Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Petra C Schwalie"'
Autor:
Cláudia S Ferreira, Konstanty Korski, Michael A Cannarile, Irina Klaman, Petra C Schwalie, Iakov I Davydov, Andreas Roller, Martha L Serrano-Serrano, Astrid Heller, Nicolas Staedler, Gabriele Dietmann, Alberto Valdeolivas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background The immune status of a patient’s tumor microenvironment (TME) may guide therapeutic interventions with cancer immunotherapy and help identify potential resistance mechanisms. Currently, patients’ immune status is mostly classified base
Externí odkaz:
https://doaj.org/article/a65b392cfd034dc18fbbd68b9a6b32bf
Autor:
Reinhard Dummer, Marina Bacac, Pablo Umana, Mitchell P Levesque, Christine Trumpfheller, Mi He, Bhavesh Soni, Petra C Schwalie, Tamara Hüsser, Caroline Waltzinger, Duvini De Silva, Ylva Prinz, Laura Krümpelmann, Samuele Calabro, Ines Matos, Maries van den Broek, Stephan Gasser
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/86af3a62742e4d618016ad79388f8eb6
Autor:
Carine Gubelmann, Petra C Schwalie, Sunil K Raghav, Eva Röder, Tenagne Delessa, Elke Kiehlmann, Sebastian M Waszak, Andrea Corsinotti, Gilles Udin, Wiebke Holcombe, Gottfried Rudofsky, Didier Trono, Christian Wolfrum, Bart Deplancke
Publikováno v:
eLife, Vol 3 (2014)
Adipose tissue is a key determinant of whole body metabolism and energy homeostasis. Unraveling the regulatory mechanisms underlying adipogenesis is therefore highly relevant from a biomedical perspective. Our current understanding of fat cell differ
Externí odkaz:
https://doaj.org/article/abc7a2880202452198b9d53ea60e7355
Autor:
Wanze Chen, Petra C. Schwalie, Eugenia V. Pankevich, Carine Gubelmann, Sunil K. Raghav, Riccardo Dainese, Marco Cassano, Michael Imbeault, Suk Min Jang, Julie Russeil, Tenagne Delessa, Julien Duc, Didier Trono, Christian Wolfrum, Bart Deplancke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Although Krüppel-associated box zinc finger proteins (KZFPs) were found to mostly repress transposable elements, recent studies found that KFZPs also play other roles in cells. Here, the authors provide evidence that the KZFP ZFP30 promotes adipogen
Externí odkaz:
https://doaj.org/article/79c0840feab948d880b74c9fb3a62bf1
Autor:
Alberto Valdeolivas, Bettina Amberg, Nicolas Giroud, Marion Richardson, Eric J.C. Gálvez, Solveig Badillo, Alice Julien-Laferrière, Demeter Turos, Lena Voith von Voithenberg, Isabelle Wells, Amy A. Lo, Emilio Yángüez, Meghna Das Thakur, Michael Bscheider, Marc Sultan, Nadine Kumpesa, Björn Jacobsen, Tobias Bergauer, Julio Saez-Rodriguez, Sven Rottenberg, Petra C. Schwalie, Kerstin Hahn
The heterogeneity of colorectal cancer (CRC) contributes to substantial differences in patient response to standard therapies. The consensus molecular subtypes (CMS) of CRC is the most widely-used gene expression-based classification and has contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da944b295388b36f4162857fc1d22e05
https://doi.org/10.1101/2023.01.23.525135
https://doi.org/10.1101/2023.01.23.525135
Autor:
Carles Fabregat-Franco, Changhoon Yoo, Bruno Sangro, Camilla Qvortrup, Hyung-Don Kim, Teresa Macarulla, Mariano Ponz-Sarvisé, Chia-Chi Lin, Do-Youn Oh, Thomas Yau, Juliana Bessa, Petra C. Schwalie, Steffen Dettling, Ramona Schlenker, Natascha Riede, Elia Hall, Felix Lichtenegger, Nicole Kratochwil, Thomas Pöschinger, Zhiwen Jiang, Tianyi Jiang, Christina Godfried Sie, Audrey Yeo Te-Ying, Christina Schiff, Sabine Hoves, Michael Cannarile
Publikováno v:
Cancer Research. 83:2342-2342
Background: It is hypothesized that TLR7 agonists reprogram myeloid cells in the TME, which may lead to activation of antitumor CD8 T effector cells and subsequently tumor cell death. The orally available TLR7 agonist prodrug RO7119929 is mainly conv
Autor:
Martin Ebeling, Luis Wyss, Alice Julien-Laferriere, Petra C. Schwalie, Albert S. W. Kang, Klas Hatje, Eric Ulrich, Laura Badi, Sophia Clara Mädler, Anthony Sonrel, Miroslav Phan, Jitao David Zhang, Roland Schmucki, Tony Kam-Thong
Publikováno v:
NAR Genomics and Bioinformatics, 3 (4)
NAR Genomics and Bioinformatics
