Výsledky vyhledávání - "Petra C, Van Rijn"

Towards evidence-based pharmacotherapy in children

Autor: Desiree B. M. van der Werff, Peter C. Wierenga, Loraine Lie-A-Huen, E. M. Kemper, Maruschka P. Merkus, Petra C. Van Rijn, Martin Offringa

Publikováno v: Pediatric Anesthesia. 21:183-189

In daily practice, it is difficult to find a registered drug for children, because about 70% of the drugs prescribed in children are not studied, off-label or unlicensed in this age group. Clinical trials have usually been performed in adults, and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8dd2c83a81b559351442296dfe1eac60
https://doi.org/10.1111/j.1460-9592.2010.03493.x

Zobrazit plný text záznamu

Genetic Factors Are Relevant and Independent Determinants of Antihypertensive Drug Effects in a Multiracial Population

Autor: Henk-Jan Guchelaar, Petra C. van Rijn-Bikker, Richard P. Koopmans, Gert A. van Montfrans, Aeilko H. Zwinderman, Eric J.G. Sijbrands, Gideon Mairuhu

Publikováno v: American Journal of Hypertension, 22(12), 1295-1302. Oxford University Press
American journal of hypertension, 22(12), 1295-1302. Oxford University Press

BACKGROUND The success of anti hypertensive drugs may be improved by better prediction of their efficacy in individual patients. The objective of our study was to determine whether genetic variation predicts the individual systolic blood pressure (SB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77eb51ab0e257eb7ee37148a0ef3381d
https://doi.org/10.1038/ajh.2009.192

Zobrazit plný text záznamu

Quantitative determination of melatonin in human plasma and cerebrospinal fluid with high-performance liquid chromatography and fluorescence detection

Autor: Petra C. van Rijn-Bikker, Henk-Jan Guchelaar, Javier Sastre Torao, Paull Merkus

Publikováno v: Biomedical Chromatography, 14(5), 306-310. John Wiley and Sons Ltd
Torao, J S, Van Rijn-Bikker, P, Merkus, P & Guchelaar, H J 2000, ' Quantitative determination of melatonin in human plasma and cerebrospinal fluid with high-performance liquid chromatography and fluorescence detection ', Biomedical Chromatography, vol. 14, no. 5, pp. 306-310 . https://doi.org/10.1002/1099-0801(200008)14:5<306::AID-BMC986>3.0.CO;2-7

A validated new and precise reversed-phase high-performance liquid chromatographic method for the determination of melatonin in human plasma and cerebrospinal fluid, with 5-fluorotryptamine as internal standard, is described. Liquid-liquid extraction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79fa4e80ced374d6572e425d2ec49a30
https://doi.org/10.1002/1099-0801(200008)14:5<306::aid-bmc986>3.0.co

Zobrazit plný text záznamu

Pharmacokinetic-pharmacodynamic modeling of the antihypertensive effect of eprosartan in Black and White hypertensive patients

Autor: Oliver Ackaert, Ron A. A. Mathôt, Nelleke Snelder, Petra C. van Rijn-Bikker, Richard P. Koopmans, Reinier M. van Hest, Bart A. Ploeger

Publikováno v: Clinical pharmacokinetics, 52(9), 793-803. Adis International Ltd

It is well recognized that many antihypertensive drugs exhibit large interindividual variability in effect and that this wide range of patient response to antihypertensive drugs is a major problem in achieving blood pressure (BP) control. Variability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b83181ae405eaf34a5fb220cb2f6bf
https://pubmed.ncbi.nlm.nih.gov/23696281

Zobrazit plný text záznamu

Nonlinear mixed effects modeling of the diurnal blood pressure profile in a multiracial population

Autor: Reinier M. van Hest, Bart A. Ploeger, Oliver Ackaert, Petra C. van Rijn-Bikker, Gert A. van Montfrans, Richard P. Koopmans, Nelleke Snelder, Ron A. A. Mathôt

Publikováno v: American journal of hypertension, 26(9), 1103-1113. Oxford University Press

Background Cardiac and cerebrovascular events in hypertensive patients are related to specific features of the 24-hour diurnal blood pressure (BP) profile (i.e., daytime and nighttime BP, nocturnal dip (ND), and morning surge (MS)). This investigatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e9fd359f04789513d322b8c048dd81
https://pure.amc.nl/en/publications/nonlinear-mixed-effects-modeling-of-the-diurnal-blood-pressure-profile-in-a-multiracial-population(bb46b9d8-57d2-4599-83db-686cf46f5d9c).html