Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Petra C. Schwalie"'
Autor:
Alberto Valdeolivas, Bettina Amberg, Nicolas Giroud, Marion Richardson, Eric J. C. Gálvez, Solveig Badillo, Alice Julien-Laferrière, Demeter Túrós, Lena Voith von Voithenberg, Isabelle Wells, Benedek Pesti, Amy A. Lo, Emilio Yángüez, Meghna Das Thakur, Michael Bscheider, Marc Sultan, Nadine Kumpesa, Björn Jacobsen, Tobias Bergauer, Julio Saez-Rodriguez, Sven Rottenberg, Petra C. Schwalie, Kerstin Hahn
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-16 (2024)
Abstract The consensus molecular subtypes (CMS) of colorectal cancer (CRC) is the most widely-used gene expression-based classification and has contributed to a better understanding of disease heterogeneity and prognosis. Nevertheless, CMS intratumor
Externí odkaz:
https://doaj.org/article/d6bdaa8d602c4df587d26a3ae4c61323
Autor:
Wanze Chen, Petra C. Schwalie, Eugenia V. Pankevich, Carine Gubelmann, Sunil K. Raghav, Riccardo Dainese, Marco Cassano, Michael Imbeault, Suk Min Jang, Julie Russeil, Tenagne Delessa, Julien Duc, Didier Trono, Christian Wolfrum, Bart Deplancke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Although Krüppel-associated box zinc finger proteins (KZFPs) were found to mostly repress transposable elements, recent studies found that KFZPs also play other roles in cells. Here, the authors provide evidence that the KZFP ZFP30 promotes adipogen
Externí odkaz:
https://doaj.org/article/79c0840feab948d880b74c9fb3a62bf1
Autor:
Yongguo Li, Petra C. Schwalie, Andrea Bast-Habersbrunner, Sabine Mocek, Julie Russeil, Tobias Fromme, Bart Deplancke, Martin Klingenspor
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 4099-4113.e5 (2019)
Summary: Recruitment of brite/beige cells, known as browning of white adipose tissue (WAT), is an efficient way to turn an energy-storing organ into an energy-dissipating one and may therefore be of therapeutic value in combating obesity. However, a
Externí odkaz:
https://doaj.org/article/e8c33942264047bf952373ee0b5ece87
Autor:
Tamás Schauer, Petra C. Schwalie, Ava Handley, Carla E. Margulies, Paul Flicek, Andreas G. Ladurner
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 271-282 (2013)
Chromatin organization and gene activity are responsive to developmental and environmental cues. Although many genes are transcribed throughout development and across cell types, much of gene regulation is highly cell-type specific. To readily track
Externí odkaz:
https://doaj.org/article/623e9b38cd34431eb0eea0a3706e3b28
Autor:
Alberto Valdeolivas, Bettina Amberg, Nicolas Giroud, Marion Richardson, Eric J.C. Gálvez, Solveig Badillo, Alice Julien-Laferrière, Demeter Turos, Lena Voith von Voithenberg, Isabelle Wells, Amy A. Lo, Emilio Yángüez, Meghna Das Thakur, Michael Bscheider, Marc Sultan, Nadine Kumpesa, Björn Jacobsen, Tobias Bergauer, Julio Saez-Rodriguez, Sven Rottenberg, Petra C. Schwalie, Kerstin Hahn
The heterogeneity of colorectal cancer (CRC) contributes to substantial differences in patient response to standard therapies. The consensus molecular subtypes (CMS) of CRC is the most widely-used gene expression-based classification and has contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da944b295388b36f4162857fc1d22e05
https://doi.org/10.1101/2023.01.23.525135
https://doi.org/10.1101/2023.01.23.525135
Autor:
Carles Fabregat-Franco, Changhoon Yoo, Bruno Sangro, Camilla Qvortrup, Hyung-Don Kim, Teresa Macarulla, Mariano Ponz-Sarvisé, Chia-Chi Lin, Do-Youn Oh, Thomas Yau, Juliana Bessa, Petra C. Schwalie, Steffen Dettling, Ramona Schlenker, Natascha Riede, Elia Hall, Felix Lichtenegger, Nicole Kratochwil, Thomas Pöschinger, Zhiwen Jiang, Tianyi Jiang, Christina Godfried Sie, Audrey Yeo Te-Ying, Christina Schiff, Sabine Hoves, Michael Cannarile
Publikováno v:
Cancer Research. 83:2342-2342
Background: It is hypothesized that TLR7 agonists reprogram myeloid cells in the TME, which may lead to activation of antitumor CD8 T effector cells and subsequently tumor cell death. The orally available TLR7 agonist prodrug RO7119929 is mainly conv
Autor:
Martin Ebeling, Luis Wyss, Alice Julien-Laferriere, Petra C. Schwalie, Albert S. W. Kang, Klas Hatje, Eric Ulrich, Laura Badi, Sophia Clara Mädler, Anthony Sonrel, Miroslav Phan, Jitao David Zhang, Roland Schmucki, Tony Kam-Thong