NAR Genomics and Bioinformatics
Single-cell RNA sequencing (scRNA-seq) revolutionized our understanding of disease biology. The promise it presents to also transform translational research requires highly standardized and robust software workflows. Here, we present the toolkit Besc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bccdc856d62e1f52fceeecbeddc1957
https://hdl.handle.net/20.500.11850/529361
https://hdl.handle.net/20.500.11850/529361
Autor:
Bart Deplancke, Tobias Fromme, Peter Weber, Christoph Kiefer, Martin Klingenspor, Petra C. Schwalie, Yongguo Li, Anna Schießl, Andrea Bast-Habersbrunner
Publikováno v:
EMBO Reports
EMBO Rep.:e51289 (2021)
EMBO Rep.:e51289 (2021)
The recruitment of thermogenic brite adipocytes within white adipose tissue attenuates obesity and metabolic comorbidities, arousing interest in understanding the underlying regulatory mechanisms. The molecular network of brite adipogenesis, however,
Autor:
Laura, Codarri Deak, Valeria, Nicolini, Masao, Hashimoto, Maria, Karagianni, Petra C, Schwalie, Laura, Lauener, Eleni Maria, Varypataki, Marine, Richard, Esther, Bommer, Johannes, Sam, Stefanie, Joller, Mario, Perro, Floriana, Cremasco, Leo, Kunz, Emilio, Yanguez, Tamara, Hüsser, Ramona, Schlenker, Marisa, Mariani, Vinko, Tosevski, Sylvia, Herter, Marina, Bacac, Inja, Waldhauer, Sara, Colombetti, Xavier, Gueripel, Stephan, Wullschleger, Melanie, Tichet, Douglas, Hanahan, Haydn T, Kissick, Stephane, Leclair, Anne, Freimoser-Grundschober, Stefan, Seeber, Volker, Teichgräber, Rafi, Ahmed, Christian, Klein, Pablo, Umaña
Publikováno v:
Nature. 610(7930)
Expansion and differentiation of antigen-experienced PD-1
Autor:
Bettina Sobottka, Marta Nowak, Anja Laura Frei, Martina Haberecker, Samuel Merki, Mitchell P. Levesque, Reinhard Dummer, Holger Moch, Viktor Hendrik Koelzer, Rudolf Aebersold, Melike Ak, Faisal S. Al-Quaddoomi, Jonas Albinus, Ilaria Alborelli, Sonali Andani, Per-Olof Attinger, Marina Bacac, Daniel Baumhoer, Beatrice Beck-Schimmer, Niko Beerenwinkel, Christian Beisel, Lara Bernasconi, Anne Bertolini, Bernd Bodenmiller, Ximena Bonilla, Ruben Casanova, Stéphane Chevrier, Natalia Chicherova, Maya D'Costa, Esther Danenberg, Natalie Davidson, Monica-Andreea Drăganmoch, Stefanie Engler, Martin Erkens, Katja Eschbach, Cinzia Esposito, André Fedier, Pedro Ferreira, Joanna Ficek, Bruno Frey, Sandra Goetze, Linda Grob, Gabriele Gut, Detlef Günther, Pirmin Haeuptle, Viola Heinzelmann-Schwarz, Sylvia Herter, Rene Holtackers, Tamara Huesser, Anja Irmisch, Francis Jacob, Andrea Jacobs, Tim M. Jaeger, Katharina Jahn, Alva R. James, Philip M. Jermann, André Kahles, Abdullah Kahraman, Werner Kuebler, Jack Kuipers, Christian P. Kunze, Christian Kurzeder, Kjong-Van Lehmann, Sebastian Lugert, Gerd Maass, Markus G. Manz, Philipp Markolin, Julien Mena, Ulrike Menzel, Julian M. Metzler, Nicola Miglino, Emanuela S. Milani, Simone Muenst, Riccardo Murri, Charlotte K.Y. Ng, Stefan Nicolet, Patrick G.A. Pedrioli, Lucas Pelkmans, Salvatore Piscuoglio, Michael Prummer, Mathilde Ritter, Christian Rommel, María L. Rosano-González, Gunnar Rätsch, Natascha Santacroce, Jacobo Sarabia del Castillo, Ramona Schlenker, Petra C. Schwalie, Severin Schwan, Tobias Schär, Gabriela Senti, Franziska Singer, Sujana Sivapatham, Berend Snijder, Vipin T. Sreedharan, Stefan Stark, Daniel J. Stekhoven, Alexandre P.A. Theocharides, Tinu M. Thomas, Markus Tolnay, Vinko Tosevski, Nora C. Toussaint, Mustafa A. Tuncel, Marina Tusup, Audrey Van Drogen, Marcus Vetter, Tatjana Vlajnic, Sandra Weber, Walter P. Weber, Rebekka Wegmann, Michael Weller, Fabian Wendt, Norbert Wey, Andreas Wicki, Mattheus HE Wildschut, Bernd Wollscheid, Shuqing Yu, Johanna Ziegler, Marc Zimmermann, Martin Zoche, Gregor Zuend
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
CD8+ tumor-infiltrating T cells can be regarded as one of the most relevant predictive biomarkers in immune-oncology. Highly infiltrated tumors, referred to as inflamed (clinically “hot”), show the most favorable response to immune checkpoint inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d74ecfeeb15c1b4897606a94b52a648