.gov/9626770
Autor:
Anita G.M. Stam, Winald R. Gerritsen, Tanja D. de Gruijl, Natalie Sacks, Sinéad M. Lougheed, Thomas Harding, Saskia J. A. M. Santegoets, Israel Lowy, Kristen Hege, Petra E.T. Scholten, Karin Jooss, Alfons J.M. van den Eertwegh, Helen Gall, Rik J. Scheper
Publikováno v:
Clinical Cancer Research. 16:B20-B20
The effects of a GM-CSF-secreting allogeneic prostate cancer vaccine (Prostate GVAX) and the anti-CTLA4 antibody Ipilimumab were investigated in a Phase I dose escalation/expansion trial of patients with metastatic, hormone-refractory prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccf63151ebc6b2d5b347c59d5d46f601
https://doi.org/10.1158/1078-0432.tcme10-b20
https://doi.org/10.1158/1078-0432.tcme10-b20
Autor:
N. Sacks, Thomas Harding, Helen Gall, Israel Lowy, Karin Jooss, Alfons J.M. van den Eertwegh, Petra E.T. Scholten, Winald R. Gerritsen, Saskia J. A. M. Santegoets, Rik J. Scheper, Kristen Hege, Tanja D. de Gruijl, Anita G.M. Stam, B. M. E. Von Blomberg
Publikováno v:
Cancer Research. 70:5588-5588
The effects of a GM-CSF-secreting allogeneic prostate cancer vaccine (Prostate GVAX) and the anti-CTLA4 antibody Ipilimumab were investigated in a Phase I dose escalation/expansion trial of patients with metastatic, hormone-refractory prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d37fb66c0e09260c805c009e7bc601e3
https://doi.org/10.1158/1538-7445.am10-5588
https://doi.org/10.1158/1538-7445.am10-5588
Autor:
Saskia J.A.M. Santegoets, Alfons J.M. van den Eertwegh, Sinead M. Lougheed, Anita G.M. Stam, Helen Gall, Petra E.T. Scholten, Mary B.E. von Blomberg, Erik Hooijberg, Karin Jooss, Nathalie Sacks, Minh Nguyen, Thomas Harding, Kristen Hege, Israel Lowy, Winald R. Gerritsen, Rik J. Scheper, Tanja D. de Gruijl
Publikováno v:
Cancer Research. 68:2538-2538
The effects of a combination of two allogeneic, GM-CSF-secreting prostate cancer cell lines (GVAX Immunotherapy for Prostate Cancer, Cell Genesys, Inc.) and escalating doses of the anti-CTLA4 antibody ipilimumab (MDX-010, Medarex, Inc.) are currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf6c9d145052e67a988d24cb5afeea33
https://doi.org/10.1158/1538-7445.am2008-2538
https://doi.org/10.1158/1538-7445.am2008-2538
Autor:
Petra E.T. Scholten, Chris J. J. Mulder, Wieke H. M. Verbeek, B. Mary E. von Blomberg, Marco W.J. Schreurs
Publikováno v:
Gastroenterology. 134:A-521
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2935add1717e3e4c4f73cec0b39ea47a
https://doi.org/10.1016/s0016-5085(08)62432-4
https://doi.org/10.1016/s0016-5085(08)62432-4