Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Petra Dames"'
Autor:
Dana Kuntzsch, Theresa Bergann, Petra Dames, Anja Fromm, Michael Fromm, Rohan A Davis, Matthias F Melzig, Joerg D Schulzke
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49426 (2012)
In a search for secondary plant compounds that bind to the glucocorticoid receptor (GR), the cyclobutane lignan endiandrin A was discovered from the rainforest tree Endiandra anthropophagorum Domin. Our present study aims to characterize the effect o
Externí odkaz:
https://doaj.org/article/6195fe6796c545c2af4270a22eee55dc
Autor:
Anja Fromm, Michael Fromm, In-Fah M. Lee, Jörg-Dieter Schulzke, Petra Dames, Turner, Jan F. Richter, Susanne M. Krug, Christian Bojarski
Publikováno v:
Mucosal immunology
In the two inflammatory bowel diseases, ulcerative colitis (UC) and Crohn’s disease (CD), altered expression of tight junction (TJ) proteins leads to an impaired epithelial barrier including increased uptake of luminal antigens supporting the infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e2f88b80da01360cd6423288866fc1
https://doi.org/10.1038/mi.2017.52
https://doi.org/10.1038/mi.2017.52
Autor:
Christian Barmeyer, Anja Fromm, Petra Dames, Michael Fromm, Jörg-Dieter Schulzke, Theresa Bergann, Roland Bücker, Susanne M. Krug
Publikováno v:
The Journal of Physiology. 593:5269-5282
Key points Interleukin-13 (IL-13) causes intestinal epithelial barrier dysfunction, and is implicated in the pathogenesis of Th2-driven intestinal inflammation (e.g. ulcerative colitis). However, it is unclear whether the epithelial sodium channel (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6029b4aa52d77fc754d80a3dedcbf403
https://doi.org/10.1113/jp271156
https://doi.org/10.1113/jp271156
Autor:
Burkhard Göke, Klaus G. Parhofer, Petra Dames, Andreas Lechner, Ramona Puff, M Weise, Jochen Seissler
Publikováno v:
Hormone and Metabolic Research. 43:306-311
Leptin receptor-deficient db/db mice are a commonly used research model and it is known that the genetic background, on which the mutation is bred, modulates the phenotype. While diabetes-resistant strains sustain near normal glycemia and hyperinsuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca12959db7f6c726358652358ecd807
https://doi.org/10.1055/s-0031-1271817
https://doi.org/10.1055/s-0031-1271817
Publikováno v:
Journal of Controlled Release. 143:243-250
Presence of CpG motifs within pDNA is widely reported to influence transgene expression as well as inflammatory response to nonviral gene vector complexes. Here, we analyzed gene expression kinetics and lung clearance after aerosol delivery of polyet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d39cec80aefefcc2f491b670e57e9dd
https://doi.org/10.1016/j.jconrel.2010.01.003
https://doi.org/10.1016/j.jconrel.2010.01.003
Autor:
Thomas Kirchner, Petra Dames, Andreas W. Flemmer, Eugenia Lesina, Carsten Rudolph, Kerstin Hajek, Iris Bittmann
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 74:427-434
Nonviral gene vectors have been shown to be therapeutically effective in various animal models of inherited and acquired lung diseases. Although an acute unmethylated CG dinucleotide (CpG)-mediated inflammatory response has been previously observed f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8473e1b19d3a069fc860da420e943d90
https://doi.org/10.1016/j.ejpb.2009.11.013
https://doi.org/10.1016/j.ejpb.2009.11.013
Autor:
Andreas Lechner, L van Bürck, Marlon R. Schneider, Nadja Herbach, Ruediger Wanke, Eckhard Wolf, Petra Dames, Maik Dahlhoff
Publikováno v:
Molecular and Cellular Endocrinology. 299:188-193
Betacellulin (BTC), a ligand of the epidermal growth factor receptor, has been shown to promote growth and differentiation of pancreatic beta-cells and to improve glucose metabolism in experimental diabetic rodent models. We employed transgenic mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729da267a6af1bdf6321dbff068a2bd1
https://doi.org/10.1016/j.mce.2008.11.022
https://doi.org/10.1016/j.mce.2008.11.022
Publikováno v:
The Journal of Gene Medicine. 9:820-829
Background It has been previously demonstrated that plasmid DNA transport into the nucleus could be increased by transcription factor binding. We chose the glucocorticoid responsive element (GRE) which binds to the glucocorticoid receptor (GR), a tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae61e727cff8ee4fc1a0752ce70e9da
https://doi.org/10.1002/jgm.1082
https://doi.org/10.1002/jgm.1082
Autor:
Christoph Loddenkemper, C. Bojarski, Irene Erko, Anja Fromm, Michael Fromm, Britta Siegmund, Petra Dames, Jörg-Dieter Schulzke, Michal R. Schweiger, Christian Barmeyer, Martin Kerick
Publikováno v:
Inflammatory bowel diseases. 22(3)
Background Lymphocytic colitis (LC) causes watery diarrhea. We aimed to identify mechanisms of altered Na absorption and regulatory inputs in patients with LC by examining the epithelial Na channel (ENaC) function as the predominant Na transport syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badf1a6992e2e9aa3838f7b1665f4705
https://pubmed.ncbi.nlm.nih.gov/26658215
https://pubmed.ncbi.nlm.nih.gov/26658215
Autor:
Petra, Dames, Theresa, Bergann, Anja, Fromm, Roland, Bücker, Christian, Barmeyer, Susanne M, Krug, Michael, Fromm, Jörg-Dieter, Schulzke
Publikováno v:
The Journal of physiology. 593(24)
Interleukin-13 (IL-13) causes intestinal epithelial barrier dysfunction, and is implicated in the pathogenesis of Th2-driven intestinal inflammation (e.g. ulcerative colitis). However, it is unclear whether the epithelial sodium channel (ENaC) - the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::428473051d0a647a6c53e92411f0fc74
https://pubmed.ncbi.nlm.nih.gov/28083943
https://pubmed.ncbi.nlm.nih.gov/28083943