Publikováno v:
NAR Genomics and Bioinformatics, 3 (4)
NAR Genomics and Bioinformatics
NAR Genomics and Bioinformatics
Single-cell RNA sequencing (scRNA-seq) revolutionized our understanding of disease biology. The promise it presents to also transform translational research requires highly standardized and robust software workflows. Here, we present the toolkit Besc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bccdc856d62e1f52fceeecbeddc1957
https://hdl.handle.net/20.500.11850/529361
https://hdl.handle.net/20.500.11850/529361
Autor:
Bart Deplancke, Tobias Fromme, Peter Weber, Christoph Kiefer, Martin Klingenspor, Petra C. Schwalie, Yongguo Li, Anna Schießl, Andrea Bast-Habersbrunner
Publikováno v:
EMBO Reports
EMBO Rep.:e51289 (2021)
EMBO Rep.:e51289 (2021)
The recruitment of thermogenic brite adipocytes within white adipose tissue attenuates obesity and metabolic comorbidities, arousing interest in understanding the underlying regulatory mechanisms. The molecular network of brite adipogenesis, however,
Autor:
Laura, Codarri Deak, Valeria, Nicolini, Masao, Hashimoto, Maria, Karagianni, Petra C, Schwalie, Laura, Lauener, Eleni Maria, Varypataki, Marine, Richard, Esther, Bommer, Johannes, Sam, Stefanie, Joller, Mario, Perro, Floriana, Cremasco, Leo, Kunz, Emilio, Yanguez, Tamara, Hüsser, Ramona, Schlenker, Marisa, Mariani, Vinko, Tosevski, Sylvia, Herter, Marina, Bacac, Inja, Waldhauer, Sara, Colombetti, Xavier, Gueripel, Stephan, Wullschleger, Melanie, Tichet, Douglas, Hanahan, Haydn T, Kissick, Stephane, Leclair, Anne, Freimoser-Grundschober, Stefan, Seeber, Volker, Teichgräber, Rafi, Ahmed, Christian, Klein, Pablo, Umaña
Publikováno v:
Nature. 610(7930)
Expansion and differentiation of antigen-experienced PD-1
Autor:
Bettina Sobottka, Marta Nowak, Anja Laura Frei, Martina Haberecker, Samuel Merki, Mitchell P. Levesque, Reinhard Dummer, Holger Moch, Viktor Hendrik Koelzer, Rudolf Aebersold, Melike Ak, Faisal S. Al-Quaddoomi, Jonas Albinus, Ilaria Alborelli, Sonali Andani, Per-Olof Attinger, Marina Bacac, Daniel Baumhoer, Beatrice Beck-Schimmer, Niko Beerenwinkel, Christian Beisel, Lara Bernasconi, Anne Bertolini, Bernd Bodenmiller, Ximena Bonilla, Ruben Casanova, Stéphane Chevrier, Natalia Chicherova, Maya D'Costa, Esther Danenberg, Natalie Davidson, Monica-Andreea Drăganmoch, Stefanie Engler, Martin Erkens, Katja Eschbach, Cinzia Esposito, André Fedier, Pedro Ferreira, Joanna Ficek, Bruno Frey, Sandra Goetze, Linda Grob, Gabriele Gut, Detlef Günther, Pirmin Haeuptle, Viola Heinzelmann-Schwarz, Sylvia Herter, Rene Holtackers, Tamara Huesser, Anja Irmisch, Francis Jacob, Andrea Jacobs, Tim M. Jaeger, Katharina Jahn, Alva R. James, Philip M. Jermann, André Kahles, Abdullah Kahraman, Werner Kuebler, Jack Kuipers, Christian P. Kunze, Christian Kurzeder, Kjong-Van Lehmann, Sebastian Lugert, Gerd Maass, Markus G. Manz, Philipp Markolin, Julien Mena, Ulrike Menzel, Julian M. Metzler, Nicola Miglino, Emanuela S. Milani, Simone Muenst, Riccardo Murri, Charlotte K.Y. Ng, Stefan Nicolet, Patrick G.A. Pedrioli, Lucas Pelkmans, Salvatore Piscuoglio, Michael Prummer, Mathilde Ritter, Christian Rommel, María L. Rosano-González, Gunnar Rätsch, Natascha Santacroce, Jacobo Sarabia del Castillo, Ramona Schlenker, Petra C. Schwalie, Severin Schwan, Tobias Schär, Gabriela Senti, Franziska Singer, Sujana Sivapatham, Berend Snijder, Vipin T. Sreedharan, Stefan Stark, Daniel J. Stekhoven, Alexandre P.A. Theocharides, Tinu M. Thomas, Markus Tolnay, Vinko Tosevski, Nora C. Toussaint, Mustafa A. Tuncel, Marina Tusup, Audrey Van Drogen, Marcus Vetter, Tatjana Vlajnic, Sandra Weber, Walter P. Weber, Rebekka Wegmann, Michael Weller, Fabian Wendt, Norbert Wey, Andreas Wicki, Mattheus HE Wildschut, Bernd Wollscheid, Shuqing Yu, Johanna Ziegler, Marc Zimmermann, Martin Zoche, Gregor Zuend
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
CD8+ tumor-infiltrating T cells can be regarded as one of the most relevant predictive biomarkers in immune-oncology. Highly infiltrated tumors, referred to as inflamed (clinically “hot”), show the most favorable response to immune checkpoint inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d74ecfeeb15c1b4897606a94b52a648